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    Pharma Services Category of PharmaVize NV

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    HTL Biotechnology is the world leader in the responsible development and production of pharmaceutical-grade biopolymers.
    Polpharma is a Polish CDMO of APIs and a significant European API producer, delivering products to companies worldwide.
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    01 API Development (2)

    02 Analytical Method Development (1)

    03 Analytical Testing Services (4)

    04 Formulation Development (19)

    05 Preformulation & Material Science (6)

    06 Stability Studies (1)

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    01 PharmaVize NV (33)

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    01 Belgium (33)

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    PharmaVize NV

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      SOLUBILITY SCREENING

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      PharmaVize offers solubility screening and bioavailability enhancement to accelerate your drug development and approval processes.

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      Pharma Service: API & Drug Product Development

      Category: Preformulation & Material Science

      Sub Category: Solubility Assessment & Enhancement
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        PREFORMULATION CONCEPT STUDIES

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        Preformulation concept studies to accelerate your drug development and approval.

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        Pharma Service: API & Drug Product Development

        Category: Preformulation & Material Science

        Sub Category: Overview
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          EARLY PHASE FORMULATION DEVELOPMENT

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          Early phase formulation development to accelerate your drug development and approval.

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          Pharma Service: API & Drug Product Development

          Category: Preformulation & Material Science

          Sub Category: Overview
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            DEVELOPMENT OF DRUG DELIVERY SYSTEMS FOR CONTROLLED OR ...

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            Development of drug delivery systems for controlled or in situ release to accelerate your drug development and approval.

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            Pharma Service: API & Drug Product Development

            Category: Formulation Development

            Sub Category: Overview
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              FORMULATION OPTIMIZATION OF MARKETED OR EXISTING DRUGS

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              Formulation optimization of marketed or existing drugs to accelerate your drug development and approval.

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              Pharma Service: API & Drug Product Development

              Category: Formulation Development

              Sub Category: Overview
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                PROCESS FEASIBILITY TESTING & UPSCALING

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                Process feasibility testing & upscaling to accelerate your drug development and approval.

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                Pharma Service: API & Drug Product Development

                Category: Formulation Development

                Sub Category: Overview
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                  PROCESS VALIDATION

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                  Process validation to accelerate your drug development and approval.

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                  Pharma Service: API & Drug Product Development

                  Category: Formulation Development

                  Sub Category: Overview
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                    SOLUTIONS AND (NANO-)SUSPENSIONS

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                    Pharmavize can manufacture various dosage forms including solutions and (nano-)suspensions.

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                    Pharma Service: API & Drug Product Development

                    Category: Formulation Development

                    Sub Category: Liquid Formulation
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                      POWDER AND GRANULE FILLED CAPSULES

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                      Pharmavize can manufacture various dosage forms including powder and granule filled capsules.

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                      Pharma Service: API & Drug Product Development

                      Category: Formulation Development

                      Sub Category: Capsule
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                        SEMI-SOLID AND LIQUID FILLED CAPSULES

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                        Pharmavize can manufacture various dosage forms including semi-solid and liquid filled capsules.

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                        Pharma Service: API & Drug Product Development

                        Category: Formulation Development

                        Sub Category: Capsule
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                          TOPICAL PRODUCTS

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                          Pharmavize can manufacture various dosage forms including topical products

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                          Pharma Service: API & Drug Product Development

                          Category: Formulation Development

                          Sub Category: Cream / Gel / Lotion / Ointment
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                            DEVELOPMENT & MANUFACTURING OF TABLETS

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                            Pharmavize can manufacture various dosage forms including oral solid forms like tablets.

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                            Pharma Service: API & Drug Product Development

                            Category: Formulation Development

                            Sub Category: Tablet
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                              MODIFIED-RELEASE FORMULATIONS

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                              Pharmavize can manufacture various oral dosage forms including CDMO modified release tablets.

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                              Pharma Service: API & Drug Product Development

                              Category: Formulation Development

                              Sub Category: Controlled / Immediate / Modified Release
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                                PELLETS AND MICROSPHERES

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                                Pharmavize can manufacture various dosage forms including pellets and microspheres.

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                                Pharma Service: API & Drug Product Development

                                Category: Formulation Development

                                Sub Category: Liposome / Microsphere / Nanoparticle
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                                  SPRAY-DRIED POWDERS

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                                  Pharmavize can manufacture various dosage forms including spray-dried powders.

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                                  Pharma Service: API & Drug Product Development

                                  Category: Formulation Development

                                  Sub Category: Powder / Blend
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                                    POWDER BLENDS FOR RECONSTITUTION

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                                    Pharmavize can manufacture various dosage forms including powder blends for reconstitution.

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                                    Category: Formulation Development

                                    Sub Category: Powder / Blend
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                                      OVER ENCAPSULATED PRODUCTS

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                                      Pharmavize can manufacture various dosage forms including overencapsulated products.

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                                      Pharma Service: API & Drug Product Development

                                      Category: Formulation Development

                                      Sub Category: Capsule
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                                        SMALL SCALE MANUFACTURING SERVICES

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                                        No batch is too small for PharmaVize NV. Small-scale manufacturing is what they do best.

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                                        Pharma Service: API & Drug Product Development

                                        Category: Formulation Development

                                        Sub Category: Scale-Up Capabilities
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                                          PRECLINICAL BATCHES/ NON-GMP PILOT BATCHES

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                                          No batch is too small for PharmaVize NV. Small-scale manufacturing is what they do best.

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                                          Pharma Service: API & Drug Product Development

                                          Category: Formulation Development

                                          Sub Category: Scale-Up Capabilities
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                                            CLINICAL SUPPLY MANAGEMENT

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                                            A full service CDMO able to meet your clinical trial material & supply needs. PharmaVize specializes in developing clinical supply materials and providing clinical supplies management from design to delivery within a given time frame.

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                                            Pharma Service: API & Drug Product Development

                                            Category: Formulation Development

                                            Sub Category: Clinical Supply
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                                              MOISTURE OR OXYGEN SUSCEPTIBLE APIs

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                                              The use of lipid formulations may help you to overcome aqueous solubility problems. This technology may also be used for APIs exhibiting moisture or oxygen related stability issues.

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                                              Pharma Service: API & Drug Product Development

                                              Category: Formulation Development

                                              Sub Category: Lipid Formulation
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                                                NANONIZATION OF APIs

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                                                Pharmavize is using dry and wet milling techniques to reduce the particle size or your drug candidate. Nanonization will increase the surface-to-volume ratio of APIs which may result in a better API solubilization and hence increasing drug bio-availabilit

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                                                Category: Formulation Development

                                                Sub Category: Liposome / Microsphere / Nanoparticle
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                                                  SPRAY DRYING OF APIs

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                                                  When using spray drying, your API can be co-precipitated with a polymer into a stable amorphous solid dispersion. Spray drying is an elegant technique to engineer powder characteristics such as particle size, density and flowability.

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                                                  Category: API Development

                                                  Sub Category: Spray Drying
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                                                    SOLID FORM SCREEN: SALT SCREENING

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                                                    Crystallics' technology platform accommodates salt screening studies using only minimal amounts of drug substance while still performing a large number of experiments. High-throughput salt screening is used for both early phase salt selection studies and

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                                                    Pharma Service: API & Drug Product Development

                                                    Category: Preformulation & Material Science

                                                    Sub Category: Salt Screening
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                                                      SOLID FORM SCREENING: POLYMORPH & CRYSTAL SCREENING

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                                                      Crystallics’ unique polymorph screening methodology enhances understanding of the polymorphic behavior of drug candidates.

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                                                      Pharma Service: API & Drug Product Development

                                                      Category: Preformulation & Material Science

                                                      Sub Category: Polymorph & Crystal Screening
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                                                        CRYSTALLIZATION PROCESS SUPPORT

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                                                        Crystallics has the right systems and equipment to help its customers understand and control crystallization processes and thus gain insight into how to improve yield, control particle size and habit, and reduce process time.

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                                                        Pharma Service: API & Drug Product Development

                                                        Category: API Development

                                                        Sub Category: Crystallization Process
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                                                          POWDER PROPERTIES

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                                                          Crystallics has capabilities to determine powder properties like bulk and tap density, flow properties, odor & color, electrostatics, compression properties, compaction properties, milling, grinding & granulation (chemical physical stability).

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                                                          Pharma Service: API & Drug Product Development

                                                          Category: Preformulation & Material Science

                                                          Sub Category: Overview
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                                                            API CHARACTERIZATION

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                                                            Pharmavize operates an audited 1,600-m2 GMP facility serving clients from all over the world. We are thoroughly familiar with the European and American regulatory frameworks and guarantee compliance with all applicable guidelines and directives.

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                                                            Pharma Service: Analytical

                                                            Category: Analytical Testing Services

                                                            Sub Category: Physical Characterization
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                                                              IDENTIFICATION OF DEGRADANT PRODUCTS & IMPURITIES (LC/M...

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                                                              Pharmavize operates an audited 1,600-m2 GMP facility serving clients from all over the world. We are thoroughly familiar with the European and American regulatory frameworks and guarantee compliance with all applicable guidelines and directives.

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                                                              Pharma Service: Analytical

                                                              Category: Analytical Testing Services

                                                              Sub Category: Mass Spectrometry and LC / MS
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                                                                HPLC/UPLC/GC METHOD DEVELOPMENT & OPTIMIZATION

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                                                                Pharmavize operates an audited 1,600-m2 GMP facility serving clients from all over the world. We are thoroughly familiar with the European and American regulatory frameworks and guarantee compliance with all applicable guidelines and directives.

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                                                                Pharma Service: Analytical

                                                                Category: Analytical Testing Services

                                                                Sub Category: Chromatography (TLC / LC / HPLC / UPLC / GC)
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                                                                  DISSOLUTION METHOD DEVELOPMENT

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                                                                  Pharmavize operates an audited 1,600-m2 GMP facility serving clients from all over the world. We are thoroughly familiar with the European and American regulatory frameworks and guarantee compliance with all applicable guidelines and directives.

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                                                                  Pharma Service: Analytical

                                                                  Category: Analytical Testing Services

                                                                  Sub Category: Dissolution
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                                                                    METHOD VALIDATION & TRANSFER ACTIVITIES

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                                                                    Pharmavize operates an audited 1,600-m2 GMP facility serving clients from all over the world. We are thoroughly familiar with the European and American regulatory frameworks and guarantee compliance with all applicable guidelines and directives.

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                                                                    Pharma Service: Analytical

                                                                    Category: Analytical Method Development

                                                                    Sub Category: Method Development and Validation
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                                                                      ICH COMPLIANT STABILITY PROGRAMS

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                                                                      Our ICH stability storage facilities consist of over 100 m3 of walk-in stability rooms, fully secured with 24/7 electronic monitoring, alarm and backup power.

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                                                                      Pharma Service: Analytical

                                                                      Category: Stability Studies

                                                                      Sub Category: Overview
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