
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : D-Fi
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Prosoft Clinical
Deal Size : Inapplicable
Deal Type : Inapplicable
Evaluation of D-Fi for the Treatment of Wounds Due to DEB
Details : D-Fi is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Epidermolysis Bullosa Dystrophica.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
March 25, 2025
Lead Product(s) : D-Fi
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Prosoft Clinical
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : LV-FAH
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Paragon Biosciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The preclinical research demonstrated that lentiviral vector gene therapy LV-FAH was active in a large animal model of HT1 and the pigs did not experience adverse events from the integrating vector.
Product Name : LV-FAH
Product Type : Enzyme
Upfront Cash : Inapplicable
August 30, 2022
Lead Product(s) : LV-FAH
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Paragon Biosciences
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Dabocemagene Autoficel
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : US Food & Drug Administration
Deal Size : $1.8 million
Deal Type : Funding
Details : The grant supports a meaningful portion of the Phase 3 clinical development of dabocemagene autoficel (FCX-007, D-Fi), an investigational gene therapy for the treatment of recessive dystrophic epidermolysis bullosa (RDEB).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
October 21, 2021
Lead Product(s) : Dabocemagene Autoficel
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : US Food & Drug Administration
Deal Size : $1.8 million
Deal Type : Funding

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Lead Product(s) : Dabocemagene Autoficel
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : first patient has been dosed in the DeFi-RDEB Phase 3 clinical trial evaluating debcoemagene autoficel (D-Fi), the company’s lead gene therapy candidate formerly designated FCX-007, in recessive dystrophic epidermolysis bullosa (RDEB).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
October 28, 2020
Lead Product(s) : Dabocemagene Autoficel
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : FCX-013,Veledimex
Therapeutic Area : Dermatology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The open label, single cohort Phase 1/2 clinical trial is evaluating the safety of FCX-013 as its primary objective. Secondary objectives include assessments of fibrosis at targeted sclerotic lesions at various time points through 26 weeks post-administr...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
October 15, 2020
Lead Product(s) : FCX-013,Veledimex
Therapeutic Area : Dermatology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Dabocemagene Autoficel
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Fidelity Management & Research Company
Deal Size : $55.0 million
Deal Type : Funding
Castle Creek Biosciences Announces $75 Million Investment
Details : The company plans to use the funding to advance and expand its gene therapy pipeline, led by the Phase 3 clinical development of FCX-007.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
March 25, 2020
Lead Product(s) : Dabocemagene Autoficel
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Fidelity Management & Research Company
Deal Size : $55.0 million
Deal Type : Funding

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Lead Product(s) : Dabocemagene Autoficel
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa
Details : Dabocemagene Autoficel is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Epidermolysis Bullosa Dystrophica.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
December 30, 2019
Lead Product(s) : Dabocemagene Autoficel
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : FCX-013
Therapeutic Area : Dermatology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : FCX-013 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Scleroderma, Localized.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
November 14, 2018
Lead Product(s) : FCX-013
Therapeutic Area : Dermatology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Diacerein
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A 4-Day Study to Evaluate the Photoxicity of Diacerein 1% Topical Ointment in Healthy Volunteers
Details : Diacerein is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 22, 2018
Lead Product(s) : Diacerein
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Diacerein
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Diacerein is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 22, 2018
Lead Product(s) : Diacerein
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
