X
1. 2 Chlorethanol
2. 2 Chloroethyl Alcohol
3. 2-chlorethanol
4. 2-chloroethyl Alcohol
5. Alcohol, 2-chloroethyl
6. Chlorohydrin, Ethylene
7. Ethylene Chlorohydrin
8. Ethylenechlorhydrin
1. Ethylene Chlorohydrin
2. 107-07-3
3. Ethanol, 2-chloro-
4. Glycol Chlorohydrin
5. 2-chloroethyl Alcohol
6. Chloroethanol
7. Glycol Monochlorohydrin
8. 2-monochloroethanol
9. Ethylchlorohydrin
10. 2-chlorethanol
11. 2-chloro-1-ethanol
12. 2-hydroxyethyl Chloride
13. Glycomonochlorhydrin
14. Beta-chloroethyl Alcohol
15. Ethylene Chlorhydrin
16. Ethene, Chlorohydrin
17. 2-chloorethanol
18. 2-chloraethanol
19. 2-cloroetanolo
20. Beta-chloroethanol
21. Aethylenechlorhydrin
22. 2-chloro-1-hydroxyethane
23. Glicol Monocloridrina
24. Ethyleen-chloorhydrine
25. Glycolmonochloorhydrine
26. Nci-c50135
27. Ethylene Glycol, Chlorohydrin
28. Beta-hydroxyethyl Chloride
29. Chloroalcohol
30. 2-chloro-ethanol
31. Monochlorhydrine Du Glycol
32. .beta.-chloroethyl Alcohol
33. Ethanol, Chloro-
34. Nsc 122289
35. .beta.-chloroethanol
36. .beta.-hydroxyethyl Chloride
37. 753n66ihan
38. Chebi:28200
39. Nsc-122289
40. Delta-chloroethanol
41. 2-chloorethanol [dutch]
42. 2-chlorethanol [german]
43. 2-chloraethanol [german]
44. 2-cloroetanolo [italian]
45. 2-chloro Ethanol
46. Aethylenechlorhydrin [german]
47. Ccris 859
48. Ethyleen-chloorhydrine [dutch]
49. Chloroethylowy Alkohol
50. Glycolmonochloorhydrine [dutch]
51. Hsdb 426
52. Chloroethylowy Alkohol [polish]
53. Glicol Monocloridrina [italian]
54. Monochlorhydrine Du Glycol [french]
55. Einecs 203-459-7
56. Un1135
57. Brn 0878139
58. Unii-753n66ihan
59. Ai3-52326
60. 2- Chloroethanol
61. 2-chloranylethanol
62. Ethylenechlorohydrin
63. Delta-chloroethanolchloroethylowy Alkohol [polish]
64. Ethylenechlorohydrine
65. 2-choroethan-1-ol
66. Mfcd00002829
67. Ethylene Chlorohydrine
68. 2-chloroethan-1-ol
69. 2-chloroethanol (ethylene Chlorohydrin)
70. Delta-chloroethanolchloroethylowy Alkohol
71. 2-chloro-ethan-1-ol
72. Ch2clch2oh
73. 2-chloroethanol, 99%
74. 1-chloro-2-hydroxyethane
75. Dsstox_cid_1877
76. Bmse000360
77. Ec 203-459-7
78. Wln: Q2g
79. Dsstox_rid_76380
80. Dsstox_gsid_21877
81. 4-01-00-01372 (beilstein Handbook Reference)
82. 59826-67-4
83. Chembl191244
84. 2-chloroethanol [hsdb]
85. Dtxsid1021877
86. Ethylene Chlorohydrin [mi]
87. Act07200
88. Zinc8220697
89. Tox21_300043
90. Argogel(tm)-cl, 1 % Cross-linked
91. Bbl011477
92. Nsc122289
93. Stl146589
94. Akos000119040
95. Un 1135
96. Ncgc00247890-01
97. Ncgc00254022-01
98. Cas-107-07-3
99. .delta.-chloroethanolchloroethylowy Alkohol
100. 2-chloroethanol 100 Microg/ml In Methanol
101. 2-chloroethanol 1000 Microg/ml In Methanol
102. Ethylene Chlorohydrin [un1135] [poison]
103. C06753
104. 2-chloroethanol, Saj Special Grade, >=99.0%
105. A801572
106. Q209354
107. 2-chloroethanol, Pestanal(r), Analytical Standard
108. 2-chloroethanol, Puriss. P.a., >=99.0% (gc)
109. J-509022
110. Carmustine Related Compound, 2-chloroethanol-
| Molecular Weight | 80.51 g/mol |
|---|---|
| Molecular Formula | C2H5ClO |
| XLogP3 | -0.1 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 1 |
| Exact Mass | 80.0028925 g/mol |
| Monoisotopic Mass | 80.0028925 g/mol |
| Topological Polar Surface Area | 20.2 Ų |
| Heavy Atom Count | 4 |
| Formal Charge | 0 |
| Complexity | 10 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
4= VERY TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) 50-500 MG/KG, BETWEEN 1 TEASPOON & 1 OUNCE FOR 70 KG PERSON (150 LB).
