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13 API Suppliers, 4 USDMF, 2 EU WC, 1 KDMF, 3 NDC API, 10 Listed Suppliers

13 API Suppliers
4 USDMF
2 EU WC
1 KDMF
3 NDC API
10 Listed Suppliers

DEVELOPMENTS

2 Drugs in Development

2 Drugs in Development

INTERMEDIATES

3 Intermediates Suppliers

3 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

2 FDF Dossiers, 1 FDA Orange Book, 1 Listed Dossiers

2 FDF Dossiers
1 FDA Orange Book
1 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc, 13 SPI Pharma, 2 Seqens, 3 DKSH, 1 Jai Radhe Sales, 7 Gangwal Healthcare, 1 Pfanstiehl, 3 Actylis, 1 Aeon Procare, 5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 10 BASF, 9 Corel Pharma Chem, 3 DFE Pharma, 1 Finar, 7 Gangwal Chemicals, 3 Ideal Cures Pvt Ltd, 2 Ingredion Pharma Solutions, 9 Kerry, 1 Kima Chemical, 9 Microlex e.U, 2 Nomisma Healthcare, 1 Novo Excipients, 1 Pharmatrans-Sanaq, 3 Pluviaendo, 3 Prachin Chemical, 13 Roquette, 4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shijiazhuang Huaxu Pharmaceutical, 10 Sigachi Industries, 1 The Dow Chemical Company, 3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

41 Fillers, Diluents & Binders, 25 Coating Systems & Additives, 22 Direct Compression, 16 Controlled & Modified Release, 16 Thickeners and Stabilizers, 15 Disintegrants & Superdisintegrants, 13 Lubricants & Glidants, 13 Granulation, 13 Taste Masking, 11 Chewable & Orodispersible Aids, 11 Co-Processed Excipients, 8 Topical, 7 Parenteral, 6 Film Formers & Plasticizers, 4 Solubilizers, 3 Emulsifying Agents, 3 API Stability Enhancers, 2 Coloring Agents, 2 Rheology Modifiers

DIGITAL CONTENT

3 DATA COMPILATION #PharmaFlow, 40 NEWS #PharmaBuzz

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3 DATA COMPILATION #PharmaFlow
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3 Annual Reports

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3 Annual Reports

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7 APIs

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Synopsis

ACTIVE PHARMA INGREDIENTS

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2DRUGS IN DEVELOPMENT

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107

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133 RELATED EXCIPIENT COMPANIES

231EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Lorcaserin hcl, 846589-98-8, Lorqess, Lorcaserin (hydrochloride), Apd-356, Belviq

Molecular Formula

C₁₁H₁₅Cl₂N

Molecular Weight

232.15 g/mol

InChI Key

ITIHHRMYZPNGRC-QRPNPIFTSA-N

FDA UNII

0QJF08GDPE

1 2D Structure

Lorcaserin HCl

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(5R)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine;hydrochloride

2.1.2 InChI

InChI=1S/C11H14ClN.ClH/c1-8-7-13-5-4-9-2-3-10(12)6-11(8)9;/h2-3,6,8,13H,4-5,7H2,1H3;1H/t8-;/m0./s1

2.1.3 InChI Key

ITIHHRMYZPNGRC-QRPNPIFTSA-N

2.1.4 Canonical SMILES

CC1CNCCC2=C1C=C(C=C2)Cl.Cl

2.1.5 Isomeric SMILES

C[C@H]1CNCCC2=C1C=C(C=C2)Cl.Cl

2.2 Other Identifiers

2.2.1 UNII

0QJF08GDPE

2.3 Synonyms

2.3.1 MeSH Synonyms

1. (1r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine

2. 8-chloro-2,3,4,5-tetrahydro-1-methyl-1h-3-benzazepine

3. Apd 356

4. Apd-356

5. Apd356

6. Ar-10a

7. Belviq

8. Lorcaserin

2.3.2 Depositor-Supplied Synonyms

1. Lorcaserin Hcl

2. 846589-98-8

3. Lorqess

4. Lorcaserin (hydrochloride)

5. Apd-356

6. Belviq

7. (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-benzo[d]azepine Hydrochloride

8. Apd356

9. Lorcaserin Hydrochloride [usan]

10. Belviq Xr

11. 0qjf08gdpe

12. Chebi:65350

13. (1r)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1h-3-benzazepine Hydrochloride

14. 846589-98-8 (hcl)

15. Belviq (tn)

16. (r)-1h-3-benzazepine,8-chloro-2,3,4,5-tetrahydro-1-methyl-,hydrochloride

17. Lorcaserin Hydrochloride (usan)

18. (1r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine Hydrochloride

19. Unii-0qjf08gdpe

20. Apd 356

21. Schembl173899

22. Chembl2095211

23. Dtxsid60233650

24. Act10402

25. Bcp22731

26. Ex-a1697

27. Lorcaserin Hydrochloride (>50% Ee)

28. Lorcaserin Hydrochloride [mi]

29. Mfcd09833667

30. (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine Hydrochloride

31. Akos005145786

32. Ac-8945

33. Bcp9000859

34. Cs-0752

35. Ks-1439

36. 1h-3-benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-, Hydrochloride (1:1), (1r)-

