Product Sales Data From Annual Reports of Major Pharmaceutical Companies 2016

S. No.	Company Name	Product Name	Active Ingredient	Main Therapeutic Indication	Currency	Unit	2016 Revenue in Millions	2015 Revenue in Millions	2016 Revenue in Millions (USD)	2015 Revenue in Millions (USD)	Sales Difference in Millions (USD)	Growth (%)
1	Abbvie	Humira	Adalimumab	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	16,078	14,012	16,078	14,012	2,066	15
2	Abbvie	Androgel	Testosterone	Hormonal Disorders	USD	Millions	675	694	675	694	-19	-3
3	Abbvie	Kaletra	Lopinavir/Ritonavir	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	549	700	549	700	-151	-22
4	Abbvie	Synagis	Palivizumab	Respiratory Disorders	USD	Millions	730	740	730	740	-10	-1
5	Abbvie	Lupron	Leuprolide Acetate	Oncology	USD	Millions	821	826	821	826	-5	-1
6	Abbvie	Synthroid	Levothyroxine Sodium	Hormonal Disorders	USD	Millions	763	755	763	755	8	1
7	Abbvie	Sevoflurane	Sevoflurane	Anesthetics	USD	Millions	428	474	428	474	-46	-10
8	Abbvie	Creon	Pancrelipase	Rare Diseases	USD	Millions	730	632	730	632	98	16
9	Abbvie	Duodopa	Carbidopa/Levodopa	Neurological/Mental Disorders	USD	Millions	293	231	293	231	62	27
10	Abbvie	Viekira Pak	Ombitasvir/Paritaprevir/Ritonavir	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	1,522	1,639	1,522	1,639	-117	-7
11	Abbvie	Imbruvica	Ibrutinib	Oncology	USD	Millions	1,832	754	1,832	754	1,078	143
12	Abbvie	Others			USD	Millions	1,139	1,402	1,139	1,402	-263	-19
13	Abbvie	Total Pharmaceuticals			USD	Millions	25,560	22,859	25,560	22,859	2,701	12
14	Abbvie	Other Revenues			USD	Millions	78	Not Reported	78	Not Reported	78	Not Reported
15	Abbvie	Total Sales			USD	Millions	25,638	22,859	25,638	22,859	2,779	12
16	Abbott			Pediatric	USD	Millions	3,883	3,970	3,883	3,970	-87	-2
17	Abbott			Adult	USD	Millions	3,016	3,005	3,016	3,005	11	0
18	Abbott	Total Nutrition			USD	Millions	6,899	6,975	6,899	6,975	-76	-1
19	Abbott			Core Laboratory	USD	Millions	3,844	3,707	3,844	3,707	137	4
20	Abbott			Molecular	USD	Millions	456	466	456	466	-10	-2
21	Abbott			Point of Care	USD	Millions	513	473	513	473	40	8
22	Abbott	Total Diagnostics			USD	Millions	4,813	4,646	4,813	4,646	167	4
23	Abbott	Key Emerging Markets			USD	Millions	2,912	2,781	2,912	2,781	131	5
24	Abbott	Others			USD	Millions	947	939	947	939	8	1
25	Abbott	Total Established Pharmaceuticals			USD	Millions	3,859	3,720	3,859	3,720	139	4
26	Abbott			Vascular	USD	Millions	2,896	2,792	2,896	2,792	104	4
27	Abbott			Diabetes	USD	Millions	1,142	1,117	1,142	1,117	25	2
28	Abbott			Medical Optics	USD	Millions	1,195	1,133	1,195	1,133	62	5
29	Abbott	Total Medical Devices			USD	Millions	5,233	5,042	5,233	5,042	191	4
30	Abbott	Other Sales			USD	Millions	49	22	49	22	27	123
31	Abbott	Total Sales			USD	Millions	20,853	20,405	20,853	20,405	448	2
32	Actelion	Opsumit	Macitentan	Cardiovascular Diseases	CHF	Millions	831	516	823	511	312	61
33	Actelion	Tracleer	Bosentan	Cardiovascular Diseases	CHF	Millions	1,020	1,212	1,010	1,200	-190	-16
34	Actelion	Uptravi	Selexipag	Cardiovascular Diseases	CHF	Millions	245	Not Reported	243	Not Reported	243	New Launch
