menu
    • menu

    List of Suppliers' Lubricants Glidants Excipients Application used in DSSTox_CID_28982 on PharmaCompass.com

    Client Email Product
    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    Virtual Booth

    Contact Supplier

    FAMAR CDMO- From early development to commercial manufacturing.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-09-09

    Virtual Booth

    Contact Supplier

    Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients & provides custom-made solutions.

    Access Virtual Booth

    Contact Supplier

    Veranova: A CDMO that manages complexity with confidence.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-09-09

    Virtual Booth

    Contact Supplier

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    DIGITAL CONTENT

    GLOBAL SALES INFORMATION

    PATENTS & EXCLUSIVITIES

    PharmaCompass

    Synopsis

    Product SearchProduct Search

    Synopsis

    ACTIVE PHARMA INGREDIENTS

    6

    API Suppliers

    API Suppliers

    3

    USDMF

    US DMFs Filed

    0

    CEP/COS

    CEP/COS Certifications

    0

    JDMF

    JDMFs Filed

    3

    EU WC

    EU WC

    3

    KDMF

    KDMF

    4

    NDC API

    NDC API

    0

    VMF

    NDC API

    2

    Listed Suppliers

    Other Suppliers

    API REF. PRICE (USD/KG)

    $
    $ 0

    MARKET PLACE

    0

    API

    0

    FDF

    0INTERMEDIATES

    FINISHED DOSAGE FORMULATIONS

    10

    FDF Dossiers

    FDF Dossiers

    5

    FDA Orange Book

    FDA (Orange Book)

    1

    Europe

    Europe

    4

    Canada

    Canada

    0

    Australia

    Australia

    0

    South Africa

    South Africa

    0

    Listed Dossiers

    Listed Dossiers

    0 DRUGS IN DEVELOPMENT

    FDF Dossiers

    DRUG PRODUCT COMPOSITIONS

    REF. STANDARDS OR IMPURITIES

    0

    EDQM

    0

    USP

    0

    JP

    0

    Others

    PATENTS & EXCLUSIVITIES

    0

    US Patents

    0

    US Exclusivities

    3

    Health Canada Patents

    DIGITAL CONTENT

    0

    Data Compilation #PharmaFlow

    0

    Stock Recap #PipelineProspector

    0

    Weekly News Recap #Phispers

    5

    News #PharmaBuzz

    GLOBAL SALES INFORMATION

    US Medicaid

    4,300,795

    Annual Reports

    NA

    Finished Drug Prices

    NA

    171 RELATED EXCIPIENT COMPANIES

    268EXCIPIENTS BY APPLICATIONS

    Chemistry

    Click the arrow to open the dropdown
    read-moreClick the button for full data set
    read-moreClick the button for full data set
    Also known as: 158930-17-7, Frovatriptan succinate hydrate, Frovatriptan succinate monohydrate, Frovatriptan succinate [usan], Frovelan, Migard
    Molecular Formula
    C18H25N3O6
    Molecular Weight
    379.4  g/mol
    InChI Key
    CUETXFMONOSVJA-KLQYNRQASA-N
    FDA UNII
    D28J6W18HY
    Frovatriptan Succinate Hydrate
    Frovatriptan Succinate is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity. Frovatriptan succinate binds selectively and with high affinity to 5-HT 1B and presynaptic 5-HT 1D receptors in the extracerebral and intracranial arteries. This leads to an inhibition of serotonin activity and results in vasoconstriction of the painfully dilated blood vessels during migraine attack. Frovatriptan succinate is indicated for the acute treatment of migraine. (NCI05)
    1 2D Structure

    Frovatriptan Succinate Hydrate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    butanedioic acid;(6R)-6-(methylamino)-6,7,8,9-tetrahydro-5H-carbazole-3-carboxamide;hydrate
    2.1.2 InChI
    InChI=1S/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2/t9-;;/m1../s1
    2.1.3 InChI Key
    CUETXFMONOSVJA-KLQYNRQASA-N
    2.1.4 Canonical SMILES
    CNC1CCC2=C(C1)C3=C(N2)C=CC(=C3)C(=O)N.C(CC(=O)O)C(=O)O.O
    2.1.5 Isomeric SMILES
    CN[C@@H]1CCC2=C(C1)C3=C(N2)C=CC(=C3)C(=O)N.C(CC(=O)O)C(=O)O.O
    2.2 Other Identifiers
    2.2.1 UNII
    D28J6W18HY
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. (+)-(r)-5,6,7,8-tetrahydro-6-(methylamino)carbazole-3-carboxamide Succinate (1:1), Monohydrate

    2. 3-methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole

    3. Allegro

    4. Frova

    5. Frovatriptan

    6. Frovelan

    7. Sb 209509

    8. Vml-251

    9. Vml251

    2.3.2 Depositor-Supplied Synonyms

    1. 158930-17-7

    2. Frovatriptan Succinate Hydrate

    3. Frovatriptan Succinate Monohydrate

    4. Frovatriptan Succinate [usan]

    5. Frovelan

    6. Migard

    7. Vml 251

    8. Sb 209509-ax

    9. D28j6w18hy

    10. Sb 209509 Ax

    11. Nsc-760422

    12. Ncgc00183880-01

    13. Butanedioic Acid;(6r)-6-(methylamino)-6,7,8,9-tetrahydro-5h-carbazole-3-carboxamide;hydrate

    14. (+)-(r)-2,3,4,9-tetrahydro-3-(methylamino)-1h-carbazole-6-carboxamide Butanedioate (1:1), Monohydrate

    15. (+)-(r)-5,6,7,8-tetrahydro-6-(methylamino)carbazole-3-carboxamide Succinate (1:1), Monohydrate

    16. Butanedioic Acid, Compd. With (r)-2,3,4,9-tetrahydro-3-(methylamino)-1h-carbazole-6-carboxamide (1:1), Monohydrate

    17. Butanedioic Acid, Compd. With (r)-2,3,4,9-tetrahydro-3-(methylamino)-1h-carbazole-6-carboxamide, Hydrate (1:1:1)

    18. Frovatriptan Succinate (usan)

    19. Frovatriptan (succinate Hydrate)

    20. (r)-3-(methylamino)-2,3,4,9-tetrahydro-1h-carbazole-6-carboxamide Succinate Hydrate

    21. Butanedioic Acid,(6r)-6-methylamino-6,7,8,9-tetrahydro-5h-carbazole-3-carboxamide;hydrate

    22. Unii-d28j6w18hy

    23. Frova (tn)

    24. Dsstox_cid_28982

    25. Dsstox_rid_83247

    26. Dsstox_gsid_49056

    27. Schembl2321442

    28. Chembl2138684

    29. Dtxsid2049056

    30. Hy-b1658a

    31. Tox21_113606

    32. Akos030241886

    33. Frovatriptan Succinate [mart.]

    34. Frovatriptan Succinate [usp-rs]

    35. Nsc 760422

    36. 1h-carbazole-6-carboxamide, 2,3,4,9-tetrahydro-3-(methylamino)-, (r)-, Butanedioate (1:1), Monohydrate

    37. Frovatriptan Succinate [orange Book]

    38. Cas-158930-17-7

    39. Cs-0021309

    40. D04264

    41. Frovatriptan Succinate Monohydrate [mi]

    42. Frovatriptan Succinate Monohydrate [who-dd]

    43. Frovatriptan Succinate Monohydrate, >=97% (hplc)

    44. J-009548

    45. Q27276007

    46. Frovatriptan Succinate, United States Pharmacopeia (usp) Reference Standard

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 379.4 g/mol
    Molecular Formula C18H25N3O6
    Hydrogen Bond Donor Count6
    Hydrogen Bond Acceptor Count7
    Rotatable Bond Count5
    Exact Mass379.17433553 g/mol
    Monoisotopic Mass379.17433553 g/mol
    Topological Polar Surface Area147 Ų
    Heavy Atom Count27
    Formal Charge0
    Complexity426
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Serotonin Receptor Agonists

    Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS. (See all compounds classified as Serotonin Receptor Agonists.)

    Related Excipient Companies

    Upload your portfolio for free, ask us

    Excipients by Applications

    Click here to find the perfect excipient manufacturers by their capabilities

    Fillers, Diluents & Binders

    read-more
    read-more

    Coating Systems & Additives

    read-more
    read-more

    Controlled & Modified Release

    read-more
    read-more

    Direct Compression

    read-more
    read-more

    Thickeners and Stabilizers

    read-more
    read-more

    Granulation

    read-more
    read-more

    Disintegrants & Superdisintegrants

    read-more
    read-more

    Lubricants & Glidants

    read-more
    read-more

    Co-Processed Excipients

    read-more
    read-more

    Film Formers & Plasticizers

    read-more
    read-more

    Topical

    read-more
    read-more

    Empty Capsules

    read-more
    read-more

    Solubilizers

    read-more
    read-more

    API Stability Enhancers

    read-more
    read-more

    Taste Masking

    read-more
    read-more

    Coloring Agents

    read-more
    read-more

    Emulsifying Agents

    read-more
    read-more

    Vegetarian Capsules

    read-more
    read-more

    Chewable & Orodispersible Aids

    read-more
    read-more

    Parenteral

    read-more
    read-more

    Rheology Modifiers

    read-more
    read-more

    Digital Content read-more

    Create Content with PharmaCompass, ask us

    NEWS #PharmaBuzz

    read-more
    read-more

    Global Sales Information

    Do you need Business Intel? Ask us

    Patents & EXCLUSIVITIES

    Check the patents & exclusivity for this product

    ABOUT THIS PAGE

    Ask Us for Pharmaceutical Supplier and Partner
    Ask Us, Find A Supplier / Partner
    No Commissions, No Strings Attached, Get Connected for FREE

    What are you looking for?

    How can we help you?

    The request can't be empty

    Please read our Privacy Policy carefully

    You must agree to the privacy policy

    The name can't be empty
    The company can't be empty.
    The email can't be empty Please enter a valid email.
    The mobile can't be empty

    Market Place

    Market Place

    PharmaCompass

    Home

    Market Place

    Menu

    Post Enquiry

    Post Enquiry

    Market Place

    Market Place

    Search