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ACTIVE PHARMA INGREDIENTS

9 API Suppliers, 5 USDMF, 2 KDMF, 3 NDC API, 6 Listed Suppliers, $ API Reference Price

9 API Suppliers
5 USDMF
2 KDMF
3 NDC API
6 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

19 FDF Dossiers, 16 FDA Orange Book, 1 South Africa, 2 Listed Dossiers

19 FDF Dossiers
16 FDA Orange Book
1 South Africa
2 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

TABLET;ORAL - 25MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, TABLET, EXTENDED RELEASE;ORAL - 75MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

drugProductComposition
TABLET;ORAL - 25MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
TABLET, EXTENDED RELEASE;ORAL - 75MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc, 17 SPI Pharma, 8 Boai NKY Pharmaceuticals Ltd, 11 Gangwal Healthcare, 1 Nanjing Well Pharmaceutical, 1 Pfanstiehl, 1 Actylis, 1 Aeon Procare, 1 Alcedo Pharmachem, 5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 14 BASF, 5 Corel Pharma Chem, 4 DFE Pharma, 6 Gangwal Chemicals, 1 Ideal Cures Pvt Ltd, 3 Ingredion Pharma Solutions, 21 Kerry, 1 Lonza Capsugel, 5 Lubrizol Life Science Health, 13 Microlex e.U, 2 Novo Excipients, 3 Pharmatrans-Sanaq, 5 Pluviaendo, 2 Prachin Chemical, 15 Roquette, 1 Seppic, 5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shanghai Welltone Material Technology Co., Ltd, 1 Shijiazhuang Huaxu Pharmaceutical, 10 Sigachi Industries, 2 The Dow Chemical Company, 3 Ulanqab Kema New Material, 2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

78 Fillers, Diluents & Binders, 42 Direct Compression, 22 Disintegrants & Superdisintegrants, 22 Granulation, 21 Thickeners and Stabilizers, 19 Co-Processed Excipients, 17 Controlled & Modified Release, 16 Chewable & Orodispersible Aids, 15 Solubilizers, 14 Lubricants & Glidants, 13 Taste Masking, 7 Parenteral, 7 Coating Systems & Additives, 6 Topical, 3 Film Formers & Plasticizers, 2 API Stability Enhancers, 2 Rheology Modifiers, 1 Vegetarian Capsules, 1 Emulsifying Agents

DIGITAL CONTENT

2 NEWS #PharmaBuzz

media
2 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

3 Finished Drug Prices

globalSalesInformation
3 Finished Drug Prices

MARKET PLACE

3 APIs, 1 FDF Dossiers

marketPlace
3 APIs
1 FDF Dossiers

REF. STANDARDS & IMPURITIES

1 USP , 1 Others

otherSolutions
1 USP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 64

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

172 RELATED EXCIPIENT COMPANIES

308EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Amfepramone hydrochloride, 134-80-5, Moderatan, Dobesin, Tenuate, Diethylpropion hcl

Molecular Formula

C₁₃H₂₀ClNO

Molecular Weight

241.76 g/mol

InChI Key

ICFXZZFWRWNZMA-UHFFFAOYSA-N

FDA UNII

19V2PL39NG

A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)

1 2D Structure

Diethylpropion Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-(diethylamino)-1-phenylpropan-1-one;hydrochloride

2.1.2 InChI

InChI=1S/C13H19NO.ClH/c1-4-14(5-2)11(3)13(15)12-9-7-6-8-10-12;/h6-11H,4-5H2,1-3H3;1H

2.1.3 InChI Key

ICFXZZFWRWNZMA-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CCN(CC)C(C)C(=O)C1=CC=CC=C1.Cl

2.2 Other Identifiers

2.2.1 UNII

19V2PL39NG

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2-diethylaminopropiophenone

2. Amfepramon

3. Amfepramone

4. Anorex

5. Delgamer

6. Diethylpropion

7. Dietil Retard

8. Dietil-retard

9. Dietilretard

10. Hydrochloride, Diethylpropion

11. Ifa Norex

12. Lipomin

13. Maruate

14. Modratan

15. Neobes

16. Nobesine

17. Norex, Ifa

18. Phepranon

19. Prfamone

20. Propion

21. Regenon

22. Regibon

23. Tenuate

24. Tepanil

2.3.2 Depositor-Supplied Synonyms

1. Amfepramone Hydrochloride

2. 134-80-5

3. Moderatan

4. Dobesin

5. Tenuate

6. Diethylpropion Hcl

7. Tepanil

8. Anorex

9. Tenuate Dospan

10. Regenon Hydrochloride

11. 2-(diethylamino)propiophenone Hydrochloride

12. Amfepramone (hydrochloride)

13. Prefamone

14. Regenon

15. Amphepramonum Hydrochloride

16. 1-propanone, 2-(diethylamino)-1-phenyl-, Hydrochloride

17. 19v2pl39ng

18. Diethylpropion Hydrochloride Civ

19. Alpha-benzoyltriethylammonium Chloride

20. Alpha-benzoyltriethylamine Hydrochloride

21. D03801

22. Diethylpropion Hydrochloride [usp]

23. Menutil

24. 1-phenyl-2-diethylaminopropanone-1 Hydrochloride

25. Magrex Retard

26. Tenuate-dospan

27. Amfepramon Hydrochloride

28. Lineal-rivo

29. Tepanil Ten-tab

30. Nu-dispoz

31. Dsstox_cid_27816

32. Dsstox_rid_82580

33. Dsstox_gsid_47838

34. Propiophenone, 2-(diethylamino)-, Hydrochloride

35. Diethylpropion Hydrochloride (usp)

36. 2-(diethylamino)-1-phenylpropan-1-one Hydrochloride

37. Cas-134-80-5

38. Chebi:643703

39. 2-diethylaminopropiophenone Hydrochloride

40. Sr-01000220674

41. Ncgc00167475-01

42. Einecs 205-156-5

43. Unii-19v2pl39ng

44. Tenuate (tn)

45. Rac Diethylpropion-d10 Hydrochloride

46. Diethylproion Hydrochloride

47. Cambridge Id 5809497

48. Chembl1693

49. Schembl15483

50. 2-(diethylamino)-1-phenyl-1-propanone Hydrochloride

51. 2-(diethylamino)-1-phenylpropan-1-one;hydrochloride

52. Dtxsid4047838

53. Hy-b0981

54. Tox21_112479

55. Akos015962206

56. Tox21_112479_1

57. Ccg-220122

58. Cs-4472

59. Diethylpropion Hydrochloride [mi]

60. Ncgc00167475-02

61. Ac-16025

62. Amfepramone Hydrochloride [who-dd]

63. As-16865

64. Diethylpropion Hydrochloride [mart.]

65. Diethylpropion Hydrochloride [vandf]

66. Diethylpropion Hydrochloride [usp-rs]

67. .alpha.-benzoyltriethylamine Hydrochloride

68. 090d846

69. Diethylpropion Hydrochloride [orange Book]

70. Diethylpropion Hydrochloride [usp Monograph]

71. Sr-01000220674-1

72. Sr-01000220674-2

73. Q27105182

74. Diethylpropion Hydrochloride Solution, 1.0 Mg/ml In Methanol (with 1% 1 M Hcl; As Free Base), Certified Reference Material

2.4 Create Date

2005-07-29

3 Chemical and Physical Properties

Molecular Formula	C₁₃H₂₀ClNO
Molecular Weight	241.76 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	5
Exact Mass	241.1233420 g/mol
Monoisotopic Mass	241.1233420 g/mol
Topological Polar Surface Area	20.3 Å²
Heavy Atom Count	16
Formal Charge	0
Complexity	193
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 6
Drug Name	Diethylpropion hydrochloride
Active Ingredient	Diethylpropion hydrochloride
Dosage Form	Tablet, extended release; Tablet
Route	Oral
Strength	75mg; 25mg
Market Status	Prescription
Company	Lannett Holdings; Corepharma; Avanthi

2 of 6
Drug Name	Tenuate
Active Ingredient	Diethylpropion hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	25mg
Market Status	Prescription
Company	Watson Pharms

3 of 6
Drug Name	Tenuate dospan
PubMed Health	Diethylpropion (By mouth)
Drug Classes	Appetite Suppressant, Centrally Acting
Drug Label	Diethylpropion hydrochloride, USPis available for oral administration in immediate-release tablets containing 25 mg diethylpropion hydrochloride. The inactive ingredients in each immediate-release tablet are: corn starch, lactose monohydrate, magne...
Active Ingredient	Diethylpropion hydrochloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	75mg
Market Status	Prescription
Company	Watson Pharms

4 of 6
Drug Name	Diethylpropion hydrochloride
Active Ingredient	Diethylpropion hydrochloride
Dosage Form	Tablet, extended release; Tablet
Route	Oral
Strength	75mg; 25mg
Market Status	Prescription
Company	Lannett Holdings; Corepharma; Avanthi

5 of 6
Drug Name	Tenuate
Active Ingredient	Diethylpropion hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	25mg
Market Status	Prescription
Company	Watson Pharms

6 of 6
Drug Name	Tenuate dospan
PubMed Health	Diethylpropion (By mouth)
Drug Classes	Appetite Suppressant, Centrally Acting
Drug Label	Diethylpropion hydrochloride, USPis available for oral administration in immediate-release tablets containing 25 mg diethylpropion hydrochloride. The inactive ingredients in each immediate-release tablet are: corn starch, lactose monohydrate, magne...
Active Ingredient	Diethylpropion hydrochloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	75mg
Market Status	Prescription
Company	Watson Pharms

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Appetite Depressants

Agents that are used to suppress appetite. (See all compounds classified as Appetite Depressants.)

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Increased Sympathetic Activity [PE]; Sympathomimetic Amine Anorectic [EPC]; Appetite Suppression [PE]

API SUPPLIERS

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USDMF

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KDMF

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NDC API

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Listed Suppliers

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API Reference Price

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POINT"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724697000,"product":"BIS-MPA (104119) (DIMETHYLOLPROPIONIC ACID)","address":"105, BAJAJ BHAVAN, NARIMAN POINT","city":"MUMBAI","supplier":"PERSTORP S.P.A.","supplierCountry":"ITALY","foreign_port":"GENOA","customer":"C J S ","customerCountry":"INDIA","quantity":"10000.00","actualQuantity":"10000","unit":"KGS","unitRateFc":"6","totalValueFC":"61305.8","currency":"USD","unitRateINR":"509.1","date":"27-Aug-2024","totalValueINR":"5091000","totalValueInUsd":"61305.8","indian_port":"JNPT","hs_no":"29181990","bill_no":"5278962","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"GENOA","supplierAddress":"SOCIO UNICO-CORSO SEMPIONE 13 I-21053 CASTELLANZA (VA) ITALYSDNF Italy","customerAddress":"105, BAJAJ BHAVAN, NARIMAN POINT"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724697000,"product":"PHARMA INSREDIENTS BETAMETHASONE DIPROPIONATIE EP (REJECTEDGOODS)","address":"708, TIMES SQUARE ARCADE,","city":"AHMEDABAD","supplier":"JSC AKRIKHIN","supplierCountry":"INDIA","foreign_port":"MOSCOW DOMODEDOVO","customer":"SKJ HEALTHCARE PRIVATE LIMITED","customerCountry":"INDIA","quantity":"24.95","actualQuantity":"24.945","unit":"KGS","unitRateFc":"112000","totalValueFC":"34021.9","currency":"INR","unitRateINR":"113260","date":"27-Aug-2024","totalValueINR":"2825270.7","totalValueInUsd":"34021.9","indian_port":"Ahmedabad Air","hs_no":"29372900","bill_no":"5274278","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"MOSCOW DOMODEDOVO","supplierAddress":"KIROVA STREET 29, STARAYAKUPAVNA,BOGORODSKYMOSCOW REGION 142450, RUSSIA RU","customerAddress":"708, TIMES SQUARE ARCADE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724956200,"product":"ETHYL PROPIONATE","address":"PLOT NO.26,2ND CROSS,JIGANI","city":"BANGALORE","supplier":"GIVAUDAN SINGAPORE PTE ","supplierCountry":"MEXICO","foreign_port":"SINGAPORE","customer":"GIVAUDAN INDIA PRIVATE ","customerCountry":"INDIA","quantity":"360.00","actualQuantity":"360","unit":"KGS","unitRateFc":"6.5","totalValueFC":"2402.7","currency":"USD","unitRateINR":"554.3","date":"30-Aug-2024","totalValueINR":"199530.01","totalValueInUsd":"2402.7","indian_port":"JNPT","hs_no":"29155000","bill_no":"5327318","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"MEXICO","selfForZScoreResived":"Pharma Grade","supplierPort":"SINGAPORE","supplierAddress":"1 WOODLANDS AVE 8SINGAPORE 738972SDNF SINGAPORE","customerAddress":"PLOT NO.26,2ND CROSS,JIGANI"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724956200,"product":"METHYL 3-METHYLTHIOPROPIONATE (AROMATIC CHEMICAL)","address":"1-5 SEVEN WELLS STREET","city":"CHENNAI ,TAMILNADU","supplier":"NATARA GLOBAL LTD","supplierCountry":"UNITED KINGDOM","foreign_port":"LEEDS","customer":"INTERNATIONAL FLAVORS AND FRAGRANCES","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"97.3","totalValueFC":"618","currency":"USD","unitRateINR":"10264.2","date":"30-Aug-2024","totalValueINR":"51321.03","totalValueInUsd":"618","indian_port":"Madras Air","hs_no":"29309096","bill_no":"5334332","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED KINGDOM","selfForZScoreResived":"Pharma Grade","supplierPort":"LEEDS","supplierAddress":"ZINC WORKS ROAD NORTH GARE SEATON CAREW HARTLEPOOL TS25 2DTSDNF GB","customerAddress":"1-5 SEVEN WELLS STREET"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725042600,"product":"3- (2-CHLOROPHENYL) PROPIONIC ACID : COO : CN","address":"UDAISAGAR ROAD,","city":"UDAIPUR RAJASTHAN","supplier":"YANCUI IMPORT & ","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"PI INDUSTRIES LIMITED","customerCountry":"INDIA","quantity":"15000.00","actualQuantity":"15","unit":"MTS","unitRateFc":"18000","totalValueFC":"275876.2","currency":"USD","unitRateINR":"1527300","date":"31-Aug-2024","totalValueINR":"22909500","totalValueInUsd":"275876.2","indian_port":"JNPT","hs_no":"29163990","bill_no":"5346089","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"FLAT\/RM 1611B 16\/F HO KING COMMERCIAL CENTRE 2-16 FA YUEN STREET MONGKOK,KL.HONG KONG Hong Kong","customerAddress":"UDAISAGAR ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725042600,"product":"R-(+)-2-(4-HYDROXY PHENOXY) PROPIONIC ACID (DHPPA)","address":"FMC FORTUNA, 4TH FLOOR,","city":"KOLKATA, W.B.","supplier":"NORCHEM JIANGSU CORPORATION","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"KRISHI RASAYAN EXPORTS PVT.LTD.","customerCountry":"INDIA","quantity":"12800.00","actualQuantity":"12800","unit":"KGS","unitRateFc":"9.9","totalValueFC":"129046.3","currency":"USD","unitRateINR":"837.2","date":"31-Aug-2024","totalValueINR":"10716351.36","totalValueInUsd":"129046.3","indian_port":"Hazira","hs_no":"29189990","bill_no":"5353787","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ROOM NO. 703, WANDA PLAZA B, NO. 106 MIDDLE JIANGDONG ROAD, Nanjing -210017, CHINA","customerAddress":"FMC FORTUNA, 4TH FLOOR,"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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FDF Dossiers

