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University of Oxford
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Country
United Kingdom
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Address
University Offices, Wellington Square, Oxford, OX1 2JD
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Telephone
+44 1865 270000

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The collaboration aims to evaluate the molecular MOA of EvolveImmune’s proprietary costimulatory T cell engager platform, EVOLVE, designed to unleash potent, selective, and integrated T cell costimulation to address unmet needs for the treatment of solid and hematologic tumor.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Discovery PlatformProduct Type: Cell and Gene therapy

Recipient: EvolveImmune Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration June 14, 2023

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Under the collaboration, University of Oxford and Selvita will advance potential therapeutics in the area of Parkinson's disease and have developed promising prototype compounds that efficiently promote the clearance of alpha-synuclein aggregates.


Lead Product(s): Undisclosed

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Undisclosed

Recipient: Selvita S.A

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration June 05, 2023

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Nigeria has granted provisional approval to Oxford University's R21 malaria vaccine which is composed of R21 Malaria antigen 5µg and Matrix-M1 50µg as an adjuvant.


Lead Product(s): R21 Malaria Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: R21

Highest Development Status: ApprovedProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 20, 2023

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The focus of the agreements is to apply the innovative technologies and research capabilities of the respective academic groups to identify, validate and prioritize key GPCRs driving gastrointestinal and immune disorders, including IBD, as targets for SBDD.


Lead Product(s): Undisclosed

Therapeutic Area: Gastroenterology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Undisclosed

Recipient: Sosei Heptares

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement December 08, 2022

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ChAdOx1 biEBOV provided as a liquid in glass vials and administered intramuscularly into the deltoid of the non-dominant arm. The vaccine will be administered intramuscularly (IM).


Lead Product(s): ChAdOx1 biEBOV

Therapeutic Area: Infections and Infectious Diseases Product Name: ChAdOx1 biEBOV

Highest Development Status: Phase IProduct Type: Vaccine

Recipient: Serum Institute of India

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 17, 2022

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The signing of amendment, as well as additional funding provided by BWV, will enable Oxford to continue research and optimization of the Company’s universal influenza vaccine candidate, BWV-101.


Lead Product(s): BWV-101

Therapeutic Area: Infections and Infectious Diseases Product Name: BWV-101

Highest Development Status: PreclinicalProduct Type: Vaccine

Recipient: Blue Water Vaccines

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement May 31, 2022

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The study achieved primary endpoint of reduction in nodule hardness at 12 months and secondary endpoint of reduction in nodule size at multiple time points including 12 months for anti-TNF injections adalimumab.


Lead Product(s): Adalimumab

Therapeutic Area: Dermatology Product Name: Humira

Highest Development Status: Phase IIProduct Type: Large molecule

Recipient: 180 Life Sciences

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 29, 2022

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Developing Elysium Health's proprietary algorithmic platform for epigenetic examination (APEX), and the company's biological age measure Index, Elysium Health plans to utilize the VITACOG biobank to explore the development and commercialization of novel brain health measures.


Lead Product(s): Micronutrient-based Dietary Supplement

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Small molecule

Recipient: Elysium Health

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership March 23, 2022

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Together with the University of Oxford, the Company plans to proceed with scaling up and Good Manufacturing Practice (GMP) production of HMGB1, as well as safety and toxicity testing in preparation for a planned Investigational New Drug (IND) application filing.


Lead Product(s): HMGB1

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: HMGB1

Highest Development Status: PreclinicalProduct Type: Peptide

Partner/Sponsor/Collaborator: 180 Life Sciences

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement December 15, 2021

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Com-COV3 study includes Novavax' recombinant nanoparticle COVID-19 vaccine candidate, NVX-CoV2373, is one of the three COVID-19 vaccines that combined regimens that mix vaccines from different manufacturers to achieve immune protection against COVID-19.


Lead Product(s): NVX-CoV2373,Matrix-M1

Therapeutic Area: Infections and Infectious Diseases Product Name: Covovax

Highest Development Status: Phase IIIProduct Type: Vaccine

Recipient: Novavax

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 16, 2021

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