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Looking for Tox21_300144? Find Tox21_300144 based excipient solutions to address drug delivery challenges on PharmaCompass.

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Applications:

Sorbiplast (Sorbitol) is used as a plasticizer that provides the required elasticity in soft-gelatin capsules.

Ingredient(s): Sorbitol

Dosage Form: Softgels

Category: Film Formers & Plasticizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: USP-NF, IH

Technical Specifications: NA

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Applications:

KoVidone® K25 is used as a low viscosity wet binder.

Ingredient(s): Polyvinylpyrrolidone

Dosage Form: Capsule, Tablet

Category: Fillers, Diluents & Binders

Route of Administration (Grade): Oral
Pharmacopoeia Reference: USP/NF, EP, JP, KP, IP, BP

Technical Specifications: NA

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Applications:

Sucralose is used as taste masking excipient in various formulations such as tablet, capsule, suspension & liquid, etc.

Ingredient(s): Sucralose

Dosage Form: Capsule, Liquid, Suspension, Syrup, Tablet

Category: Taste Masking

Route of Administration (Grade): Oral
Pharmacopoeia Reference: NA

Technical Specifications: NA

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Applications:

Castor oil is used as an oily solvent in parenteral dosage forms.

Ingredient(s): Castor Oil Excipient

Dosage Form: Injectable / Parenteral

Category: Parenteral

Route of Administration (Grade): Parenteral
Pharmacopoeia Reference: USP/EP/JP

Technical Specifications: NA

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Applications:

It stabilizes the pH of solutions. It is also an enzyme inhibitor used in the biopharmaceutical industry.

Ingredient(s): Tromethamine

Dosage Form: Cream / Lotion / Ointment, Injectable / Parenteral

Category: Parenteral, Topical

Route of Administration (Grade): Topical, Parenteral
Pharmacopoeia Reference: Not Available

Technical Specifications: Bio Excipient Grade

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Ingredient(s): Hydroxypropyl Methylcellulose

Dosage Form: Tablet

Category: Coating Systems & Additives

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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BENZYL ALCOHOL MULTI-COMPENDIAL

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Applications:

A&C’s Benzyl Alcohol multi-compendial is a preservative which meets USP-NF, EP, BP and JP monographs.

Ingredient(s): Benzyl Alcohol Excipient

Dosage Form: Cream / Lotion / Ointment

Category: Topical

Route of Administration (Grade): Oral, Parenteral
Pharmacopoeia Reference: Multi-compendial

Technical Specifications: Not Available

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Applications:

Tablet film coating, binders , main material of plant capsules.

Ingredient(s): Hypromellose

Dosage Form: Capsule, Tablet

Category: Fillers, Diluents & Binders, Film Formers & Plasticizers

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: USP/BP/EP/CP

Technical Specifications: Not Available

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ACECEL

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Applications:

AceCel is suitable for majority of the directly compressible actives, combines good flow and high compressibility.

Ingredient(s): Microcrystalline Cellulose

Dosage Form: Tablet

Category: Direct Compression, Fillers, Diluents & Binders, Granulation

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications:

It is used as a suspending agent.

Ingredient(s): Carbomer Excipient

Dosage Form: Capsule, Tablet

Category: Solubilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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L-RHAMNOSE MONOHYDRATE

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Applications:

HEGENG Brand High Purity L-Rhamnose is available in the field of biotechnology including plant cytology, microbial technology, genetic engineering, fermentation technology and immunology.

Ingredient(s): L Rhamnose Excipient

Dosage Form: Cream / Lotion / Ointment, Gel

Category: Topical

Route of Administration (Grade): Topical
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications:

For non-erodible matrices using direct compression, Controlled release matrix. Matrix former in transdermal patches and topical films.

Ingredient(s): Hydrated Silica, Lauryl Sulfate, Polyvinyl Acetate, Povidone

Dosage Form: Capsule, Tablet, Topical Film, Transdermal Patch

Category: Controlled & Modified Release, Direct Compression, Granulation

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: Ph. Eur., USP-NF, JP-JPE: 80 % Polyvinyl acetate and 19 % povidone, 0.8 % lauryl sulfate & 0.2 % silica (4:1)

Technical Specifications: Not Available

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Applications:

Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

Ingredient(s): Microcrystalline Cellulose

Dosage Form: Tablet

Category: Direct Compression

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Conforms to USP-NF, Ph.Eur., JP, IP

Technical Specifications: Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

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Applications:

It is used as solubilizers for paclitaxel, cyclosporine, vitamin K1.

