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    Find the latest Drugs in Development and Pipeline Prospector News of Chiltern International Ltd.

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    Chiltern International Ltd
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    Merus Presents Early Clinical Data on MCLA-158 and Preclinical Data on Zenocutuzumab at the AACR-NCI-EORTC Virtual International Conference on Molecular...

    Details:

    In preclinical models, MCLA-158 binding triggers EGFR degradation in LGR5+ CSCs and is designed to have two different mechanisms of action. The first entails blocking of growth and survival pathways in cancer initiating cells.


    Lead Product(s): Petosemtamab

    Therapeutic Area: Oncology Product Name: MCLA-158

    Highest Development Status: Phase IProduct Type: Large molecule

    Recipient: Merus

    Deal Size: Not Applicable Upfront Cash: Not Applicable

    Deal Type: Not Applicable October 07, 2021

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