List of Related Excipient Companies and Suppliers of Diatrizoate Meglumine by Rochem International Inc on PharmaCompass.com

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Chemistry

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Also known as: Meglumine diatrizoate, 131-49-7, Meglumine amidotrizoate, Renografin, Cardiografin, Cystografin
Molecular Formula
C18H26I3N3O9
Molecular Weight
809.1  g/mol
InChI Key
MIKKOBKEXMRYFQ-WZTVWXICSA-N
FDA UNII
3X9MR4N98U

Diatrizoate Meglumine
A versatile contrast medium used for DIAGNOSTIC X-RAY RADIOLOGY.
1 2D Structure

Diatrizoate Meglumine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3,5-diacetamido-2,4,6-triiodobenzoic acid;(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
2.1.2 InChI
InChI=1S/C11H9I3N2O4.C7H17NO5/c1-3(17)15-9-6(12)5(11(19)20)7(13)10(8(9)14)16-4(2)18;1-8-2-4(10)6(12)7(13)5(11)3-9/h1-2H3,(H,15,17)(H,16,18)(H,19,20);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
2.1.3 InChI Key
MIKKOBKEXMRYFQ-WZTVWXICSA-N
2.1.4 Canonical SMILES
CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)NC(=O)C)I.CNCC(C(C(C(CO)O)O)O)O
2.1.5 Isomeric SMILES
CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)NC(=O)C)I.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
3X9MR4N98U
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Amidotricoic Acid

2. Amidotrizoate, Meglumine

3. Angiografin

4. Diatrizoate Methylglucamine

5. Diatrizoate, Meglumine

6. Diatrizoate, Methylglucamine

7. Diatrizoic Acid Methylglucamine

8. Gastrograffin

9. Gastrografin

10. Gastrographin

11. Ioxeol

12. Meglumine Amidotrizoate

13. Meglumine Diatrizoate

14. Meglumine, Diatrizoate

15. Methylglucamine Diatrizoate

16. Methylglucamine, Diatrizoate

17. Methylglucamine, Diatrizoic Acid

18. Reno 60

19. Reno M Dip

20. Reno M-dip

21. Reno Mdip

22. Renograffin

23. Renografin

24. Renografin M 76

25. Renografin M-76

26. Renografin M76

27. Sinografin

28. Triombrast

29. Triombrin

30. Urografin

31. Urografin 76

32. Urovist

33. Verografin

2.3.2 Depositor-Supplied Synonyms

1. Meglumine Diatrizoate

2. 131-49-7

3. Meglumine Amidotrizoate

4. Renografin

5. Cardiografin

6. Cystografin

7. Renovist

8. Renocal

9. Angiovist 282

10. Diatrizoate Methylglucamine

11. Reno

12. Urovist Cysto

13. Urovist Cysto Pediatric

14. Urovist Meglumine Diu/ct

15. Meglumine Amidotrizoate Injection

16. Diatrizoate Meglumine [usp]

17. 131-49-7 (meglumine)

18. Diatrizoic Acid Meglumine Salt

19. 3x9mr4n98u

20. Angiografin

21. Urovist

22. 1-deoxy-1-(methylamino)-d-glucitol 3,5-diacetamido-2,4,6-triiodobenzoate (salt)

23. Renurix

24. Unipaque

25. Hypaque Meglumine

26. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentaol 3,5-diacetamido-2,4,6-triiodobenzoate

27. Cystographin Dilute

28. Diatrizoate Meglumine (usp)

29. Reno-m

30. Reno-m-dip

31. Benzoic Acid, 3,5-bis(acetylamino)-2,4,6-triiodo-, Compd. With 1-deoxy-1-(methylamino)-d-glucitol (1:1)

32. Hypaque 60

33. Renograffin M-76

34. Hypaque M 30

35. Hypaque 13.4

36. Reno-30

37. Hypaque-cysto

38. Reno-dip

39. Cystografin Dilute

40. Reno M 60

41. Gastrografin Oral (veterinary)

42. Reno-60

43. Md 60

44. Einecs 205-024-7

45. Unii-3x9mr4n98u

46. Hypaque (tn)

47. Urovist (tn)

48. Reno (tn)

49. 3,5-bis(acetamido)-2,4,6-triiodbenzoesaeure, 1-desoxy-1-methylamino-d-glucit-salz

50. Benzoic Acid, 3,5-diacetamido-2,4,6-triiodo-, Compd. With 1-deoxy-1-(methylamino)-d-glucitol

51. Schembl107036

52. Chembl1200839

53. Dtxsid20897171

54. Hms2234f23

55. Diatrizoate Meglumine [vandf]

56. Meglumine Amidotrizoate [mart.]

57. Glucitol, 1-deoxy-1-(methylamino)-, 3,5-diacetamido-2,4,6-triiodobenzoate (salt), D-

58. Meglumine Amidotrizoate [who-dd]

59. Diatrizoate Meglumine [green Book]

60. Diatrizoate Meglumine [orange Book]

61. Diatrizoic Acid Meglumine Salt [mi]

62. Diatrizoate Meglumine [usp Monograph]

63. Renocal Component Diatrizoate Meglumine

64. Angiovist Component Diatrizoate Meglumine

65. D02015

66. Meglumine Amidotrizoate Injection [jan]

67. Renovist Component Diatrizoate Meglumine

68. Diatrizoate Meglumine Component Of Renocal

69. Gastrovist Component Diatrizoate Meglumine

70. Renografin Component Diatrizoate Meglumine

71. Sinografin Component Diatrizoate Meglumine

72. Diatrizoate Meglumine Component Of Angiovist

73. Diatrizoate Meglumine Component Of Renovist

74. Gastrografin Component Diatrizoate Meglumine

75. Diatrizoate Meglumine Component Of Gastrovist

76. Diatrizoate Meglumine Component Of Renografin

77. Diatrizoate Meglumine Component Of Sinografin

78. Md-gastroview Component Diatrizoate Meglumine

79. Diatrizoate Meglumine Component Of Gastrografin

80. Q27114690

81. Diatrizoate Meglumine Component Of Md-gastroview

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 809.1 g/mol
Molecular Formula C18H26I3N3O9
Hydrogen Bond Donor Count9
Hydrogen Bond Acceptor Count10
Rotatable Bond Count9
Exact Mass808.8803 g/mol
Monoisotopic Mass808.8803 g/mol
Topological Polar Surface Area209 Ų
Heavy Atom Count33
Formal Charge0
Complexity525
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 6  
Drug NameCystografin
Drug LabelCystografin is a radiopaque contrast agent supplied as a sterile, clear, colorless to pale yellow, mobile or slightly viscous solution. Each mL provides 300 mg diatrizoate meglumine with 0.4 mg edetate disodium as a sequestering agent. Each mL of sol...
Active IngredientDiatrizoate meglumine
Dosage FormSolution
RouteUrethral
Strength30%
Market StatusPrescription
CompanyBracco

2 of 6  
Drug NameCystografin dilute
Drug LabelCystografin Dilute (Diatrizoate Meglumine Injection USP 18%) is a radiopaque contrast agent supplied as a sterile, aqueous solution. Each mL provides 180 mg diatrizoate meglumine with 0.4 mg edetate disodium as a sequestering agent. Each mL of soluti...
Active IngredientDiatrizoate meglumine
Dosage FormSolution
RouteUrethral
Strength18%
Market StatusPrescription
CompanyBracco

3 of 6  
Drug NameSinografin
Drug LabelSinografin (Diatrizoate Meglumine and lodipamide Meglumine Injection) is a sterile, nonpyrogenic, essentially colorless to pale yellow, aqueous radiopaque contrast medium for intrauterine instillation. Each mL provides 527 mg diatrizoate meglumine an...
Active IngredientDiatrizoate meglumine; iodipamide meglumine
Dosage FormSolution
RouteIntrauterine
Strength26.8%; 52.7%
Market StatusPrescription
CompanyBracco

4 of 6  
Drug NameCystografin
Drug LabelCystografin is a radiopaque contrast agent supplied as a sterile, clear, colorless to pale yellow, mobile or slightly viscous solution. Each mL provides 300 mg diatrizoate meglumine with 0.4 mg edetate disodium as a sequestering agent. Each mL of sol...
Active IngredientDiatrizoate meglumine
Dosage FormSolution
RouteUrethral
Strength30%
Market StatusPrescription
CompanyBracco

5 of 6  
Drug NameCystografin dilute
Drug LabelCystografin Dilute (Diatrizoate Meglumine Injection USP 18%) is a radiopaque contrast agent supplied as a sterile, aqueous solution. Each mL provides 180 mg diatrizoate meglumine with 0.4 mg edetate disodium as a sequestering agent. Each mL of soluti...
Active IngredientDiatrizoate meglumine
Dosage FormSolution
RouteUrethral
Strength18%
Market StatusPrescription
CompanyBracco

6 of 6  
Drug NameSinografin
Drug LabelSinografin (Diatrizoate Meglumine and lodipamide Meglumine Injection) is a sterile, nonpyrogenic, essentially colorless to pale yellow, aqueous radiopaque contrast medium for intrauterine instillation. Each mL provides 527 mg diatrizoate meglumine an...
Active IngredientDiatrizoate meglumine; iodipamide meglumine
Dosage FormSolution
RouteIntrauterine
Strength26.8%; 52.7%
Market StatusPrescription
CompanyBracco

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Contrast Media

Substances used to allow enhanced visualization of tissues. (See all compounds classified as Contrast Media.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
X-Ray Contrast Activity [MoA]; Radiographic Contrast Agent [EPC]

API Reference Price

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04-Mar-2024
04-Mar-2024
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DOSAGE - SOLUTION;ORAL, RECTAL - 66%;10%

USFDA APPLICATION NUMBER - 11245

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DOSAGE - SOLUTION;INTRAUTERINE - 52.7%;26.8%

USFDA APPLICATION NUMBER - 11324

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DOSAGE - INJECTABLE;INJECTION - 66%;10%

USFDA APPLICATION NUMBER - 19292

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