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    Pharma Services Category of Farmhispania, S.A

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    HTL Biotechnology is the world leader in the responsible development and production of pharmaceutical-grade biopolymers.
    Polpharma is a Polish CDMO of APIs and a significant European API producer, delivering products to companies worldwide.
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    01 Analytical Method Development (1)

    02 Biologics, Bioprocess & Fermentation (1)

    03 Clinical Supply (2)

    04 Continuous Flow Process (2)

    05 Cytotoxic Compound (1)

    06 Drying (1)

    07 Fine Chemical / Intermediate (1)

    08 GMP Manufacturing (1)

    09 High Potency APIs (HPAPIs) (3)

    10 Hydrogenation (1)

    11 Low Temperature / Cryogenic conditions (1)

    12 Lyophilization (1)

    13 Process Development & Optimization (1)

    14 Scale Up (1)

    15 Separation & Purification (3)

    16 Small Scale Batch (1)

    17 Stability Studies (1)

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    01 Farmhispania (23)

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    01 Spain (23)

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    Farmhispania

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    PILOT PLANTS & KILO-LABS

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    Farmhispania Group has at both sites pilot plants and kilo-labs to scale up manufacturing processes and carry out cGMP manufacture of API´s for Clinical Trials and commercial supply.

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    Pharma Service: API Manufacturing

    Category: Small Scale Batch

    Sub Category: Overview
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    SCALE UP

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    Farmhispania Group has at both sites pilot plants and kilo-labs to scale up manufacturing processes and carry out cGMP manufacture of API´s for Clinical Trials and commercial supply.

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    Pharma Service: API Manufacturing

    Category: Scale Up

    Sub Category: Overview
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    cGMP MANUFACTURE OF API

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    Farmhispania Group has at both sites pilot plants and kilo-labs to scale up manufacturing processes and carry out cGMP manufacture of API´s for Clinical Trials and commercial supply.

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    Pharma Service: API Manufacturing

    Category: GMP Manufacturing

    Sub Category: Overview
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    cGMP MANUFACTURE OF API FOR CLINICAL TRIALS

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    Farmhispania Group has pilot plants and kilo-labs to scale up manufacturing processes and carry out cGMP manufacture of APIs for clinical trials and commercial supply.

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    Pharma Service: API Manufacturing

    Category: Clinical Supply

    Sub Category: Overview
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    TEMPERATURE RANGE FROM -70 TO 200 ºC

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    Farmhispania Groups equipment includes: vessels from 5 to 1000 L, temperature range from -70 to 200 ºC, filtration equipment, centrifuges and a wide range of handling equipment to mill, dry and lyophilise the bulk product.

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    Pharma Service: API Manufacturing

    Category: Low Temperature / Cryogenic conditions

    Sub Category: Overview
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    FILTRATION EQUIPMENT

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    Farmhispania Groups equipment includes: vessels from 5 to 1000 L, temperature range from -70 to 200 ºC, filtration equipment, centrifuges and a wide range of handling equipment to mill, dry and lyophilise the bulk product.

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    Pharma Service: API Manufacturing

    Category: Separation & Purification

    Sub Category: Extraction & Isolation
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    CENTRIFUGES

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    Farmhispania Groups equipment includes: vessels from 5 to 1000 L, temperature range from -70 to 200 ºC, filtration equipment, centrifuges and a wide range of handling equipment to mill, dry and lyophilise the bulk product.

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    Pharma Service: API Manufacturing

    Category: Separation & Purification

    Sub Category: Extraction & Isolation
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    DRYING OF THE BULK PHARMACEUTICAL PRODUCTS

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    Farmhispania Groups equipment includes: vessels from 5 to 1000 L, temperature range from -70 to 200 ºC, filtration equipment, centrifuges and a wide range of handling equipment to mill, dry and lyophilise the bulk product.

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    Pharma Service: API Manufacturing

    Category: Drying

    Sub Category: Overview
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    LYOPHILIZATION OF THE BULK PRODUCT

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    Farmhispania Groups equipment includes: vessels from 5 to 1000 L, temperature range from -70 to 200 ºC, filtration equipment, centrifuges and a wide range of handling equipment to mill, dry and lyophilise the bulk product.

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    Pharma Service: API Manufacturing

    Category: Lyophilization

    Sub Category: Overview
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    HPAPI

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    HPAPI, Farmhispania Group has recently opened a kilo-HPAPI area where we have two lines with vessels from 10 to 63 L, including Aurora filter and a tray drier.

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    Pharma Service: API Manufacturing

    Category: High Potency APIs (HPAPIs)

    Sub Category: Overview
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    KILO-HPAPI

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    For HPAPI, Farmhispania Group has recently opened a kilo-HPAPI area where we have two lines with vessels from 10 to 63 L, including Aurora filter and a tray drier.

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    Pharma Service: API Manufacturing

    Category: High Potency APIs (HPAPIs)

    Sub Category: Overview
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    ADVANCED INTERMEDIATES

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    Farmhispania Group develops and manufactures a diverse range of API’s, advanced intermediates and building blocks. Furthermore, Farmhispania Group provides PR&D and manufacturing services to support clinical trials and commercial supply.

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    Pharma Service: API Manufacturing

    Category: Fine Chemical / Intermediate

    Sub Category: Overview
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    CDMO FOR CLINICAL & COMMERCIAL SUPPLY OF APIs

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    Farmhispania is involved in the contract development & manufacturing of a diverse range of APIs, advanced intermediates & building blocks. Furthermore, they provide PR&D and manufacturing services to support clinical & commercial supply.

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    Pharma Service: API Manufacturing

    Category: Biologics, Bioprocess & Fermentation

    Sub Category: Overview
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    HYDROGENATION

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    Farmhispania Group develops and manufactures a diverse range of API’s, advanced intermediates and building blocks. Furthermore, Farmhispania Group provides PR&D and manufacturing services to support clinical trials and commercial supply.

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    Pharma Service: API Manufacturing

    Category: Hydrogenation

    Sub Category: Overview
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    FLOW CHEMISTRY

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    Farmhispania Group develops and manufactures a diverse range of API’s, advanced intermediates and building blocks. Furthermore, Farmhispania Group provides PR&D and manufacturing services to support clinical trials and commercial supply.

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    Pharma Service: API Manufacturing

    Category: Continuous Flow Process

    Sub Category: Overview
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    CYTOTOXICS MANUFACTURING

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    The HPAPI Technical Centre, located at the Montmeló site, has different facilities to develop, scale up and cGMP manufacture highly potent API including cytotoxics with an OEL below 30 ng/m3, from a few small grams to multi kilograms.

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    Pharma Service: API Manufacturing

    Category: Cytotoxic Compound

    Sub Category: Overview
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    HIGHLY POTENT FERMENTATION CAPABILITIES

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    Farmhispania's Zaragoza site includes complete equipment to the upstream and downstream parts of the fermentation process, from small scale to large scale production. Currently we are carrying out aerobic fermentation of complex potent products.

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    Pharma Service: API Manufacturing

    Category: High Potency APIs (HPAPIs)

    Sub Category: Overview
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    FLOW CHEMISTRY

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    Continuous-flow technology involves the continuous introduction of a stream of chemical reactants into a tube reactor or a microreactor to yield a desired reaction product on a continuous basis.

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    Pharma Service: API Manufacturing

    Category: Continuous Flow Process

    Sub Category: Overview
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    PURIFICATION OF PRODUCTS VIA HPLC

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    Farmhispania Group has large scale preparative HPLC systems to permit the purification of products using different detectors as a fraction trigger and valve configurations to accommodate virtually any number of single or multiple column schemes.

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    Pharma Service: API Manufacturing

    Category: Separation & Purification

    Sub Category: Extraction & Isolation
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    CLINICAL PHASE 1 & 2A cGMP MANUFACTURING

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    Farmhispania Group offers custom process development and custom manufacturing services for APIs, advanced intermediates and building blocks for pharmaceutical, biopharmaceutical and related industries.

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    Pharma Service: API Manufacturing

    Category: Clinical Supply

    Sub Category: Overview
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    ANALYTICAL METHOD VALIDATION / VERIFICATION

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    Farmhispania Group offers custom process development and custom manufacturing services for API’s, advanced intermediates and building blocks for the pharmaceutical, biopharmaceutical and related industries.

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    Pharma Service: Analytical

    Category: Analytical Method Development

    Sub Category: Method Development and Validation
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    PROCESS VALIDATION

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    Farmhispania Group offers custom process development and custom manufacturing services for API’s, advanced intermediates and building blocks for the pharmaceutical, biopharmaceutical and related industries.

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    Pharma Service: API Manufacturing

    Category: Process Development & Optimization

    Sub Category: Overview
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    STABILITY STUDIES

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    Farmhispania Group offers custom process development and custom manufacturing services for API’s, advanced intermediates and building blocks for the pharmaceutical, biopharmaceutical and related industries.

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    Pharma Service: Analytical

    Category: Stability Studies

    Sub Category: Overview
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