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    [{"orgOrder":0,"company":"Weill Medical College of Cornell University","sponsor":"Children's Hospital Colorado | SLC6A1 Connect | STXBP1 Foundation | Clara Inspired | University of Pennsylvania Orphan Disease Center | Horizon Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Glycerol Phenylbutyrate","moa":"Glutamine","graph1":"Neurology","graph2":"Phase I","graph3":"Weill Medical College of Cornell University","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Weill Medical College of Cornell University \/ Children's Hospital Colorado | SLC6A1 Connect | STXBP1 Foundation | Clara Inspired | University of Pennsylvania Orphan Disease Center | Horizon Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Weill Medical College of Cornell University \/ Children's Hospital Colorado | SLC6A1 Connect | STXBP1 Foundation | Clara Inspired | University of Pennsylvania Orphan Disease Center | Horizon Therapeutics"}]

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    Glycerol Phenylbutyrate

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                            01

                            Weill Medical College of Cornell University

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                            Peptide Process CMC
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                            Weill Medical College of Cornell University

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                            Peptide Process CMC
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                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Children's Hospital Colorado | SLC6A1 Connect | STXBP1 Foundation | Clara Inspired | University of Pennsylvania Orphan Disease Center | Horizon Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 23, 2021

                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Children's Hospital Colorado | SLC6A1 Connect | STXBP1 Foundation | Clara Inspired | University of Pennsylvania Orphan Disease Center | Horizon Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Amgen Inc

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                            Peptide Process CMC
                            Not Confirmed

                            Amgen Inc

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                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of Glycerol Phenylbutyrate & Sodium Phenylbutyrate in Phenylbutyrate Naïve Patients With Urea Cycle D...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 07, 2017

                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            National Jewish Health

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                            Peptide Process CMC
                            Not Confirmed

                            National Jewish Health

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                            Peptide Process CMC
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                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : University of Alabama at Birmingham | Children's Hospital of Philadelphia | Johns Hopkins University | Amgen Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Glycerol Phenylbutyrate Corrector Therapy For CF (Cystic Fibrosis)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 23, 2014

                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : University of Alabama at Birmingham | Children's Hospital of Philadelphia | Johns Hopkins University | Amgen Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Amgen Inc

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                            Peptide Process CMC
                            Not Confirmed

                            Amgen Inc

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                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 ...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 22, 2014

                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            The University of Pittsburgh School of Medicine

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                            Peptide Process CMC
                            Not Confirmed

                            The University of Pittsburgh School of Medicine

                            U.S.A arrow
                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Amgen Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Use of Ravictiâ„¢ in Patients With MCAD Deficiency With the 985A>G (K304E) Mutation

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 20, 2013

                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Amgen Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Amgen Inc

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                            Peptide Process CMC
                            Not Confirmed

                            Amgen Inc

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                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of the Safety, Pharmacokinetics and Efficacy of HPN-100, in Pediatric Subjects With Urea Cycle Disorders...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 04, 2011

                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Amgen Inc

                            U.S.A arrow
                            Peptide Process CMC
                            Not Confirmed

                            Amgen Inc

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                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            To Evaluate the Safety of Long-term Use of HPN-100 in the Management of Urea Cycle Disorders (UCDs)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 10, 2010

                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Amgen Inc

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                            Peptide Process CMC
                            Not Confirmed

                            Amgen Inc

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                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Pharmacology/Toxicology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Double-Blind Randomized Crossover Trial to Access Electrocardiogram Effects of HPN-100

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 03, 2010

                            Lead Product(s) : Glycerol Phenylbutyrate

                            Therapeutic Area : Pharmacology/Toxicology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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