37. Lorcaserin Hydrochloride [vandf]

38. Lorcaserin Hydrochloride [who-dd]

39. Lorcaserin Hydrochloride Anhydrous

40. Hy-15368

41. Sw219573-1

42. Lorcaserin Hydrochloride [orange Book]

43. D06613

44. Lorcaserin Hcl; Apd 356; Apd-356; Apd356;

45. Q27888442

46. (1r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepinium Chloride

47. (5r)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine;hydrochloride

48. (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine Hydrochloride Salt

49. (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-benzo[d]azepine Hydrochloride Hemihydrate

50. 1h-3-benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-, Hydrochloride, (1r)-

51. 1h-3-benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-,hydrochloride, (1r)-

2.4 Create Date

2006-10-26

3 Chemical and Physical Properties

Molecular Formula	C₁₁H₁₅Cl₂N
Molecular Weight	232.15 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	231.0581549 g/mol
Monoisotopic Mass	231.0581549 g/mol
Topological Polar Surface Area	12 Å²
Heavy Atom Count	14
Formal Charge	0
Complexity	172
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Belviq
PubMed Health	Lorcaserin (By mouth)
Drug Classes	Antiobesity Agent
Drug Label	BELVIQ (lorcaserin hydrochloride) is a serotonin 2C receptor agonist for oral administration used for chronic weight management. Its chemical name is (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate. The empirical f...
Active Ingredient	Lorcaserin hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	10mg
Market Status	Prescription
Company	Eisai

2 of 2
Drug Name	Belviq
PubMed Health	Lorcaserin (By mouth)
Drug Classes	Antiobesity Agent
Drug Label	BELVIQ (lorcaserin hydrochloride) is a serotonin 2C receptor agonist for oral administration used for chronic weight management. Its chemical name is (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate. The empirical f...
Active Ingredient	Lorcaserin hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	10mg
Market Status	Prescription
Company	Eisai

API SUPPLIERS

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USDMF

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Fillers, Diluents & Binders

Coating Systems & Additives

Direct Compression

Controlled & Modified Release

Thickeners and Stabilizers

Disintegrants & Superdisintegrants

Lubricants & Glidants

Granulation

Taste Masking

Chewable & Orodispersible Aids

Co-Processed Excipients

Topical

Parenteral

Film Formers & Plasticizers

Solubilizers

Emulsifying Agents

API Stability Enhancers

Coloring Agents

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Annual Reports

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APIs

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ABOUT THIS PAGE

List of Related Excipient Companies and Suppliers of Lorcaserin HCl on PharmaCompass.com

Lorcaserin HCl

ACCESS ALL DATA

Browse all information

CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

13 API Suppliers

4 USDMF

2 EU WC

1 KDMF

3 NDC API

10 Listed Suppliers

DEVELOPMENTS

2 Drugs in Development

INTERMEDIATES

3 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

2 FDF Dossiers

1 FDA Orange Book

1 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc

13 SPI Pharma

2 Seqens

3 DKSH

1 Jai Radhe Sales

7 Gangwal Healthcare

1 Pfanstiehl

3 Actylis

1 Aeon Procare

5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

10 BASF

9 Corel Pharma Chem

3 DFE Pharma

1 Finar

7 Gangwal Chemicals

3 Ideal Cures Pvt Ltd

2 Ingredion Pharma Solutions

9 Kerry

1 Kima Chemical

9 Microlex e.U

2 Nomisma Healthcare

1 Novo Excipients

1 Pharmatrans-Sanaq

3 Pluviaendo

3 Prachin Chemical

13 Roquette

4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

1 Shijiazhuang Huaxu Pharmaceutical

10 Sigachi Industries

1 The Dow Chemical Company

3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

41 Fillers, Diluents & Binders

25 Coating Systems & Additives

22 Direct Compression

16 Controlled & Modified Release

16 Thickeners and Stabilizers

15 Disintegrants & Superdisintegrants

13 Lubricants & Glidants

13 Granulation

13 Taste Masking

11 Chewable & Orodispersible Aids

11 Co-Processed Excipients

8 Topical

7 Parenteral

6 Film Formers & Plasticizers

4 Solubilizers

3 Emulsifying Agents

3 API Stability Enhancers

2 Coloring Agents

2 Rheology Modifiers

DIGITAL CONTENT

3 DATA COMPILATION #PharmaFlow

40 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

3 Annual Reports

MARKET PLACE

7 APIs