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1. Brushite
2. Calcium Monohydrogen Phosphate Dihydrate
3. Calcium Phosphate, Dibasic
4. Calcium Phosphate, Dibasic, Dihydrate
5. Calcium Phosphate, Dihydrate (1:1)
6. Dibasic Calcium Phosphate Dihydrate
7. Dicalcium Phosphate
8. Dicalcium Phosphate Anhydrous
9. Dicalcium Phosphate Dihydrate
1. 7789-77-7
2. Calcium Hydrogenphosphate Dihydrate
3. Dicalcium Phosphate Dihydrate
4. Calcium Monohydrogen Phosphate Dihydrate
5. 14567-92-1
6. Dibasic Calcium Phosphate Dihydrate
7. Calcium Phosphate, Dibasic, Dihydrate
8. Calciumhydrogenphosphatedihydrate
9. D.c.p.
10. Calcium Phosphate Dibasic Dihydrate
11. Calcium;hydrogen Phosphate;dihydrate
12. Calcium Phosphate Dihydrate, Dibasic
13. O7tsz97gep
14. Phosphoric Acid, Calcium Salt (1:1), Dihydrate
15. Dibasic Calcium Phosphate Hydrate
16. Calcium Phosphate Dibasic, Hydrous
17. Calcium Phosphate, Dibasic, Hydrous
18. Brushite
19. Aksepillen
20. Eunova
21. Unii-o7tsz97gep
22. Brushite (ca(hpo4).2h2o)
23. Calcium-hydrogenphosphat-2-wasser
24. Calster (tn)
25. Cahpo4.2h2o
26. Calcium Phosphate Dihydrate, Dibasic [usp:jan]
27. Calcium Phosphate, Gel (aged)
28. Chebi:4496
29. Dibasic Calcium Phosphate (tn)
30. Dtxsid90872536
31. Mfcd00149621
32. Akos015855298
33. Db14481
34. Calcium Hydrogenphosphate Dihydrate,(s)
35. Calcium Hydrogenphosphate--water (1/2)
36. Calcium Hydrogenphosphate Dihydrate, 98%
37. Dibasic Calcium Phosphate Hydrate (jp17)
38. Dicalcium Phosphate Dihydrate [inci]
39. Calcium Phosphate Dihydrate [who-dd]
40. Calcium Phosphate, Dihydrate (1:1)
41. Calcium Phosphate, Dihydrate, Dibasic (usp)
42. Ft-0623398
43. D00937
44. Dibasic Calcium Phosphate Hydrate [jan]
45. Calcium Phosphate, Dibasic, Dihydrate [ii]
46. Calcium Hydrogen Phosphate Dehydrate [who-ip]
47. Calcii Hydrogenophosphas Dihydrate [who-ip Latin]
48. Calcium Hydrogen Phosphate Dihydrate [ep Monograph]
49. Calcium Hydrogenphosphate Dihydrate, P.a., 98.0-105.0%
50. Calcium Hydrogenphosphate Dihydrate, Vetec(tm) Reagent Grade
51. Calcium Phosphate Dihydrate, Dibasic [usp Impurity]
52. Dibasic Calcium Phosphate Dihydrate [usp Monograph]
53. Calcium Phosphate Dibasic Dihydrate, Puriss., Meets Analytical Specification Of Ph. Eur., Bp, Usp, 98-102.5%
| Molecular Weight | 172.09 g/mol |
|---|---|
| Molecular Formula | CaH5O6P |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 0 |
| Exact Mass | 171.9449657 g/mol |
| Monoisotopic Mass | 171.9449657 g/mol |
| Topological Polar Surface Area | 85.4 Ų |
| Heavy Atom Count | 8 |
| Formal Charge | 0 |
| Complexity | 46.5 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 4 |
For use as an over the counter calcium and phosphate supplement, antacid, or a source of calcium and phosphate in toothpaste.
Calcium phosphate reacts with acid in the stomach to raise the pH. In toothpaste it provides a source of calcium and phosphate ions to support remineralization of the teeth. As a supplement it provides a source of calcium and phospate, both of which are important ions in bone homeostasis.
The phosphate ions in calcium phosphate likely react with hydrochloric acid in the stomach to neutralize the pH. In toothpaste and in systemic circulation, calcium phosphate provides a source of calcium and phosphate ions to support remineralization of the teeth and bone homeostasis respectively. The increase in plasma calcium reduces calcium flux from osteocyte activity by reducing the secretion of parathyroid hormone (PTH). Calcium does this by stimulating a G-protein coupled calcium receptor on the surface of parathyroid cells. The reduction in calcium flux increases the amount of calcium deposited in bone resulting in an increase in bone mineral density. The reduction in PTH secretion also reduces the amount of vitamin D metabolized to its active form, calcidiol. Since calcidiol increases the expression of calcium dependent ATPases and transient receptor potential cation channel subfamily V member 6 (TRPV6) both of which are involved in calcium uptake from the gut, a reduction in calcidiol results in less calcium absorption. Additionally, TRPV5, the channel responsible for calcium reabsorption in the kidney, is downregulated when PTH secretion is reduced thus increasing calcium excretion via the kidneys. Another hormone, calitonin, is likely involved in the reduction of bone resorption during periods of high plasma calcium.
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