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    FAMAR CDMO- From early development to commercial manufacturing.

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    Chemistry

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    Also known as:
    Molecular Formula
    C9H13N5O4
    Molecular Weight
    255.23  g/mol
    InChI Key
    IRSCQMHQWWYFCW-UHFFFAOYSA-N
    Ganciclovir
    1 2D Structure

    Ganciclovir

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-3H-purin-6-one
    2.1.2 InChI
    InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
    2.1.3 InChI Key
    IRSCQMHQWWYFCW-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=NC2=C(N1COC(CO)CO)NC(=NC2=O)N
    2.1.5 Isomeric SMILES
    C1=NC2=C(N1COC(CO)CO)NC(=NC2=O)N
    2.2 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 255.23 g/mol
    Molecular Formula C9H13N5O4
    XLogP3-1.7
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count5
    Exact Mass255.09675391 g/mol
    Monoisotopic Mass255.09675391 g/mol
    Topological Polar Surface Area135 A^2
    Heavy Atom Count18
    Formal Charge0
    Complexity346
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 6  
    Drug NameCytovene
    PubMed HealthGanciclovir (Injection)
    Drug ClassesAntiviral
    Drug LabelGanciclovir is a synthetic guanine derivative active against cytomegalovirus (CMV). CYTOVENE-IV is the brand name for ganciclovir sodium for injection.CYTOVENE-IV is available as sterile lyophilized powder in strength of 500 mg per vial for intraveno...
    Active IngredientGanciclovir sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 500mg base/vial
    Market StatusPrescription
    CompanyRoche Palo

    2 of 6  
    Drug NameGanciclovir
    PubMed HealthGanciclovir
    Drug ClassesAntiviral
    Drug LabelGanciclovir is a synthetic guanine derivative active against cytomegalovirus (CMV).Ganciclovir is available as 250 mg and 500 mg capsules. Each capsule contains 250 mg or 500 mg ganciclovir, USP respectively, and inactive ingredients croscarmellose s...
    Active IngredientGanciclovir sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 500mg base/vial
    Market StatusPrescription
    CompanyFresenius Kabi Usa; Luitpold

    3 of 6  
    Drug NameZirgan
    PubMed HealthGanciclovir
    Drug ClassesAntiviral
    Drug LabelZIRGAN (ganciclovir ophthalmic gel) 0.15% contains a sterile, topical antiviral for ophthalmic use. The chemical name is 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (CAS number 82410-32-0). Ganciclovir is represented by the following structu...
    Active IngredientGanciclovir
    Dosage FormGel
    RouteOphthalmic
    Strength0.15%
    Market StatusPrescription
    CompanyBausch And Lomb

    4 of 6  
    Drug NameCytovene
    PubMed HealthGanciclovir (Injection)
    Drug ClassesAntiviral
    Drug LabelGanciclovir is a synthetic guanine derivative active against cytomegalovirus (CMV). CYTOVENE-IV is the brand name for ganciclovir sodium for injection.CYTOVENE-IV is available as sterile lyophilized powder in strength of 500 mg per vial for intraveno...
    Active IngredientGanciclovir sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 500mg base/vial
    Market StatusPrescription
    CompanyRoche Palo

    5 of 6  
    Drug NameGanciclovir
    PubMed HealthGanciclovir
    Drug ClassesAntiviral
    Drug LabelGanciclovir is a synthetic guanine derivative active against cytomegalovirus (CMV).Ganciclovir is available as 250 mg and 500 mg capsules. Each capsule contains 250 mg or 500 mg ganciclovir, USP respectively, and inactive ingredients croscarmellose s...
    Active IngredientGanciclovir sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 500mg base/vial
    Market StatusPrescription
    CompanyFresenius Kabi Usa; Luitpold

    6 of 6  
    Drug NameZirgan
    PubMed HealthGanciclovir
    Drug ClassesAntiviral
    Drug LabelZIRGAN (ganciclovir ophthalmic gel) 0.15% contains a sterile, topical antiviral for ophthalmic use. The chemical name is 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (CAS number 82410-32-0). Ganciclovir is represented by the following structu...
    Active IngredientGanciclovir
    Dosage FormGel
    RouteOphthalmic
    Strength0.15%
    Market StatusPrescription
    CompanyBausch And Lomb

    API Reference Price

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    20-Jan-2021
    17-Aug-2024
    KGS
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