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Chemistry

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Also known as: 29560-58-5, Moracizine hydrochloride, Ethmozine, Ethmosine, Moricizine hcl, Moricizine (hydrochloride)
Molecular Formula
C22H26ClN3O4S
Molecular Weight
464.0  g/mol
InChI Key
GAQAKFHSULJNAK-UHFFFAOYSA-N
FDA UNII
71OK3Z1ESP

Moricizine
An antiarrhythmia agent used primarily for ventricular rhythm disturbances.
1 2D Structure

Moricizine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
ethyl N-[10-(3-morpholin-4-ylpropanoyl)phenothiazin-2-yl]carbamate;hydrochloride
2.1.2 InChI
InChI=1S/C22H25N3O4S.ClH/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24;/h3-8,15H,2,9-14H2,1H3,(H,23,27);1H
2.1.3 InChI Key
GAQAKFHSULJNAK-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCOC(=O)NC1=CC2=C(C=C1)SC3=CC=CC=C3N2C(=O)CCN4CCOCC4.Cl
2.2 Other Identifiers
2.2.1 UNII
71OK3Z1ESP
2.3 Synonyms
2.3.1 MeSH Synonyms

1. En 313

2. En-313

3. En313

4. Ethmozin

5. Ethmozine

6. Etmozin

7. Hydrochloride, Moricizine

8. Moracizin

9. Moracizine

10. Moricizine

2.3.2 Depositor-Supplied Synonyms

1. 29560-58-5

2. Moracizine Hydrochloride

3. Ethmozine

4. Ethmosine

5. Moricizine Hcl

6. Moricizine (hydrochloride)

7. Ethmozin

8. Etmozin

9. 71ok3z1esp

10. Mls000830274

11. Moricizine Hydrochloride [usp]

12. En 313; Ethmosine; Ethmozin

13. En 313

14. Ethyl N-[10-(3-morpholin-4-ylpropanoyl)phenothiazin-2-yl]carbamate;hydrochloride

15. Moracizine Hcl

16. Smr000036736

17. Ethyl 10-(3-morpholinopropionyl)phenothiazine-2-carbamate, Hydrochloride

18. Dsstox_cid_27766

19. Dsstox_rid_82543

20. Dsstox_gsid_47786

21. Carbamic Acid, (10-(3-(4-morpholinyl)-l-oxopropyl)-10h-phenothiazin-2yl)-, Ethyl Ester, Hydrochloride

22. Moricizine Hydrochloride (usp)

23. Ethyl 10-(beta-n-morpholinylpropionyl)phenothiazine-2-carbamate Hydrochloride

24. Chebi:60937

25. Cas-29560-58-5

26. Ncgc00016809-01

27. Ncgc00016809-07

28. Unii-71ok3z1esp

29. Ethmozine (tn)

30. Opera_id_267

31. Ethyl 10-(3-morpholinopropionyl)phenothiazine-2-carbamate Hydrochloride

32. Cambridge Id 5229972

33. Ethyl Ether Of 10-(beta-morpholylpropionyl)phenthiazinecarbamino Acid Hydrochloride

34. Moracizinehydrochloride

35. Schembl41358

36. (10-(3-(4-morpholinyl)-1-oxopropyl)-10h-phenothiazin-2-yl)carbamic Acid, Ethyl Ester, Monohydrochloride

37. Mls000080120

38. Regid_for_cid_34632

39. Chembl1200334

40. Dtxsid1047786

41. Hy-b0615a

42. Hms1571c04

43. Ethyl 10-(3-morpholinopropanoyl)-

44. Tox21_110622

45. Moricizine Hydrochloride [mi]

46. Akos030506898

47. Tox21_110622_1

48. Ccg-221051

49. Moracizine Hydrochloride [mart.]

50. Moricizine Hydrochloride [vandf]

51. Phenothiazine-2-carbamic Acid, 10-(3-morpholinopropionyl)-, Ethyl Ester, Hydrochloride

52. Moracizine Hydrochloride [who-dd]

53. Moricizine Hydrochloride [usp-rs]

54. Ncgc00180924-01

55. Carbamic Acid, (10-(3-(4-morpholinyl)-1-oxopropyl)-10h-phenothiazin-2-yl)-, Ethyl Ester, Monohydrochloride

56. Db-047605

57. Cs-0013699

58. E-313

59. E-350

60. Ft-0630550

61. Moricizine Hydrochloride [orange Book]

62. D02087

63. Moricizine Hydrochloride [usp Impurity]

64. Sr-01000614327

65. Sr-01000614327-4

66. Q27130132

67. Ethyl N-[10-(3-morpholin-4-ylpropanoyl)phenothiazin-2-yl]carbamate;hydron;chloride

68. Carbamic Acid, N-(10-(3-(4-morpholinyl)-1-oxopropyl)-10h-phenothiazin-2-yl)-, Ethyl Ester, Hydrochloride (1:1)

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 464.0 g/mol
Molecular Formula C22H26ClN3O4S
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass463.1332552 g/mol
Monoisotopic Mass463.1332552 g/mol
Topological Polar Surface Area96.4 Ų
Heavy Atom Count31
Formal Charge0
Complexity601
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Arrhythmia Agents

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)


Voltage-Gated Sodium Channel Blockers

A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS. (See all compounds classified as Voltage-Gated Sodium Channel Blockers.)


ABOUT THIS PAGE

Looking for 29560-58-5 / Moricizine API manufacturers, exporters & distributors?

Moricizine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Moricizine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Moricizine manufacturer or Moricizine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Moricizine manufacturer or Moricizine supplier.

PharmaCompass also assists you with knowing the Moricizine API Price utilized in the formulation of products. Moricizine API Price is not always fixed or binding as the Moricizine Price is obtained through a variety of data sources. The Moricizine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Moricizine

Synonyms

29560-58-5, Moracizine hydrochloride, Ethmozine, Ethmosine, Moricizine hcl, Moricizine (hydrochloride)

Cas Number

29560-58-5

Unique Ingredient Identifier (UNII)

71OK3Z1ESP

About Moricizine

An antiarrhythmia agent used primarily for ventricular rhythm disturbances.

Moricizine Hydrochloride Manufacturers

A Moricizine Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Moricizine Hydrochloride, including repackagers and relabelers. The FDA regulates Moricizine Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Moricizine Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Moricizine Hydrochloride Suppliers

A Moricizine Hydrochloride supplier is an individual or a company that provides Moricizine Hydrochloride active pharmaceutical ingredient (API) or Moricizine Hydrochloride finished formulations upon request. The Moricizine Hydrochloride suppliers may include Moricizine Hydrochloride API manufacturers, exporters, distributors and traders.

Moricizine Hydrochloride GMP

Moricizine Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Moricizine Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Moricizine Hydrochloride GMP manufacturer or Moricizine Hydrochloride GMP API supplier for your needs.

Moricizine Hydrochloride CoA

A Moricizine Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Moricizine Hydrochloride's compliance with Moricizine Hydrochloride specifications and serves as a tool for batch-level quality control.

Moricizine Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Moricizine Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Moricizine Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Moricizine Hydrochloride EP), Moricizine Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Moricizine Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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