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66 API Suppliers, 30 USDMF, 18 CEP/COS, 11 JDMF, 23 EU WC, 28 KDMF, 18 NDC API, 34 Listed Suppliers, $ API Reference Price

66 API Suppliers
30 USDMF
18 CEP/COS
11 JDMF
23 EU WC
28 KDMF
18 NDC API
34 Listed Suppliers
$ API Reference Price

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1 Drugs in Development

INTERMEDIATES

19 Intermediates Suppliers

19 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

508 FDF Dossiers, 80 FDA Orange Book, 221 Europe, 52 Canada, 44 Australia, 39 South Africa, 72 Listed Dossiers

508 FDF Dossiers
80 FDA Orange Book
221 Europe
52 Canada
44 Australia
39 South Africa
72 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

TABLET;ORAL - EQ 10MG BASE, TABLET;ORAL - EQ 20MG BASE, TABLET;ORAL - EQ 5MG BASE, SOLUTION;ORAL - EQ 5MG BASE/5ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

drugProductComposition
TABLET;ORAL - EQ 10MG BASE
TABLET;ORAL - EQ 20MG BASE
TABLET;ORAL - EQ 5MG BASE
SOLUTION;ORAL - EQ 5MG BASE/5ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

RELATED EXCIPIENT COMPANIES

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1 Minakem
3 Rochem International Inc
17 SPI Pharma
2 Seqens
4 DKSH
2 Jai Radhe Sales
1 Pharm-RX Chemical
2 Boai NKY Pharmaceuticals Ltd
13 Gangwal Healthcare
7 Nanjing Well Pharmaceutical
1 Pfanstiehl
1 ACG Worldwide
9 Actylis
1 Aeon Procare
8 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
21 BASF
2 Clariant
10 Corel Pharma Chem
5 DFE Pharma
2 Finar
10 Gangwal Chemicals
5 Ideal Cures Pvt Ltd
4 Ingredion Pharma Solutions
31 Kerry
4 Kima Chemical
6 Lonza Capsugel
16 Microlex e.U
1 Nanjing Bold Chemical
2 Nomisma Healthcare
2 Novo Excipients
2 Pharmatrans-Sanaq
7 Pluviaendo
3 Prachin Chemical
1 Qianhao Chemical (Hebei) Co., Ltd
1 Qualicaps
27 Roquette
13 Seppic
6 Shanghai Shenmei Pharmaceutical Technology Co., Ltd
2 Shijiazhuang Huaxu Pharmaceutical
11 Sigachi Industries
3 The Dow Chemical Company
1 Ulanqab Kema New Material
1 Valens Pharmachem
3 Vasa Pharmachem
1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

83 Fillers, Diluents & Binders, 50 Coating Systems & Additives, 39 Direct Compression, 30 Controlled & Modified Release, 29 Thickeners and Stabilizers, 28 Solubilizers, 24 Film Formers & Plasticizers, 22 Parenteral, 22 Disintegrants & Superdisintegrants, 22 Granulation, 18 Taste Masking, 18 Co-Processed Excipients, 17 Topical, 16 Chewable & Orodispersible Aids, 14 Lubricants & Glidants, 9 Rheology Modifiers, 8 Emulsifying Agents, 8 API Stability Enhancers, 5 Empty Capsules, 4 Coloring Agents, 4 Vegetarian Capsules, 4 Surfactant & Foaming Agents, 1 Soft Gelatin

DIGITAL CONTENT

2 DATA COMPILATION #PharmaFlow, 7 NEWS #PharmaBuzz

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2 DATA COMPILATION #PharmaFlow
7 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 128 Finished Drug Prices, 13 Annual Reports

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1 US Medicaid Prescriptions
128 Finished Drug Prices
13 Annual Reports

MARKET PLACE

10 APIs, 2 FDF Dossiers, 1 Intermediates

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10 APIs
2 FDF Dossiers
1 Intermediates

PATENTS & EXCLUSIVITIES

4 US Exclusivities

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4 US Exclusivities

REF. STANDARDS & IMPURITIES

1 EDQM , 1 USP , 3 Others

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1 EDQM
1 USP
3 Others

Virupaksha Escitalopram Oxalate

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 567

MARKET PLACE

API

FDF

19INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

508

FDF Dossiers

FDA Orange Book

221

Europe

Canada

Australia

South Africa

Listed Dossiers

1DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

165,062,650

Annual Reports (USD Million)

3,004

Finished Drug Prices

275 RELATED EXCIPIENT COMPANIES

475EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 219861-08-2, Lexapro, (s)-citalopram oxalate, Cipralex, Escitalopram (oxalate), (s)-(+)citalopram oxalate

Molecular Formula

C₂₂H₂₃FN₂O₅

Molecular Weight

414.4 g/mol

InChI Key

KTGRHKOEFSJQNS-BDQAORGHSA-N

FDA UNII

5U85DBW7LO

S-enantiomer of CITALOPRAM. Belongs to a class of drugs known as SELECTIVE SEROTONIN REUPTAKE INHIBITORS, used to treat depression and generalized anxiety disorder.

