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    [{"orgOrder":0,"company":"ALMATICA PHARMA INC","sponsor":"TWi Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Acquisition","leadProduct":"Lisinopril","moa":"||ACE receptor","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"ALMATICA PHARMA INC","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"ALMATICA PHARMA INC \/ TWi Pharmaceuticals","highestDevelopmentStatusID":"15","companyTruncated":"ALMATICA PHARMA INC \/ TWi Pharmaceuticals"},{"orgOrder":0,"company":"Alvogen","sponsor":"AZTIQ PHARMA","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Acquisition","leadProduct":"Lisinopril","moa":"||ACE receptor","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Alvogen","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Alvogen \/ AZTIQ PHARMA","highestDevelopmentStatusID":"15","companyTruncated":"Alvogen \/ AZTIQ PHARMA"},{"orgOrder":0,"company":"Yiling Pharmaceutical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CHINA","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Lisinopril","moa":"||ACE receptor","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Yiling Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Yiling Pharmaceutical \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Yiling Pharmaceutical \/ Inapplicable"},{"orgOrder":0,"company":"AstraZeneca","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Sodium Zirconium Cyclosilicate","moa":"||Potassium","graph1":"Nephrology","graph2":"Phase III","graph3":"AstraZeneca","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Suspension","sponsorNew":"AstraZeneca \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"AstraZeneca \/ Inapplicable"},{"orgOrder":0,"company":"Northwell Health","sponsor":"Lupus Research Alliance","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Lisinopril","moa":"||Angiotensin-converting enzyme","graph1":"Immunology","graph2":"Phase II","graph3":"Northwell Health","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Northwell Health \/ Lupus Research Alliance","highestDevelopmentStatusID":"8","companyTruncated":"Northwell Health \/ Lupus Research Alliance"},{"orgOrder":0,"company":"Merck & Co","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Warfarin Sodium","moa":"||Vitamin k epoxide reductase complex subunit 1 isoform 1","graph1":"Undisclosed","graph2":"Phase I","graph3":"Merck & Co","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Oral","sponsorNew":"Merck & Co \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Merck & Co \/ Inapplicable"},{"orgOrder":0,"company":"Pharmtechnology","sponsor":"ClinPharmInvest","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"BELARUS","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Lisinopril","moa":"||Angiotensin-converting enzyme","graph1":"Undisclosed","graph2":"Phase I","graph3":"Pharmtechnology","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Pharmtechnology \/ ClinPharmInvest","highestDevelopmentStatusID":"6","companyTruncated":"Pharmtechnology \/ ClinPharmInvest"}]

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                            01

                            Merck & Co

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Merck & Co

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Warfarin Sodium,Enlicitide Decanoate,Lisinopril

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of Enlicitide Decanoate (MK-0616), Warfarin, and Lisinopril in Healthy Adult Participants (MK-0616-026...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 14, 2025

                            Lead Product(s) : Warfarin Sodium,Enlicitide Decanoate,Lisinopril

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            ALMATICA PHARMA INC

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            ALMATICA PHARMA INC

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : TWi Pharmaceuticals

                            Deal Size : $38.5 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Bora Acquires Six US Brand Product Licenses, Rights

                            Details : Through the acquisition, Bora will utilize Almatica's generic pharmaceutical products, including Zestril (lisinopril), an oral tablet used for treating hypertension, for commercialization purposes.

                            Product Name : Zestril

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            August 18, 2023

                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : TWi Pharmaceuticals

                            Deal Size : $38.5 million

                            Deal Type : Acquisition

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                            03

                            Pharmtechnology

                            Belarus arrow
                            EPSC
                            Not Confirmed

                            Pharmtechnology

                            Belarus arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : ClinPharmInvest

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bioequivalence Study of Two Formulations of Lisinopril Tablet 20 mg in Healthy Volunteers Under Fasting Condit...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 30, 2021

                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : ClinPharmInvest

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            AstraZeneca

                            United Kingdom arrow
                            EPSC
                            Not Confirmed

                            AstraZeneca

                            United Kingdom arrow
                            EPSC
                            Not Confirmed
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                            • EDQM
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                            Lead Product(s) : Sodium Zirconium Cyclosilicate,Lisinopril,Valsartan,Irbesartan

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression i...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 24, 2021

                            Lead Product(s) : Sodium Zirconium Cyclosilicate,Lisinopril,Valsartan,Irbesartan

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Alvogen

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Alvogen

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : AZTIQ PHARMA

                            Deal Size : $350.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Aztiq Buys 17% Stake in Alvogen US

                            Details : Zestril (lisinopril) belongs to a class of drugs known as ACE inhibitors. It works by relaxing blood vessels so blood can flow more easily. Zestril is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old.

                            Product Name : Zestril

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            June 30, 2021

                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : AZTIQ PHARMA

                            Deal Size : $350.0 million

                            Deal Type : Acquisition

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                            06

                            Yiling Pharmaceutical

                            China arrow
                            EPSC
                            Not Confirmed

                            Yiling Pharmaceutical

                            China arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Preparation Products of Yiling Pharma Approved by FDA for Launch in the US Market

                            Details : The announcement showed that Lisinopril Tablets are mainly used for the treatment of essential hypertension (EH) and renal vascular hypertension (RVH) and were originally researched and developed by Astrazeneca and approved for launch in the United State...

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 19, 2020

                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Northwell Health

                            Country arrow
                            EPSC
                            Not Confirmed

                            Northwell Health

                            Country arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : Lupus Research Alliance

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Centrally Acting ACE Inhibition in SLE

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 24, 2020

                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : Lupus Research Alliance

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Bright Future Pharma Lab

                            Hong Kong arrow
                            EPSC
                            Not Confirmed

                            Bright Future Pharma Lab

                            Hong Kong arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Lisinopril

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Chinese University of Hong Kong

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Clinical Bioequivalence Study on Two Lisinopril Tablets 20mg Formulations

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 26, 2018

                            Lead Product(s) : Lisinopril

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Chinese University of Hong Kong

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Ascension Health

                            Country arrow
                            EPSC
                            Not Confirmed

                            Ascension Health

                            Country arrow
                            EPSC
                            Not Confirmed
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                            • EDQM
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                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Prophylactic Lisinopril to Prevent Anthracycline Cardiomyopathy.

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 08, 2018

                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Vanderbilt University Medical Center

                            Country arrow
                            EPSC
                            Not Confirmed

                            Vanderbilt University Medical Center

                            Country arrow
                            EPSC
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : National Institute of Diabetes and Digestive and Kidney Diseases | Aminu Kano Teaching Hospital | Frederick National Laboratory | Brigham and Women's Hospital

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Optimal Management of HIV Infected Adults at Risk for Kidney Complications in Nigeria

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 28, 2017

                            Lead Product(s) : Lisinopril,Inapplicable

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : National Institute of Diabetes and Digestive and Kidney Diseases | Aminu Kano Teaching Hospital | Frederick National Laboratory | Brigham and Women's Hospital

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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