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Details:
Zepbound (tirzepatide) injection acts by activating both, glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 hormone receptors. It is being evaluated for obstructive sleep apnea & obesity.
Lead Product(s): Tirzepatide
Therapeutic Area: Sleep Product Name: Zepbound
Highest Development Status: Phase IIIProduct Type: Peptide
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 17, 2024
Details:
Jardiance (empagliflozin) is an oral inhibitor of sodium-glucose co-transporter 2 (SGLT2) inhibitor, which is being evaluated for the treatment of myocardial infarction.
Lead Product(s): Empagliflozin
Therapeutic Area: Cardiology/Vascular Diseases Product Name: Jardiance
Highest Development Status: Phase IIIProduct Type: Small molecule
Recipient: Boehringer Ingelheim GmbH
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 06, 2024
Details:
Ebglyss (lebrikizumab) is an approved high-affinity and potent IL-13 inhibitor being studied in adult and adolescent patients 12 years of age and older with moderate-to-severe AD.
Lead Product(s): Lebrikizumab
Therapeutic Area: Dermatology Product Name: Ebglyss
Highest Development Status: ApprovedProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 10, 2024
Details:
LY3002813 (donanemab) is a humanized IgG1 monoclonal antibody targeted against an epitope at the N-terminal of a specific type of amyloid beta (Aβ) - which is found only in the brain amyloid plaques associated with Alzheimer's Disease (AD).
Lead Product(s): Donanemab
Therapeutic Area: Neurology Product Name: LY3002813
Highest Development Status: Phase IIIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 08, 2024
Details:
LY3002813 (donanemab) Is a humanized IgG1 monoclonal antibody targeted against an epitope at the N-terminal of a specific type of amyloid beta (Aβ) - which is found only in the brain amyloid plaques associated with Alzheimer's Disease (AD).
Lead Product(s): Donanemab
Therapeutic Area: Neurology Product Name: LY3002813
Highest Development Status: Phase IIIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 08, 2024
Details:
FHD-909 is a first-in-class oral BRM selective inhibitor. It is being evaluated in preclinical studies for the treatment of BRG1 mutated non-small cell lung cancer.
Lead Product(s): FHD-909
Therapeutic Area: Oncology Product Name: FHD-909
Highest Development Status: PreclinicalProduct Type: Small molecule
Recipient: Foghorn Therapeutics
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable February 08, 2024
Details:
Through the acquisition, Zuellig will have the access for Cialis (tadalafil), used to treat erectile dysfunction, and Alimta (pemetrexed), for the treatment of pleural mesothelioma and non-small cell lung cancer, from Eli Lilly.
Lead Product(s): Tadalafil
Therapeutic Area: Psychiatry/Psychology Product Name: Cialis
Highest Development Status: ApprovedProduct Type: Small molecule
Partner/Sponsor/Collaborator: Zuellig Pharma
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Acquisition February 06, 2024
Details:
IBI362 (mazdutide) is a GLP-1R and GCGR dual agonist. It is under phase 3 clinical development for the treatment of adults with overweight or obesity.
Lead Product(s): Mazdutide
Therapeutic Area: Nutrition and Weight Loss Product Name: IBI362
Highest Development Status: Phase IIIProduct Type: Peptide
Recipient: Innovent Biologics
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable January 08, 2024
Details:
IBI362 (mazdutide) is a glucagon-like peptide 1 receptor (GLP-1R) and glucagon receptor (GCGR) dual agonist, which is under phase 3 clinical development for the treatment of obesity.
Lead Product(s): Mazdutide
Therapeutic Area: Nutrition and Weight Loss Product Name: IBI362
Highest Development Status: Phase IIIProduct Type: Peptide
Recipient: Innovent Biologics
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable January 01, 2024
Details:
Through the acquisition, Lilly expands its oncology capabilities into next-generation radioligand therapies by including PNT2002 (177Lu-PNT2002), a PSMA targeted radioligand therapy in development for patients with metastatic castration-resistant prostate cancer.
Lead Product(s): 177Lu-PNT2002
Therapeutic Area: Oncology Product Name: PNT2002
Highest Development Status: Phase IIIProduct Type: Small molecule
Recipient: Point Biopharma
Deal Size: $1,400.0 million Upfront Cash: $1,400.0 million
Deal Type: Acquisition December 27, 2023