Ingredient(s): Polyoxyl 35 Castor Oil

Dosage Form: Tablet, Injectable / Parenteral

Category: API Stability Enhancers, Solubilizers

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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TALC

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Applications:

Talc is a widely used as a dissolution retardant in the development of controlled release products. Talc is also used as a lubricant in tablet formulations.

Ingredient(s): Talc Excipient

Dosage Form: Granule / Pellet, Tablet

Category: Controlled & Modified Release, Lubricants & Glidants

Route of Administration (Grade): Oral & Topical
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications:

A&C’s Benzalkonium Chloride 17% is a preservative which meets the NF monograph.

Ingredient(s): Benzalkonium chloride excipient

Dosage Form: Injectable / Parenteral, Tablet

Category: Solubilizers

Route of Administration (Grade): Oral, Parenteral
Pharmacopoeia Reference: USP NF

Technical Specifications: 17% USP NF

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Applications:

Polyglykol 1500 S is a flaked PEG excipient grade product which is used as humectant, solvent and ointment base in the topical formulations.

Ingredient(s): Polyethylene Glycol 1500

Dosage Form: Cream / Lotion / Ointment

Category: Topical

Route of Administration (Grade): Topical
Pharmacopoeia Reference: USP-NF: Polyethylene glycol 1500, Ph. Eur.: Macrogol 1500

Technical Specifications: average molar mass 1500 g/mol

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Applications:

It is used in producing the injection solution, reducing the encephalic pressure, the intraocular pressure etc.

Ingredient(s): Mannitol

Dosage Form: Injectable / Parenteral, Tablet

Category: Fillers, Diluents & Binders, Parenteral

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: CP/BP/ EP/ USP/IP

Technical Specifications: Pharma Grade/ Medicine Grade/Injectable Grade

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PROPYLENE GLYCOL

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Ingredient(s): Propylene Glycol

Dosage Form: Capsule, Cream / Lotion / Ointment

Category: Film Formers & Plasticizers, Topical

Route of Administration (Grade): Topical and Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications:

Solubilizer, Dissolution Improver, Emulsifier, Masking Agent, Moisturizer, Aerosol Formulations

Ingredient(s): Polyoxyl 35 Hydrogenated Castor Oil

Dosage Form: Emulsion, Injectable / Parenteral, Solution, Suspension

Category: Emulsifying Agents, Parenteral, Solubilizers

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications:

Adsorbent, Moisture Protection, Stabilization of API

Ingredient(s): Silicon Dioxide

Dosage Form: Tablet

Category: API Stability Enhancers, Thickeners and Stabilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: USP-NF, JP, EP

Technical Specifications: Also Available as FUJISIL-F

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Applications:

Nonionic solubilizer, emulsifier and co-emulsifier

Ingredient(s): Polysorbate 20

Dosage Form: Gel, Softgel Capsule, Solution, Suppository

Category: Solubilizers

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: Ph. Eur., USP-NF

Technical Specifications: Not Available

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HICEL

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Applications:

HiCel acts as a strong & dry binder. It facilitates low tablet friability & promotes rapid tablet disintegration.

Ingredient(s): Microcrystalline Cellulose

Dosage Form: Tablet

Category: Direct Compression, Fillers, Diluents & Binders, Granulation

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications:

It is used as a filler in formulation.

Ingredient(s): Microcrystalline Cellulose

Dosage Form: Capsule, Tablet

Category: Fillers, Diluents & Binders

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Also Available as Comprecel M102, M102CG, M103, M105, M124, M113, M200, M224, M301, M302

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KAOLIN

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Applications:

Kaolin is a naturally occurring mineral used in oral and topical pharmaceutical formulations

Ingredient(s): Kaolin Excipient

Dosage Form: Cream / Lotion / Ointment, Tablet, Transdermal Patch

Category: Controlled & Modified Release, Topical

Route of Administration (Grade): Topical & Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications:

Sustained Release Tablet Matrix

Ingredient(s): Hydroxypropyl Methylcellulose

Dosage Form: Capsule, Tablet

Category: Coating Systems & Additives, Controlled & Modified Release

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: USP, EP, and JP

Technical Specifications: Not Available

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UREA

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Ingredient(s): Urea

Dosage Form: Cream / Lotion / Ointment

Category: Topical

Route of Administration (Grade): Topical
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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BENZALKONIUM CHLORIDE

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Ingredient(s): Benzalkonium chloride excipient

Dosage Form: Nasal Solution, Ophthalmic Solution

Category: Parenteral

Route of Administration (Grade): Ophthalmic and Nasal
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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CALCIUM CHLORIDE DIHYDRATE MULTI-COMPENDIAL

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Applications:

A & C's Calcium Chloride Dihydrate multi-compendial is an excipient, which meets USP-NF, EP and BP monographs.

Ingredient(s): CALCIUM CHLORIDE DIHYDRATE Excipient

Dosage Form: Tablet

Category: Fillers, Diluents & Binders

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Multi-compendial

Technical Specifications: Not Available

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Applications:

Polysorbate 80 acts as solubilizer, emulsifier and wetting agent.

Ingredient(s): Polysorbate 80

Dosage Form: Capsule, Cream / Lotion / Ointment, Suspension, Tablet

Category: Solubilizers, Surfactant & Foaming Agents

Route of Administration (Grade): Oral, Topical & Parenteral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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2-PHENOXYETHANOL PHEUR

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Applications:

A & C's 2-Phenoxyethanol is used as an excipient and meets the EP monograph

Ingredient(s): 2-Phenoxyethanol Excipient

Dosage Form: Cream / Lotion / Ointment

Category: Topical

Route of Administration (Grade): Topical
Pharmacopoeia Reference: PhEur

Technical Specifications: Not Available

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Applications:

Solubilizing agents and Stabilizers.

Ingredient(s): Beta-Cyclodextrin

Dosage Form: Tablet

Category: Solubilizers, Thickeners and Stabilizers

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: USP/BP/EP/CP

Technical Specifications: Not Available

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Applications:

It is used as a filler in formulation.

Ingredient(s): Mannitol

Dosage Form: Capsule, Tablet

Category: Fillers, Diluents & Binders

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications:

Polyglykol 400 is a liquid PEG excipient grade product which is used as solvent, humectant, coating agent and viscosity enhancer.

Ingredient(s): Polyethylene Glycol 400

Dosage Form: Cream / Lotion / Ointment, Emulsion

Category: Coating Systems & Additives, Rheology Modifiers, Topical

Route of Administration (Grade): Topical
Pharmacopoeia Reference: USP-NF: Polyethylene glycol 400, J.P.: Macrogol 400, Ph. Eur.: Macrogol 400

Technical Specifications: average molar mass 400 g/mol

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POLYETHYLENE GLYCOL 400 NF

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Ingredient(s): polyethylene glycol

Dosage Form: Capsule, Cream / Lotion / Ointment, Gel, Tablet

Category: Controlled & Modified Release, Topical

Route of Administration (Grade): Topical and Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications:

Pharmacel® 101 is a pharmaceutical excipient that acts as a pharmaceutical binder & filler for wet and dry granulation as it ensures uniform granulation and drying processes. It also provides excellent compaction and disintegration.

Ingredient(s): Microcrystalline Cellulose

Dosage Form: Tablet

Category: Fillers, Diluents & Binders

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Conforms to USP-NF, Ph.Eur., JP, IP

Technical Specifications: Density- Tapped density- 440 g/l, Bulk density- 280 g/l; Particle size- D10- 25 ?m, D50- 60 ?m, D90- 20 ?m; Hausner ratio-1,57

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Applications:

Nonionic solubilizer, emulsifier and co-emulsifier

Ingredient(s): Polysorbate 60

Dosage Form: Gel, Softgel Capsule, Solution, Suppository

Category: Solubilizers

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: Ph. Eur., USP-NF

Technical Specifications: Not Available

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Applications:

Standard Direct Tabletting

Ingredient(s): Glyceryl Monostearate, Mannitol

Dosage Form: Tablet

Category: Co-Processed Excipients

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: NF/EP/JP

Technical Specifications: Not Available

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Applications:

Instamodel Blend is used to provide Extended Release from the dosage form.

Ingredient(s): HPMC 2910

Dosage Form: Tablet

Category: Controlled & Modified Release

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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BENTONITE

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Applications:

Bentonite is used in topical & oral preparations, formulation of suspensions and gels, aqueous preparation, cream bases and antidote in heavy metal poisoning.

Ingredient(s): Bentonite Excipient

Dosage Form: Cream / Lotion / Ointment, Gel, Suspension

Category: Rheology Modifiers, Topical

Route of Administration (Grade): Oral and Topical
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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