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    4CH-018336

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    4CH-018336
    Also known as: 764667-65-4, (2z)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8h)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one, 1-[3-(trifluoromethyl)-6,8-dihydro-5h-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione, Sitagliptin keto amide, Sitagliptin impurity 13, Czz5uj9mj6
    Molecular Formula
    C16H12F6N4O2
    Molecular Weight
    406.28  g/mol
    InChI Key
    QAEDTLFWHIEVPK-UHFFFAOYSA-N
    FDA UNII
    CZZ5UJ9MJ6
    1 2D Structure

    4CH-018336

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione
    2.1.2 InChI
    InChI=1S/C16H12F6N4O2/c17-10-6-12(19)11(18)4-8(10)3-9(27)5-14(28)25-1-2-26-13(7-25)23-24-15(26)16(20,21)22/h4,6H,1-3,5,7H2
    2.1.3 InChI Key
    QAEDTLFWHIEVPK-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)CC(=O)CC3=CC(=C(C=C3F)F)F
    2.2 Other Identifiers
    2.2.1 UNII
    CZZ5UJ9MJ6
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 764667-65-4

    2. (2z)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8h)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

    3. 1-[3-(trifluoromethyl)-6,8-dihydro-5h-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione

    4. Sitagliptin Keto Amide

    5. Sitagliptin Impurity 13

    6. Czz5uj9mj6

    7. Mfcd11111443

    8. 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8h)-yl]-4-(2,4,5-trifluorophenyl)-1,3-butanedione

    9. 4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8h)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

    10. 4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8h)-yl]-1-(2,4,5-trifluorop

    11. 1,3-butanedione, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8h)-yl]-4-(2,4,5-trifluorophenyl)-

    12. 1-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8h)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione

    13. 1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8h)-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione

    14. 4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8h)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

    15. Rac-sitagliptin 3-ketone

    16. (2z)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8h)-yl)-1-(2,4,5-trifluorophenyl)butan-2-one

    17. 1,3-butanedione, 1-(5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyrazin-7(8h)-yl)-4-(2,4,5-trifluorophenyl)-

    18. 1-(3-(trifluoromethyl)-5,6-dihydro-(1,2,4)triazolo(4,3-a)pyrazin-7(8h)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione

    19. Cid 9887588

    20. Sitagliptin Impurity 42

    21. Unii-czz5uj9mj6

    22. Ec 619-997-4

    23. Prositagliptin Ketone

    24. Schembl214373

    25. Sitagliptin Ketoamide Impurity

    26. Dtxsid50432418

    27. Bcp22636

    28. Zinc22065541

    29. Akos015918077

    30. Sitagliptin Keto Amide Impurity

    31. Bcp9000168

    32. Ac-22606

    33. Ds-13885

    34. Sy005503

    35. Db-075134

    36. Am20090689

    37. Cs-0165427

    38. Ft-0673406

    39. F20432

    40. 667o654

    41. 4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8h)-yl]

    42. (2z)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8h)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

    43. (2z)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine -7(8h)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

    44. (2z)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8h)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one?

    45. 1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8h)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione? (sitagliptin Impurity Pound(c)

    46. 3-(trifluoromethyl)-7-[1,3-dioxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine

    47. 4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazin-7(8h)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

    48. 4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8h)-yl]-1-(2,4,5-trifluoroph

    49. 4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-alpha]pyrazin-7(8h)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

    50. 7-(1,3-dioxo-4-(2,4,5-trifluorophenyl)-butyl)-3-trifluoromethyl-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine

    51. 7-(1,3-dioxo-4-(2,4,5-trifluorophenyl)butyl)-3-trifluoromethyl-5,6,7,8-tetrahydro-1,2,4-triazolo(4,3-a)pyrazine

    2.4 Create Date
    2006-10-25
    3 Chemical and Physical Properties
    Molecular Weight 406.28 g/mol
    Molecular Formula C16H12F6N4O2
    XLogP31.1
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count10
    Rotatable Bond Count4
    Exact Mass406.08644461 g/mol
    Monoisotopic Mass406.08644461 g/mol
    Topological Polar Surface Area68.1 Ų
    Heavy Atom Count28
    Formal Charge0
    Complexity606
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
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                                  3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[...

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                                  762240-92-6
                                  Sitagliptin Phosphate
                                  Lofty Laboratories was founded in 2005 with a focus on creating an impact in pharmaceutics value chain. T...
                                  Lofty Laboratories was founded in 2005 with a focus on creating an impact in pharmaceutics value chain. Today we are a leading pharmaceutical bulk drug manufacturer of Intermediates, Advanced Intermediates. Innovation has been forefront of our approach, powered by highly qualified teams and the use of cutting-edge technology. We are a USFDA-approved (USFDA FEI No: 3014053359) company and are continuously expanding our product portfolio and our business to international markets.
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                                  Lofty Laboratories

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                                    (3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2...

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                                    486460-32-6
                                    Sitagliptin Phosphate
                                    Lofty Laboratories was founded in 2005 with a focus on creating an impact in pharmaceutics value chain. T...
                                    Lofty Laboratories was founded in 2005 with a focus on creating an impact in pharmaceutics value chain. Today we are a leading pharmaceutical bulk drug manufacturer of Intermediates, Advanced Intermediates. Innovation has been forefront of our approach, powered by highly qualified teams and the use of cutting-edge technology. We are a USFDA-approved (USFDA FEI No: 3014053359) company and are continuously expanding our product portfolio and our business to international markets.
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                                    Luna Chemicals

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                                      BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID

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                                      486460-00-8
                                      Sitagliptin Phosphate
                                      LUNA Chemicals Co.,Ltd. markets and manufactures world-class quality Active Pharmaceutical Ingredients an...
                                      LUNA Chemicals Co.,Ltd. markets and manufactures world-class quality Active Pharmaceutical Ingredients and intermediate chemicals for generic pharmaceutical companies. Our Development Team focus strategically on the core therapeutic areas: cardiovascular, anti-depressant, allergic, healthcare and plant extraction. We provide technical support and efficient regulatory documentation for manufacturers, intellectual property(IP) was always carefully considered as well. We also provide excellent outsourcing services to customers and laboratory support.
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                                      Luna Chemicals

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                                        3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[...

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                                        762240-92-6
                                        Sitagliptin Phosphate
                                        LUNA Chemicals Co.,Ltd. markets and manufactures world-class quality Active Pharmaceutical Ingredients an...
                                        LUNA Chemicals Co.,Ltd. markets and manufactures world-class quality Active Pharmaceutical Ingredients and intermediate chemicals for generic pharmaceutical companies. Our Development Team focus strategically on the core therapeutic areas: cardiovascular, anti-depressant, allergic, healthcare and plant extraction. We provide technical support and efficient regulatory documentation for manufacturers, intellectual property(IP) was always carefully considered as well. We also provide excellent outsourcing services to customers and laboratory support.
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                                        Nanjing Joyin Pharmachem Co, ltd

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                                          2,4,5-trifluoromethyl phenyl acetic acid

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                                          209995-38-0
                                          Sitagliptin Phosphate
                                          We specialize in the supply of API and API related intermediates and services. A significant part of our ...
                                          We specialize in the supply of API and API related intermediates and services. A significant part of our business comes from the process/production development tailored to our customers' requirement.We see our core-value in our top-of-the-rank R&D capabilities, strict quality system, fast communication with accuracy and 15years of continued dedication to pharmaceutical and chemical industries.We take pride in the long term partnership with our reputed customers, and feel truly fortunate to work with mutual and respect. We constantly strive to keep up with their ever increasing expectation, to ensure we are worthy of their trust and reliance.
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                                          Nanjing Joyin Pharmachem Co, ltd

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                                            3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[...

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                                            762240-14-6
                                            Sitagliptin Phosphate
                                            We specialize in the supply of API and API related intermediates and services. A significant part of our ...
                                            We specialize in the supply of API and API related intermediates and services. A significant part of our business comes from the process/production development tailored to our customers' requirement.We see our core-value in our top-of-the-rank R&D capabilities, strict quality system, fast communication with accuracy and 15years of continued dedication to pharmaceutical and chemical industries.We take pride in the long term partnership with our reputed customers, and feel truly fortunate to work with mutual and respect. We constantly strive to keep up with their ever increasing expectation, to ensure we are worthy of their trust and reliance.
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                                            Nanjing Joyin Pharmachem Co, ltd

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                                              Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acidÂ...

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                                              486460-00-8
                                              Sitagliptin Phosphate
                                              We specialize in the supply of API and API related intermediates and services. A significant part of our ...
                                              We specialize in the supply of API and API related intermediates and services. A significant part of our business comes from the process/production development tailored to our customers' requirement.We see our core-value in our top-of-the-rank R&D capabilities, strict quality system, fast communication with accuracy and 15years of continued dedication to pharmaceutical and chemical industries.We take pride in the long term partnership with our reputed customers, and feel truly fortunate to work with mutual and respect. We constantly strive to keep up with their ever increasing expectation, to ensure we are worthy of their trust and reliance.
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                                              Nanjing Lift Pharmaceutical Technol...

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                                                (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5,-trifluorophe...

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                                                486460-00-8
                                                Sitagliptin Phosphate
                                                Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and ...
                                                Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and technical service of APIs, pharmaceutical intermediates and specialty chemicals. The marketing department is located in Nanjing. We have two GMP facilities in Jiangsu Province and cooperative factories in Zhejiang Province. The leading products range of the company is oncology and anti-diabetes . We also specialize in custom synthesis and contract research which demonstrates our state-of-the-art technology and capacity of synthesis.
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                                                Nanjing Lift Pharmaceutical Technol...

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                                                  3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo(...

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                                                  762240-92-6
                                                  Sitagliptin Phosphate
                                                  Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and ...
                                                  Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and technical service of APIs, pharmaceutical intermediates and specialty chemicals. The marketing department is located in Nanjing. We have two GMP facilities in Jiangsu Province and cooperative factories in Zhejiang Province. The leading products range of the company is oncology and anti-diabetes . We also specialize in custom synthesis and contract research which demonstrates our state-of-the-art technology and capacity of synthesis.
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                                                  Nantong Chem-land

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                                                    2,4,5-Trifluorophenylacetic acid

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                                                    209995-38-0
                                                    Sitagliptin Phosphate
                                                    Nantong Chem-land Co., Ltd. is located in Nantong city, a developed port city which distance from Shangha...
                                                    Nantong Chem-land Co., Ltd. is located in Nantong city, a developed port city which distance from Shanghai is only 1.5 hours by car. Established in 2006, we have developed quickly into a comprehensive entity engaged in and marketing, developing and manufacturing of Active Pharmaceutical Ingredients, intermediates and fine chemicals.Our collaboration production site is in the national chemical park in our city: Nantong Rudong Yangkou Chemical park. Available test instrument in the production site: IR, UV, HPLC, GC, etc.. Production equipment: More than 50 reactors, size from 1L to 3000L , reaction temperature from -10℃ to +300℃.
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                                                    Nantong Chem-land

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                                                      3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[...

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                                                      762240-92-6
                                                      Sitagliptin Phosphate
                                                      Nantong Chem-land Co., Ltd. is located in Nantong city, a developed port city which distance from Shangha...
                                                      Nantong Chem-land Co., Ltd. is located in Nantong city, a developed port city which distance from Shanghai is only 1.5 hours by car. Established in 2006, we have developed quickly into a comprehensive entity engaged in and marketing, developing and manufacturing of Active Pharmaceutical Ingredients, intermediates and fine chemicals.Our collaboration production site is in the national chemical park in our city: Nantong Rudong Yangkou Chemical park. Available test instrument in the production site: IR, UV, HPLC, GC, etc.. Production equipment: More than 50 reactors, size from 1L to 3000L , reaction temperature from -10℃ to +300℃.
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                                                      Nantong Chem-land

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                                                        Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid

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                                                        486460-00-8
                                                        Sitagliptin Phosphate
                                                        Nantong Chem-land Co., Ltd. is located in Nantong city, a developed port city which distance from Shangha...
                                                        Nantong Chem-land Co., Ltd. is located in Nantong city, a developed port city which distance from Shanghai is only 1.5 hours by car. Established in 2006, we have developed quickly into a comprehensive entity engaged in and marketing, developing and manufacturing of Active Pharmaceutical Ingredients, intermediates and fine chemicals.Our collaboration production site is in the national chemical park in our city: Nantong Rudong Yangkou Chemical park. Available test instrument in the production site: IR, UV, HPLC, GC, etc.. Production equipment: More than 50 reactors, size from 1L to 3000L , reaction temperature from -10℃ to +300℃.
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                                                        Ningbo Zhenlei Chemical Co.,Ltd

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                                                          3-(Trifluoromethyl)-5,6,7,8-tetrahydro- [1,2,4]triazolo...

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                                                          762240-92-6
                                                          Sitagliptin Phosphate
                                                          Ningbo Zhenlei Chemical Co.,ltd. located in ningbo city, zhejiang province. We are specializes in R&D, ma...
                                                          Ningbo Zhenlei Chemical Co.,ltd. located in ningbo city, zhejiang province. We are specializes in R&D, manufacturing and marketing. Our main product is R-3-amino-1-butanol, Sitagliptin, Sitagliptin phosphate monohydrate. With strong experience and network in Pharmaceutical and Agrochemical, across the globe, Zhenlei is your ideal partner for development of multi-scale synthesis projects as well as manufacturing activities, by ensuring reliable sourcing of raw materials, at competitive pricing and suitable packaging.
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                                                          Ningbo Zhenlei Chemical Co.,Ltd

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                                                            Sitagliptin free base

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                                                            486460-32-6
                                                            Sitagliptin Phosphate
                                                            Ningbo Zhenlei Chemical Co.,ltd. located in ningbo city, zhejiang province. We are specializes in R&D, ma...
                                                            Ningbo Zhenlei Chemical Co.,ltd. located in ningbo city, zhejiang province. We are specializes in R&D, manufacturing and marketing. Our main product is R-3-amino-1-butanol, Sitagliptin, Sitagliptin phosphate monohydrate. With strong experience and network in Pharmaceutical and Agrochemical, across the globe, Zhenlei is your ideal partner for development of multi-scale synthesis projects as well as manufacturing activities, by ensuring reliable sourcing of raw materials, at competitive pricing and suitable packaging.
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                                                            Ningbo Zhenlei Chemical Co.,Ltd

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                                                              2,4,5-Trifluorophenylacetic acid

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                                                              209995-38-0
                                                              Sitagliptin Phosphate
                                                              Ningbo Zhenlei Chemical Co.,ltd. located in ningbo city, zhejiang province. We are specializes in R&D, ma...
                                                              Ningbo Zhenlei Chemical Co.,ltd. located in ningbo city, zhejiang province. We are specializes in R&D, manufacturing and marketing. Our main product is R-3-amino-1-butanol, Sitagliptin, Sitagliptin phosphate monohydrate. With strong experience and network in Pharmaceutical and Agrochemical, across the globe, Zhenlei is your ideal partner for development of multi-scale synthesis projects as well as manufacturing activities, by ensuring reliable sourcing of raw materials, at competitive pricing and suitable packaging.
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                                                              Ningbo Zhenlei Chemical Co.,Ltd

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                                                                (R)-3-(tert-butoxycarbonyl)-4-(2,4,5- trifluorophenyl)b...

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                                                                486460-00-8
                                                                Sitagliptin Phosphate
                                                                Ningbo Zhenlei Chemical Co.,ltd. located in ningbo city, zhejiang province. We are specializes in R&D, ma...
                                                                Ningbo Zhenlei Chemical Co.,ltd. located in ningbo city, zhejiang province. We are specializes in R&D, manufacturing and marketing. Our main product is R-3-amino-1-butanol, Sitagliptin, Sitagliptin phosphate monohydrate. With strong experience and network in Pharmaceutical and Agrochemical, across the globe, Zhenlei is your ideal partner for development of multi-scale synthesis projects as well as manufacturing activities, by ensuring reliable sourcing of raw materials, at competitive pricing and suitable packaging.
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                                                                Octane Laboratories

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                                                                  3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[...

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                                                                  762240-92-6
                                                                  Sitagliptin Phosphate
                                                                  OctaneX Labs is a leading intermediates and Active Pharmaceutical Ingredients (API) manufacturing company...
                                                                  OctaneX Labs is a leading intermediates and Active Pharmaceutical Ingredients (API) manufacturing company specializing in the development of innovative processes for the synthesis of a wide range of products. We also undertake custom pharmaceutical services and contract Research Synthesis. We are commited to create better quality of life by being at the forefront of research, manufacturing and marketing of high quality API'S.As a growing organization, we are aware that we can’t achieve our goals singly. We collaborate and work in unison with a large number of reputed and like-minded partners
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                                                                  Prajna Generics

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                                                                    (Z)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro- [1,2,4]...

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                                                                    767340-03-4
                                                                    Sitagliptin Phosphate
                                                                    Prajna is an innovation driven pharmaceutical company. We dedicated to Research, Process development and ...
                                                                    Prajna is an innovation driven pharmaceutical company. We dedicated to Research, Process development and Manufacturing APIs and Advanced Intermediates for Active Pharmaceutical Ingredients (APIs) for the global pharmaceutical companies. It provides value-added services in Contract Research, Custom Synthesis, and Specialties Scientific technology (Green Process, APIs Process Development, Polymorphism, Crystallisation and Purification) for Pharmaceutical and Life Sciences industry.
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                                                                    Sagar Life Sciences

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                                                                      1-Ethyl-3-(3-Dimethylaminopropyl)- Carbodiimide Hydroch...

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                                                                      25952-53-8
                                                                      Sitagliptin Phosphate
                                                                      We are a top producer of Pharmaceutical Intermediates, Specialty Chemicals, and More, with origins dating...
                                                                      We are a top producer of Pharmaceutical Intermediates, Specialty Chemicals, and More, with origins dating back to 1998. Globally renowned for its Organic Compounds, Inorganic Compounds, Industrial Acids, Industrial Chemicals, Zinc Acetates, Calcium Chloride Dihydrates, Speciality Chemicals, and other products, Sagar Life Science Private Limited is a customer-centric business with a primary focus on innovations, quality, and customization. Since sustainability is among our core values, we concentrate on improving the efficiency of our processes to manufacture sustainable results.
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                                                                      Sanpra Synthesis

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                                                                        2,2-Dimetyl-1,3-Dioxane-4,6- Dione(Meldrum’s Acid)

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                                                                        2033-24-1
                                                                        Sitagliptin Phosphate
                                                                        Sanpra Synthesis strongly believes that with its expertise and innovative pharmaceutical business backgro...
                                                                        Sanpra Synthesis strongly believes that with its expertise and innovative pharmaceutical business background, it is aptly positioned for APIs and intermediates manufacturing and outsourcing for the global market. We also undertake custom synthesis and contract manufacturing. Setting up multiple c GMP-manufacturing facility and world-class R&D center located in Vizag APSEZ De-notified area with well connected to road, rail, and air enabling cargo movement to the nearest transport facility in commercial production from January 2020.
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                                                                        Smilax Laboratories Limited

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                                                                        • EDQM
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                                                                        3-(Trifluoromethyl)-5,6,7,8-tetrahydro- [1,2,4] triazol...

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                                                                        762240-92-6
                                                                        Sitagliptin Phosphate
                                                                        Smilax Laboratories Limited is a research-driven, vertically integrated pharmaceutical company manufactur...
                                                                        Smilax Laboratories Limited is a research-driven, vertically integrated pharmaceutical company manufacturing Active Pharmaceutical Ingredients, API Intermediates and NDDS/Pellets for the generics market across the world. Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today. Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today.Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today. Smilax manufactures APIs and API Intermediates at its state-of-the-art manufacturing facilities located at Hyderabad, Telangana and Visakhapatnam, Andhra Pradesh, India. Supported by a highly qualified and competent technical team, and endowed with strengths in research and development, Smilax continues to expand its presence in the world of pharmaceuticals.
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                                                                        SS Pharma

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                                                                          Methly 3-Oxo-4-(2,4,5-Trifluorophenly)Butanoate

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                                                                          769195-26-8
                                                                          Sitagliptin Phosphate
                                                                          SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma i...
                                                                          SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma intermediates, fine chemicals and pyridine derivatives for the domestic as well as international market. SS Pharma’s research activities extend from the development of active pharmaceuticals to fixed dose formulations for regulated markets. Its manufacturing facilities are state-of-the-art, multipurpose sites that comply with cGMP standards and meet the requirements of the US and EU drug regulatory authorities. SS Pharma is a CGMP, ISO 9001-2008 and ISO 14000:2004 certified company.
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                                                                          SS Pharma

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                                                                            (Z)Methyl 3-Acetomido-4-(2,4,5-Trifluorophenyl)But-2-En...

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                                                                            1234321-81-3
                                                                            Sitagliptin Phosphate
                                                                            SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma i...
                                                                            SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma intermediates, fine chemicals and pyridine derivatives for the domestic as well as international market. SS Pharma’s research activities extend from the development of active pharmaceuticals to fixed dose formulations for regulated markets. Its manufacturing facilities are state-of-the-art, multipurpose sites that comply with cGMP standards and meet the requirements of the US and EU drug regulatory authorities. SS Pharma is a CGMP, ISO 9001-2008 and ISO 14000:2004 certified company.
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                                                                            SS Pharma

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                                                                              Sitagliptin Enamine Impurity

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                                                                              767340-03-4
                                                                              Sitagliptin Phosphate
                                                                              SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma i...
                                                                              SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma intermediates, fine chemicals and pyridine derivatives for the domestic as well as international market. SS Pharma’s research activities extend from the development of active pharmaceuticals to fixed dose formulations for regulated markets. Its manufacturing facilities are state-of-the-art, multipurpose sites that comply with cGMP standards and meet the requirements of the US and EU drug regulatory authorities. SS Pharma is a CGMP, ISO 9001-2008 and ISO 14000:2004 certified company.
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                                                                              SS Pharma

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                                                                                (Z)-Methyl 3-Amino-4-(2,4,5-Trifluorophenyl)But-2-Enoat...

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                                                                                881995-70-6
                                                                                Sitagliptin Phosphate
                                                                                SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma i...
                                                                                SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma intermediates, fine chemicals and pyridine derivatives for the domestic as well as international market. SS Pharma’s research activities extend from the development of active pharmaceuticals to fixed dose formulations for regulated markets. Its manufacturing facilities are state-of-the-art, multipurpose sites that comply with cGMP standards and meet the requirements of the US and EU drug regulatory authorities. SS Pharma is a CGMP, ISO 9001-2008 and ISO 14000:2004 certified company.
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                                                                                SS Pharma

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                                                                                  Sitagliptin Impurity /Methyl®-3-Acetamido-4-(2,4,5-Tri...

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                                                                                  1234321-83-5
                                                                                  Sitagliptin Phosphate
                                                                                  SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma i...
                                                                                  SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma intermediates, fine chemicals and pyridine derivatives for the domestic as well as international market. SS Pharma’s research activities extend from the development of active pharmaceuticals to fixed dose formulations for regulated markets. Its manufacturing facilities are state-of-the-art, multipurpose sites that comply with cGMP standards and meet the requirements of the US and EU drug regulatory authorities. SS Pharma is a CGMP, ISO 9001-2008 and ISO 14000:2004 certified company.
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                                                                                  SS Pharma

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                                                                                    3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[...

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                                                                                    762240-92-6
                                                                                    Sitagliptin Phosphate
                                                                                    SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma i...
                                                                                    SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma intermediates, fine chemicals and pyridine derivatives for the domestic as well as international market. SS Pharma’s research activities extend from the development of active pharmaceuticals to fixed dose formulations for regulated markets. Its manufacturing facilities are state-of-the-art, multipurpose sites that comply with cGMP standards and meet the requirements of the US and EU drug regulatory authorities. SS Pharma is a CGMP, ISO 9001-2008 and ISO 14000:2004 certified company.
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                                                                                    Synaptics Labs

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                                                                                      3-trifluoromethyl 5,6,7,8 tetrahydro-[triazolo [4,3 a]-...

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                                                                                      762240-92-6
                                                                                      Sitagliptin Phosphate
                                                                                      Synaptics Labs Private Limited is a young Pharmaceutical Company with a fully integrated and globally spe...
                                                                                      Synaptics Labs Private Limited is a young Pharmaceutical Company with a fully integrated and globally specialized in the development, production and marketing of API’s "Active Pharmaceuticals Ingredients" and its advanced Intermediates, thanks to our focus on satisfying our customers' requirements and supporting the consolidation of a robust infrastructure. The Company promoted by a team of technocrats holding a master’s degree in pharmaceuticals and who have been involved in different Pharmaceutical companies since 24years.
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                                                                                      Synaptics Labs

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                                                                                        Boc-(-3-Amino 4-(2,4,5 trifluorophenyl)-butanoic acid

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                                                                                        486460-00-8
                                                                                        Sitagliptin Phosphate
                                                                                        Synaptics Labs Private Limited is a young Pharmaceutical Company with a fully integrated and globally spe...
                                                                                        Synaptics Labs Private Limited is a young Pharmaceutical Company with a fully integrated and globally specialized in the development, production and marketing of API’s "Active Pharmaceuticals Ingredients" and its advanced Intermediates, thanks to our focus on satisfying our customers' requirements and supporting the consolidation of a robust infrastructure. The Company promoted by a team of technocrats holding a master’s degree in pharmaceuticals and who have been involved in different Pharmaceutical companies since 24years.
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                                                                                        Vio Chemicals

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                                                                                          3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[...

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                                                                                          762240-92-6
                                                                                          Sitagliptin Phosphate
                                                                                          A Swiss chemical company specialized in custom design, development, production & sourcing of specialty ch...
                                                                                          A Swiss chemical company specialized in custom design, development, production & sourcing of specialty chemicals, intermediates and Active Pharmaceutical Ingredients. Driven by technological innovation and our passion for chemistry, we apply inspired science to create complete solutions for your business. With over 25 years of experience in highly regulated markets and a vast network of suppliers and manufacturing partners in Europe, Asia and the Americas, we are dedicated to excellence at every step, from the moment we conceive an idea to the moment we bring your product into the market. Excellence made in Switzerland, trusted by the world.
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                                                                                          veranova-m-2024-04-22

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                                                                                          Minakem offers CDMO services for API & HPAPI, generics, regulatory expertise, track record performance & FDA & GMP certifications.

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