Gosselin, R.E., H.C. Hodge, R.P. Smith, and M.N. Gleason. Clinical Toxicology of Commercial Products. 4th ed. Baltimore: Williams and Wilkins, 1976., p. II-119
... MAY BE ABSORBED THROUGH THE SKIN.
Sax, N.I. Dangerous Properties of Industrial Materials. 6th ed. New York, NY: Van Nostrand Reinhold, 1984., p. 712
... MAY BE ABSORBED THROUGH ... GI TRACT, OR BY INHALATION.
Grant, W. M. Toxicology of the Eye. 2nd ed. Springfield, Illinois: Charles C. Thomas, 1974., p. 266
The excretion & tissue distribution of (14)C-labeled chloroethanol were studied in rats following single oral admin of 5 & 50 mg/kg. At both dose levels, the radioactivity was rapidly eliminated, mainly in the urine. On the first day 77.2% of the dose was found in the urine, 1.7% in the feces, and 1.0% as CO2 in the expired air. Only 2.8% was excreted by these routes during the following 3 days. The residual radioactivity after 4 days was almost equally distributed. Approx 0.4% of the dose was in the liver and 3% in the whole organism.
PMID:7092566 Grunow W, Altmann HJ; Arch Toxicol 49 (3-4): 275-84 (1982)
IN VIVO, IT IS OXIDIZED TO CHLOROACETIC ACID ... .
Browning, E. Toxicity and Metabolism of Industrial Solvents. New York: American Elsevier, 1965., p. 398
2-CHLOROETHANOL WAS GIVEN ORALLY TO RATS. LIVER GLUTATHIONE WAS RAPIDLY DEPLETED & S-CARBOXYMETHYLGLUTATHIONE WAS FORMED. TOXICITY OF 2-CHLOROETHANOL IS PROBABLY DUE TO ITS CONVERSION TO CHLOROACETALDEHYDE IN VIVO.
JOHNSON MK; BIOCHEM PHARMACOL 16 (1): 185-99 (1967)
2-chloroethanol was detected in the blood and liver of rats during the first 24 days after oral dosing of CH2ClCH2Cl /ethylene dichloride/ at 750 mg/kg.
The Royal Society of Chemistry. Foreign Compound Metabolism in Mammals. Volume 6: A Review of the Literature Published during 1978 and 1979. London: The Royal Society of Chemistry, 1981., p. 335
Disposition and metabolism of 1-(2-chloroethyl)-3-(2',3',4'-tri-O-acetylribopyranosyl)-1-nitrosourea (RPCNU) were studied in rats after labeling RPCNU with (14)C- in 3 different positions. Within the first min after injection, most of the radioactivity derived from ethyl-(14)C groups was recovered as volatile products. Among these, 2-chlorothanol was identified as a main component.
PMID:6799188 Godeneche D et al; Cancer Res 42 (2): 525-9 (1982)
For more Metabolism/Metabolites (Complete) data for 2-CHLOROETHANOL (6 total), please visit the HSDB record page.
The elimination half-life and clearance value for 2-chloroethanol was 40.8 min following iv admin to beagle dogs.
PMID:7161831 Martis L et al; J Toxicol Environ Health 10 (4-5): 847-56 (1982)
Market Place