1 2D Structure

Escitalopram Oxalate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile;oxalic acid

2.1.2 InChI

InChI=1S/C20H21FN2O.C2H2O4/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;3-1(4)2(5)6/h4-9,12H,3,10-11,14H2,1-2H3;(H,3,4)(H,5,6)/t20-;/m0./s1

2.1.3 InChI Key

KTGRHKOEFSJQNS-BDQAORGHSA-N

2.1.4 Canonical SMILES

CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F.C(=O)(C(=O)O)O

2.1.5 Isomeric SMILES

CN(C)CCC[C@@]1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F.C(=O)(C(=O)O)O

2.2 Other Identifiers

2.2.1 UNII

5U85DBW7LO

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Escitalopram

2. Lexapro

2.3.2 Depositor-Supplied Synonyms

1. 219861-08-2

2. Lexapro

3. (s)-citalopram Oxalate

4. Cipralex

5. Escitalopram (oxalate)

6. (s)-(+)citalopram Oxalate

7. Lu 26-054-0

8. Escitalopram (as Oxalate)

9. Citalopram Oxalate, (s)-

10. Nsc-758934

11. 5u85dbw7lo

12. Lu-26-054-0

13. (s)-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile Oxalate

14. (1s)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3h-2-benzofuran-5-carbonitrile;oxalic Acid

15. Lu-26-054-o

16. Ncgc00095903-01

17. Dsstox_cid_26003

18. Dsstox_rid_81282

19. S-(+)-1-(3-(dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile Oxalate

20. Dsstox_gsid_46003

21. S-(+)-5-isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, Oxalate

22. Cas-219861-08-2

23. Escitalopram Oxalate [usan]

24. Gaudium

25. Entact

26. (s)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile Oxalate

27. Lexapro (tn)

28. Escitalopram Oxalate Inn

29. Unii-5u85dbw7lo

30. Schembl35123

31. Mls001401408

32. Spectrum1505216

33. (+)-(s)-citalopram Oxalate

34. Mld-55

35. (s)-citalopram Oxalate- Bio-x

36. Chembl1200322

37. Dtxsid1046003

38. Escitalopram Oxalate (jan/usp)

39. Escitalopram Oxalate [mi]

40. C20h21fn2o.c2h2o4

41. Escitalopram Oxalate [usan:usp]

42. Escitalopram Oxalate [jan]

43. Hms2051d11

44. Hms2231m16

45. Hms3370i17

46. Hms3393d11

47. Hms3713d16

48. Pharmakon1600-01505216

49. Bcp05686

50. Escitalopram Oxalate [vandf]

51. Tox21_111535

52. Ccg-39559

53. Escitalopram Oxalate [mart.]

54. Hy-14258a

55. Mfcd06407826

56. Nsc758934

57. Escitalopram Oxalate [usp-rs]

58. Escitalopram Oxalate [who-dd]

59. Akos016340275

60. Tox21_111535_1

61. Ac-6770

62. Cs-2054

63. Ks-1263

64. Nc00194

65. Nsc 758934

66. Sb17454

67. Ncgc00178555-02

68. 5-isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, (1s)-, Ethanedioate (1:1)

69. Bc164423

70. Escitalopram Oxalate [orange Book]

71. Smr000469191

72. Escitalopram Oxalate [ep Monograph]

73. Escitalopram Oxalate [usp Monograph]

74. E0958

75. D02567

76. Escitalopram Oxalate, >=98% (hplc), Powder

77. 861e082

78. A852070

79. Sr-01000763053

80. Sr-01000763053-3

81. Q27262882

82. Escitalopram Oxalate, Europepharmacopoeia (ep) Reference Standard

83. Escitalopram Oxalate, United States Pharmacopeia (usp) Reference Standard

84. Escitalopram For System Suitability, Europepharmacopoeia (ep) Reference Standard

85. Escitalopram Oxalate, Pharmaceutical Secondary Standard; Certified Reference Material

86. (+)-(s)-1-[3-(dimethylamino)propyl] -1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancar Bonitrile Oxalate

87. (+)-(s)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile Oxalate

88. 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran-carbonitrile Oxalate

89. 5-isobenzofurancarbonitrile,1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, (1s)-,ethanedioate (1:1)

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₂₃FN₂O₅
Molecular Weight	414.4 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	6
Exact Mass	414.15910000 g/mol
Monoisotopic Mass	414.15910000 g/mol
Topological Polar Surface Area	111 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	537
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Escitalopram oxalate
PubMed Health	Escitalopram (By mouth)
Drug Classes	Antianxiety, Antidepressant
Drug Label	Escitalopramoxalate USPis an orally administered selective serotonin reuptake inhibitor (SSRI). Escitalopram is the pure S-enantiomer (single isomer) of the racemic bicyclic phthalane derivative citalopram. Escitalopram oxalate is designated S-(+...
Active Ingredient	Escitalopram oxalate
Dosage Form	Tablet; Solution
Route	oral; Oral
Strength	5mg; eq 5mg base; eq 5mg base/5ml; 10mg; eq 20mg base; eq 10mg base; 20mg
Market Status	Tentative Approval; Prescription
Company	Watson Labs; Amneal Pharms; Mylan Pharma; Teva Pharms; Macleods Pharms; Caraco; Jubilant Generics; Sti Pharma; Apotex; Accord Hlthcare; Hetero Labs Ltd Iii; Aurobindo Pharma; Teva Pharms Usa; Taro; Torrent Pharms; Lupin; Zydus Pharms Usa; Dr Reddys Labs;