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - TABLET;ORAL - 25MG **Federal Registe...DOSAGE - TABLET;ORAL - 25MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 11722

DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 75MG...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 75MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 12546

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Excipients by Applications

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Fillers, Diluents & Binders

Direct Compression

Disintegrants & Superdisintegrants

Granulation

Thickeners and Stabilizers

Co-Processed Excipients

Controlled & Modified Release

Chewable & Orodispersible Aids

Solubilizers

Lubricants & Glidants

Taste Masking

Parenteral

Coating Systems & Additives

Topical

Film Formers & Plasticizers

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Rheology Modifiers

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ABOUT THIS PAGE

List of Suppliers' Solubilizers Excipients Application used in DIETHYLPROPION HCL. on PharmaCompass.com

DIETHYLPROPION HCL.

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

9 API Suppliers

5 USDMF

2 KDMF

3 NDC API

6 Listed Suppliers

$ API Reference Price

FINISHED DOSAGE FORMULATIONS

19 FDF Dossiers

16 FDA Orange Book

1 South Africa

2 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

TABLET;ORAL - 25MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

TABLET, EXTENDED RELEASE;ORAL - 75MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc

17 SPI Pharma

8 Boai NKY Pharmaceuticals Ltd

11 Gangwal Healthcare

1 Nanjing Well Pharmaceutical

1 Pfanstiehl

1 Actylis

1 Aeon Procare

1 Alcedo Pharmachem

5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

14 BASF

5 Corel Pharma Chem

4 DFE Pharma

6 Gangwal Chemicals

1 Ideal Cures Pvt Ltd

3 Ingredion Pharma Solutions

21 Kerry

1 Lonza Capsugel

5 Lubrizol Life Science Health

13 Microlex e.U

2 Novo Excipients

3 Pharmatrans-Sanaq

5 Pluviaendo

2 Prachin Chemical

15 Roquette

1 Seppic

5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

1 Shanghai Welltone Material Technology Co., Ltd

1 Shijiazhuang Huaxu Pharmaceutical

10 Sigachi Industries

2 The Dow Chemical Company

3 Ulanqab Kema New Material

2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

78 Fillers, Diluents & Binders

42 Direct Compression

22 Disintegrants & Superdisintegrants

22 Granulation

21 Thickeners and Stabilizers

19 Co-Processed Excipients

17 Controlled & Modified Release

16 Chewable & Orodispersible Aids

15 Solubilizers

14 Lubricants & Glidants

13 Taste Masking

7 Parenteral

7 Coating Systems & Additives

6 Topical

3 Film Formers & Plasticizers

2 API Stability Enhancers

2 Rheology Modifiers

1 Vegetarian Capsules

1 Emulsifying Agents

DIGITAL CONTENT

2 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

3 Finished Drug Prices

MARKET PLACE

TABLET;ORAL - 25MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons

TABLET, EXTENDED RELEASE;ORAL - 75MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons