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    CAS 183322-18-1

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    CAS 183322-18-1
    Also known as: 183322-18-1, Quinazoline, 4-chloro-6,7-bis(2-methoxyethoxy)-, Cp-335963, Mfcd09751265, K44upe46kj, 4-chloro-6,7-(2-methoxyethoxy)-quinazoline
    Molecular Formula
    C14H17ClN2O4
    Molecular Weight
    312.75  g/mol
    InChI Key
    ZPJLDMNVDPGZIU-UHFFFAOYSA-N
    FDA UNII
    K44UPE46KJ
    1 2D Structure

    CAS 183322-18-1

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-chloro-6,7-bis(2-methoxyethoxy)quinazoline
    2.1.2 InChI
    InChI=1S/C14H17ClN2O4/c1-18-3-5-20-12-7-10-11(16-9-17-14(10)15)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3
    2.1.3 InChI Key
    ZPJLDMNVDPGZIU-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    COCCOC1=C(C=C2C(=C1)C(=NC=N2)Cl)OCCOC
    2.2 Other Identifiers
    2.2.1 UNII
    K44UPE46KJ
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 183322-18-1

    2. Quinazoline, 4-chloro-6,7-bis(2-methoxyethoxy)-

    3. Cp-335963

    4. Mfcd09751265

    5. K44upe46kj

    6. 4-chloro-6,7-(2-methoxyethoxy)-quinazoline

    7. 4-chloro-6,7-bis-(2-methoxy-ethoxy)-quinazoline

    8. 4-chloro-6,7-bis-(2-methoxyethoxy)quinazoline

    9. Pf-508367

    10. 4-chloro-6,7-(2-methoxyethoxy)quinazoline

    11. Erlotinib Chloro Impurity

    12. Unii-k44upe46kj

    13. Di-n-octadecylphosphate

    14. Schembl163465

    15. Dtxsid70461407

    16. Hms3263i16

    17. Bcp26354

    18. Tox21_501087

    19. Zinc39326127

    20. Akos015851220

    21. Ac-6915

    22. Ccg-222391

    23. Cs-w007977

    24. Gs-4328

    25. Sb67325

    26. Ncgc00261772-01

    27. Sy017617

    28. Am20090620

    29. Ft-0650149

    30. 4-chloro-6,7-bis(2-methoxyethoxy) Quinazoline

    31. 4-chloro-6,7-di-(2-methoxyethoxy)quinazoline

    32. 4-chloro-6,7-bis (2-methoxyethoxy) Quinazoline

    33. 4-chloro-6,7-bis (2-methoxyethoxy)-quinazoline

    34. 4-chloro-6,7-bis-(2-methoxyethoxy)-quinazoline

    35. 4-chloro-6,7-di-(2-methoxyethoxy) Quinazoline

    36. Cp-335963, >=98% (hplc)

    37. (6,7-bis(2-methoxyethoxy))-4-chloro-quinazoline

    38. 322c181

    39. A812768

    40. Q-101338

    2.4 Create Date
    2006-10-26
    3 Chemical and Physical Properties
    Molecular Weight 312.75 g/mol
    Molecular Formula C14H17ClN2O4
    XLogP32.1
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count8
    Exact Mass312.0876847 g/mol
    Monoisotopic Mass312.0876847 g/mol
    Topological Polar Surface Area62.7 Ų
    Heavy Atom Count21
    Formal Charge0
    Complexity298
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
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                                    Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and ...
                                    Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and technical service of APIs, pharmaceutical intermediates and specialty chemicals. The marketing department is located in Nanjing. We have two GMP facilities in Jiangsu Province and cooperative factories in Zhejiang Province. The leading products range of the company is oncology and anti-diabetes . We also specialize in custom synthesis and contract research which demonstrates our state-of-the-art technology and capacity of synthesis.
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                                    Nanjing Lift Pharmaceutical Technol...

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                                      2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile

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                                      950596-58-4
                                      Erlotinib
                                      Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and ...
                                      Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and technical service of APIs, pharmaceutical intermediates and specialty chemicals. The marketing department is located in Nanjing. We have two GMP facilities in Jiangsu Province and cooperative factories in Zhejiang Province. The leading products range of the company is oncology and anti-diabetes . We also specialize in custom synthesis and contract research which demonstrates our state-of-the-art technology and capacity of synthesis.
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                                      Nanjing Lift Pharmaceutical Technol...

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                                        3-Aminophenylacetylene

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                                        54060-30-9
                                        Erlotinib
                                        Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and ...
                                        Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and technical service of APIs, pharmaceutical intermediates and specialty chemicals. The marketing department is located in Nanjing. We have two GMP facilities in Jiangsu Province and cooperative factories in Zhejiang Province. The leading products range of the company is oncology and anti-diabetes . We also specialize in custom synthesis and contract research which demonstrates our state-of-the-art technology and capacity of synthesis.
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                                        Nanjing Lift Pharmaceutical Technol...

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                                          N-(2-(Diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrr...

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                                          356068-86-5
                                          Erlotinib
                                          Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and ...
                                          Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and technical service of APIs, pharmaceutical intermediates and specialty chemicals. The marketing department is located in Nanjing. We have two GMP facilities in Jiangsu Province and cooperative factories in Zhejiang Province. The leading products range of the company is oncology and anti-diabetes . We also specialize in custom synthesis and contract research which demonstrates our state-of-the-art technology and capacity of synthesis.
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                                          Nantong Chem-land

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                                            6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone

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                                            179688-29-0
                                            Erlotinib
                                            Nantong Chem-land Co., Ltd. is located in Nantong city, a developed port city which distance from Shangha...
                                            Nantong Chem-land Co., Ltd. is located in Nantong city, a developed port city which distance from Shanghai is only 1.5 hours by car. Established in 2006, we have developed quickly into a comprehensive entity engaged in and marketing, developing and manufacturing of Active Pharmaceutical Ingredients, intermediates and fine chemicals.Our collaboration production site is in the national chemical park in our city: Nantong Rudong Yangkou Chemical park. Available test instrument in the production site: IR, UV, HPLC, GC, etc.. Production equipment: More than 50 reactors, size from 1L to 3000L , reaction temperature from -10℃ to +300℃.
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                                            Nantong Chem-land

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                                              4-Chloro-6,7-bis(2-methoxyethoxy)-4(3H)-quinazoline

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                                              183322-18-1
                                              Erlotinib
                                              Nantong Chem-land Co., Ltd. is located in Nantong city, a developed port city which distance from Shangha...
                                              Nantong Chem-land Co., Ltd. is located in Nantong city, a developed port city which distance from Shanghai is only 1.5 hours by car. Established in 2006, we have developed quickly into a comprehensive entity engaged in and marketing, developing and manufacturing of Active Pharmaceutical Ingredients, intermediates and fine chemicals.Our collaboration production site is in the national chemical park in our city: Nantong Rudong Yangkou Chemical park. Available test instrument in the production site: IR, UV, HPLC, GC, etc.. Production equipment: More than 50 reactors, size from 1L to 3000L , reaction temperature from -10℃ to +300℃.
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                                              Sagar Life Sciences

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                                                Trimethylsilyl Acetylene

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                                                1066-54-2
                                                Erlotinib
                                                We are a top producer of Pharmaceutical Intermediates, Specialty Chemicals, and More, with origins dating...
                                                We are a top producer of Pharmaceutical Intermediates, Specialty Chemicals, and More, with origins dating back to 1998. Globally renowned for its Organic Compounds, Inorganic Compounds, Industrial Acids, Industrial Chemicals, Zinc Acetates, Calcium Chloride Dihydrates, Speciality Chemicals, and other products, Sagar Life Science Private Limited is a customer-centric business with a primary focus on innovations, quality, and customization. Since sustainability is among our core values, we concentrate on improving the efficiency of our processes to manufacture sustainable results.
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                                                Sichuan Xieli Pharmaceutical

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                                                • EDQM
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                                                3-Aminophenylacetylene HCl

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                                                207226-02-6
                                                Erlotinib
                                                Xieli is an EU GMP\ Japan GMP\ Chinese GMP certified manufacturer of Botanical derivative APIs and Oncolo...
                                                Xieli is an EU GMP\ Japan GMP\ Chinese GMP certified manufacturer of Botanical derivative APIs and Oncology APIs from China.A leading producer of Rutin, Troxerutin, Diosmin, Artemisinin and Irinotecan HCL. DMF are available for products.Contract manufacturer for plant extraction, TCM, Solid formulation of Tablets, Granules, Capsules and etc with EU-GMP workshop.COS and cGMP application for products.R&D center, pilot scale plant, GMP workshops.
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                                                V & V Pharma Industries

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                                                  3,4-Dihydroxybenzaldehyde

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                                                  139-85-5
                                                  Erlotinib
                                                  V & V Pharma Industries is a Manufacturer & Exporter of Active Pharmaceutical Ingredients (API's), Pharma...
                                                  V & V Pharma Industries is a Manufacturer & Exporter of Active Pharmaceutical Ingredients (API's), Pharmaceutical Intermediates & Specialty Chemicals. V & V Pharma Industries is continuously engaged in the development of emerging technologies in collaboration with many Institutes & industrial centers of excellence. We have worked extensively and developed innovative technologies in the area of APIs intermediates Technology. Our innovative team of chemists has a proven track record in: process development, process optimization and scale-up.
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                                                  Zhejiang Apeloa Jiayuan Pharmaceuti...

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                                                  3,4-Dihydro-7-met hoxy-4-oxoquinaz olin-6-yl acetate

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                                                  179688-53-0
                                                  Erlotinib
                                                  Zhejiang Apeloa Medical Technology Co., Ltd.(Zhejiang Apeloa Jiayuan Pharmaceutical Co., Ltd.) is a medic...
                                                  Zhejiang Apeloa Medical Technology Co., Ltd.(Zhejiang Apeloa Jiayuan Pharmaceutical Co., Ltd.) is a medicinal industry enterprise integrating R&D, manufacturing，marketing and contract manufacture of Intermediates, API and Amino acid. She owns the GMP workshops and USA FDA site inspected the API division at May, 2007, intermediates division at Jan., 2009.R&D center is a State Certificate Enterprise and Postdoctoral Workstation. She has acquired USA FDA and SFDA approval and got GMP and certificates.
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                                                  polpharma-m-2024-04-15

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