2 of 4
Drug Name	Lexapro
Drug Label	Lexapro (escitalopram oxalate) is an orally administered selective serotonin reuptake inhibitor (SSRI). Escitalopram is the pure S-enantiomer (single isomer) of the racemic bicyclic phthalane derivative citalopram. Escitalopram oxalate is designate...
Active Ingredient	Escitalopram oxalate
Dosage Form	Tablet; Solution
Route	oral; Oral
Strength	eq 5mg base; eq 5mg base/5ml; eq 20mg base; eq 10mg base
Market Status	Prescription
Company	Forest Labs

3 of 4
Drug Name	Escitalopram oxalate
PubMed Health	Escitalopram (By mouth)
Drug Classes	Antianxiety, Antidepressant
Drug Label	Escitalopramoxalate USPis an orally administered selective serotonin reuptake inhibitor (SSRI). Escitalopram is the pure S-enantiomer (single isomer) of the racemic bicyclic phthalane derivative citalopram. Escitalopram oxalate is designated S-(+...
Active Ingredient	Escitalopram oxalate
Dosage Form	Tablet; Solution
Route	oral; Oral
Strength	5mg; eq 5mg base; eq 5mg base/5ml; 10mg; eq 20mg base; eq 10mg base; 20mg
Market Status	Tentative Approval; Prescription
Company	Watson Labs; Amneal Pharms; Mylan Pharma; Teva Pharms; Macleods Pharms; Caraco; Jubilant Generics; Sti Pharma; Apotex; Accord Hlthcare; Hetero Labs Ltd Iii; Aurobindo Pharma; Teva Pharms Usa; Taro; Torrent Pharms; Lupin; Zydus Pharms Usa; Dr Reddys Labs;

4 of 4
Drug Name	Lexapro
Drug Label	Lexapro (escitalopram oxalate) is an orally administered selective serotonin reuptake inhibitor (SSRI). Escitalopram is the pure S-enantiomer (single isomer) of the racemic bicyclic phthalane derivative citalopram. Escitalopram oxalate is designate...
Active Ingredient	Escitalopram oxalate
Dosage Form	Tablet; Solution
Route	oral; Oral
Strength	eq 5mg base; eq 5mg base/5ml; eq 20mg base; eq 10mg base
Market Status	Prescription
Company	Forest Labs

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Selective Serotonin Reuptake Inhibitors

Compounds that specifically inhibit the reuptake of serotonin in the brain. (See all compounds classified as Selective Serotonin Reuptake Inhibitors.)

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Serotonin Uptake Inhibitors [MoA]; Serotonin Reuptake Inhibitor [EPC]

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API Reference Price

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LIMITED","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"425","totalValueFC":"131203","currency":"USD","unitRateINR":"36318.2","date":"12-Apr-2024","totalValueINR":"10895447.89","totalValueInUsd":"131203","indian_port":"Hyderabad Air","hs_no":"29329990","bill_no":"2992880","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"PADANG","supplierAddress":"XUNQIAO, LINHAI, ZHEJIANG, 317024 CHINASDNF China","customerAddress":"PLOT NO.2, MAITRIVIHAR,"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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DOSAGE - TABLET;ORAL - EQ 10MG BASE

USFDA APPLICATION NUMBER - 21323

DOSAGE - TABLET;ORAL - EQ 20MG BASE

USFDA APPLICATION NUMBER - 21323

DOSAGE - TABLET;ORAL - EQ 5MG BASE

USFDA APPLICATION NUMBER - 21323

DOSAGE - SOLUTION;ORAL - EQ 5MG BASE/5ML **Fe...DOSAGE - SOLUTION;ORAL - EQ 5MG BASE/5ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 21365

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ABOUT THIS PAGE

Escitalopram Manufacturers | Traders | Suppliers

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List of NDC API details of Escitalopram Active Pharmaceutical Ingredient listed on PharmaCompass.com

Escitalopram

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

66 API Suppliers

30 USDMF

18 CEP/COS

11 JDMF

23 EU WC

28 KDMF

18 NDC API

34 Listed Suppliers

$ API Reference Price

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1 Drugs in Development

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19 Intermediates Suppliers

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508 FDF Dossiers

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221 Europe

52 Canada

44 Australia

39 South Africa

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DRUG PRODUCT COMPOSITIONS

TABLET;ORAL - EQ 10MG BASE

TABLET;ORAL - EQ 20MG BASE

TABLET;ORAL - EQ 5MG BASE

SOLUTION;ORAL - EQ 5MG BASE/5ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

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EXCIPIENTS BY APPLICATIONS

SOLUTION;ORAL - EQ 5MG BASE/5ML Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons