
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : SZN-8141
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : $175.0 million
Deal Type : Private Placement
Surrozen Secures $175M for Selective Wnt Mimetic Therapies in Eye Diseases
Details : The proceeds from the private placement will used to fund the clinical development of SZN-8141. It is being evaluated for the treatment of age related macular degeneration.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
March 24, 2025
Lead Product(s) : SZN-8141
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : $175.0 million
Deal Type : Private Placement

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Lead Product(s) : Undisclosed
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Discovery
Sponsor : TCGFB
Deal Size : $6.0 million
Deal Type : Collaboration
Surrozen And TCGFB Collaborate on TGF-β Antibodies for Pulmonary Fibrosis
Details : The collaboration aims to discover antibody therapeutics targeting Transforming Growth Factor Beta (TGF-β) for the potential treatment of patients with idiopathic pulmonary fibrosis (IPF).
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 04, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Discovery
Sponsor : TCGFB
Deal Size : $6.0 million
Deal Type : Collaboration

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Lead Product(s) : SZN-413
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Sponsor : Boehringer Ingelheim GmbH
Deal Size : $599.0 million
Deal Type : Collaboration
Surrozen Earns $10 Million Milestone Payment in Retinal Diseases Collaboration
Details : Surrozen collaborates with Boehringer to research & develop SZN-413 to treat retinal diseases and will receive an exclusive, worldwide license to develop other Fzd4-specific Wnt-modulating molecules.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : $12.5 million
September 24, 2024
Lead Product(s) : SZN-413
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Sponsor : Boehringer Ingelheim GmbH
Deal Size : $599.0 million
Deal Type : Collaboration

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Lead Product(s) : SZN-043
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Surrozen Begins Phase 1b Trial of SZN-043 for Severe Alcohol-Associated Hepatitis
Details : SZN-043 is a hepatocyte-targeted R-spondin mimetic, monoclonal antibody. It is being evaluated for the treatment of alcohol-associated hepatitis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
June 04, 2024
Lead Product(s) : SZN-043
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : SZN-043
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Surrozen Announces Safety, Pharmacodynamic and Liver Function Data for SZN-043
Details : SZN-043 is a hepatocyte-targeted R-spondin mimetic, monoclonal antibody. It is being evaluated for the treatment of severe liver diseases, initially focusing on alcohol-associated hepatitis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
April 01, 2024
Lead Product(s) : SZN-043
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : SZN-043
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase I
Sponsor : RA Capital Management
Deal Size : $192.5 million
Deal Type : Private Placement
Surrozen Announces $192.5 Million Private Placement Priced At Market Under Nasdaq Rules
Details : SZN-043 proceeds will expand Phase 1b trials for treating severe alcohol-associated hepatitis, furthering clinical development for the company's innovative treatment pipeline.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
April 01, 2024
Lead Product(s) : SZN-043
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase I
Sponsor : RA Capital Management
Deal Size : $192.5 million
Deal Type : Private Placement

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Lead Product(s) : SZN-043
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SZN-043, an R-Spondin mimetic by enhancing Wnt signaling in a cell-targeted manner, in preclinical data it showed rapid, transient increases in hepatocyte proliferation and was well tolerated in non-clinical toxicology studies.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
October 10, 2022
Lead Product(s) : SZN-043
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : SZN-413
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Preclinical
Sponsor : Boehringer Ingelheim GmbH
Deal Size : $599.0 million
Deal Type : Collaboration
Details : Under the terms of the agreement, Boehringer Ingelheim will receive an exclusive, worldwide license to develop SZN-413 and other Fzd4-specific Wnt-modulating molecules for all purposes, including as a treatment for retinal diseases.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : $12.5 million
October 06, 2022
Lead Product(s) : SZN-413
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Preclinical
Sponsor : Boehringer Ingelheim GmbH
Deal Size : $599.0 million
Deal Type : Collaboration

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Lead Product(s) : SZN-413
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SZN-413, a bi-specific antibody that targets FZD4 and LRP5, induced Wnt signaling and upregulated blood-retinal barrier gene expression in retinal ECs. SZN-413 reduced the pathologic neovascularization area size compared to vehicle and comparable to the ...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
September 26, 2022
Lead Product(s) : SZN-413
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : SZN-043
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Surrozen Initiates Dosing in Phase 1 Clinical Trial of SZN-043 for Severe Alcoholic Hepatitis
Details : In preclinical models of liver injury and fibrosis, SZN-043 has been shown to selectively activate Wnt signaling, stimulate transient hepatocyte proliferation, improve liver function and reduce fibrosis with no treatment-related adverse effects observed ...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
June 13, 2022
Lead Product(s) : SZN-043
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