35	Actelion	Veletri	Epoprostenol	Cardiovascular Diseases	CHF	Millions	97	83	96	82	14	17
36	Actelion	Ventavis	Iloprost	Cardiovascular Diseases	CHF	Millions	73	105	72	104	-32	-30
37	Actelion	Valchlor	Mechlorethamine	Oncology	CHF	Millions	35	27	35	27	8	30
38	Actelion	Zavesca	Miglustat	Rare Diseases	CHF	Millions	104	92	103	91	12	13
39	Actelion	Others			CHF	Millions	8	7	8	7	1	14
40	Actelion	Total Pharmaceutical Sale			CHF	Millions	2,412	2,042	2,388	2,022	366	18
41	Actelion	Contract Revenue			CHF	Millions	6	4	6	4	2	50
42	Actelion	Total Sale			CHF	Millions	2,418	2,046	2,394	2,026	368	18
43	Alexion	Soliris	Eculizumab	Blood Disorders	USD	Millions	2,843	2,591	2,843	2,591	252	10
44	Alexion	Strensiq	Asfotase Alfa	Metabolic Disorders	USD	Millions	210	12	210	12	198	1,650
45	Alexion	Kanuma	Sebelipase Alfa	Metabolic Disorders	USD	Millions	29	Not Reported	29	Not Reported	29	New Launch
46	Alexion	Others			USD	Millions	2	1	2	1	1	100
47	Alexion	Total Net Product Sales			USD	Millions	3,084	2,604	3,084	2,604	480	18
48	Allergan	Botox	Onabotulinumtoxina	Urology	USD	Millions	2,786	1,971	2,786	1,971	815	41
49	Allergan	Restasis	Cyclosporine	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	1,488	1,048	1,488	1,048	440	42
50	Allergan	Fillers			USD	Millions	867	574	867	574	293	51
51	Allergan	Lumigan/Ganfort	Bimatoprost	Ophthalmology	USD	Millions	688	544	688	544	144	26
52	Allergan	Linzess/Constella	Linaclotide	Gastrointestinal Disorders	USD	Millions	643	459	643	459	184	40
53	Allergan	Bystolic/Byvalson	Nebivolol	Cardiovascular Diseases	USD	Millions	641	646	641	646	-5	-1
54	Allergan	Namenda XR	Memantine Hydrochloride	Alzheimer Diseases	USD	Millions	628	759	628	759	-131	-17
55	Allergan	Alphagan/Combigan	Brimonidine Tartrate/Timolol Maleate	Ophthalmology	USD	Millions	546	411	546	411	135	33
56	Allergan	Eye Drops		Ophthalmology	USD	Millions	463	398	463	398	65	16
57	Allergan	Asacol/Delzicol	Mesalazine	Gastrointestinal Disorders	USD	Millions	415	618	415	618	-203	-33
58	Allergan	Lo Loestrin	Norethindrone Acetate/Ethinyl Estradiol	Contraception	USD	Millions	404	350	404	350	54	15
59	Allergan	Estracecream	Estradiol	Reproductive System Diseases	USD	Millions	379	326	379	326	53	16
60	Allergan	Breast Implants			USD	Millions	356	301	356	301	55	18
61	Allergan	Viibryd/Fetzima	Vilazodone	Neurological/Mental Disorders	USD	Millions	342	328	342	328	14	4
62	Allergan	Minastrin24	Ethinyl Estradiol, Norethindrone	Contraception	USD	Millions	327	273	327	273	54	20
63	Allergan	Ozurdex	Dexamethasone	Ophthalmology	USD	Millions	263	168	263	168	95	57
64	Allergan	Carafate/Sulcrate	Sucralfate	Gastrointestinal Disorders	USD	Millions	231	213	231	213	18	8
65	Allergan	Aczone	Dapsone	Dermatology	USD	Millions	217	171	217	171	46	27
66	Allergan	Zenpep	Pancrelipase	Gastrointestinal Disorders	USD	Millions	201	167	201	167	34	20
67	Allergan	Canasa/Salofalk	Mesalazine	Gastrointestinal Disorders	USD	Millions	196	156	196	156	40	26
68	Allergan	Saphris	Asenapine	Neurological/Mental Disorders	USD	Millions	167	187	167	187	-20	-11
69	Allergan	Armour Thyroid	Thyroid Extract	Hypothyroidism	USD	Millions	167	131	167	131	36	27
70	Allergan	Teflaro	Ceftaroline	Dermatology	USD	Millions	134	138	134	138	-4	-3
71	Allergan	Rapaflo	Silodosin	Renal Disorders	USD	Millions	122	126	122	126	-4	-3
72	Allergan	Skinmedica		Dermatology	USD	Millions	108	77	108	77	31	40
73	Allergan	Savella	Milnacipran Hcl	Fibromyalgia	USD	Millions	103	106	103	106	-3	-3
74	Allergan	Tazorac	Tazarotene	Dermatology	USD	Millions	96	94	96	94	2	2
75	Allergan	Vraylar	Cariprazine	Neurological/Mental Disorders	USD	Millions	94	Not Reported	94	Not Reported	94	New Launch
76	Allergan	Viberzi	Eluxadoline	Gastrointestinal Disorders	USD	Millions	93	12	93	12	81	675
77	Allergan	Latisse	Bimatoprost	Hypotrichosis of Eyelashes	USD	Millions	86	73	86	73	13	18
78	Allergan	Lexapro	Escitalopram Oxalate	Neurological/Mental Disorders	USD	Millions	67	72	67	72	-5	-7
79	Allergan	Namzaric	Memantine And Donepezil Hydrochloride	Neurological/Mental Disorders	USD	Millions	58	11	58	11	47	427
80	Allergan	Kybella/Belkyra	Deoxycholic Acid	Submental Fat	USD	Millions	53	3	53	3	50	1,667
81	Allergan	Dalvance	Dalbavancin	Dermatology	USD	Millions	39	17	39	17	22	129
82	Allergan	Avycaz	Ceftazidime And Avibactam	Gastrointestinal Disorders	USD	Millions	36	23	36	23	13	57
83	Allergan	Liletta	Levonorgestrel	Contraception	USD	Millions	23	15	23	15	8	53
84	Allergan	Enablex	Darifenacin	Renal Disorders	USD	Millions	17	69	17	69	-52	-75
85	Allergan	Namenda IR	Memantine Hydrochloride	Alzheimer Diseases	USD	Millions	15	556	15	556	-541	-97
86	Allergan	Other Revenues			USD	Millions	1,091	1,256	1,091	1,256	-165	-13
87	Allergan	Less Product Sold Through Our Former ANDA Distribution Business			USD	Millions	-80	-157	-80	-157	77	-49
88	Allergan	Total Net Revenues			USD	Millions	14,571	12,688	14,571	12,688	1,883	15
89	Amgen	Neulasta	Pegfilgrastim	Blood Disorders	USD	Millions	4,648	4,715	4,648	4,715	-67	-1
90	Amgen	Neupogen	Filgrastim	Blood Disorders	USD	Millions	765	1,049	765	1,049	-284	-27
91	Amgen	Enbrel	Etanercept	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	5,965	5,364	5,965	5,364	601	11
92	Amgen	Xgeva	Denosumab	Oncology	USD	Millions	1,529	1,405	1,529	1,405	124	9
93	Amgen	Prolia	Denosumab	Bone Health	USD	Millions	1,635	1,312	1,635	1,312	323	25
94	Amgen	Epogen	Epoetin Alfa	Blood Disorders	USD	Millions	1,282	1,856	1,282	1,856	-574	-31
95	Amgen	Aranesp	Darbepoetin Alfa	Blood Disorders	USD	Millions	2,093	1,951	2,093	1,951	142	7
96	Amgen	Sensipar/ Mimpara	Cinacalcet	Hormonal Disorders	USD	Millions	1,582	1,415	1,582	1,415	167	12
97	Amgen	Vectibix	Panitumumab	Oncology	USD	Millions	611	549	611	549	62	11
98	Amgen	Nplate	Romiplostim	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	584	525	584	525	59	11
99	Amgen	Kyprolis	Carfilzomib	Oncology	USD	Millions	692	512	692	512	180	35
100	Amgen	Blincyto	Blinatumomab	Oncology	USD	Millions	115	77	115	77	38	49
101	Amgen	Repatha	Evolocumab	Cardiovascular Diseases	USD	Millions	141	10	141	10	131	1,310
102	Amgen	Others			USD	Millions	250	204	250	204	46	23
103	Amgen	Total Pharmaceuticals			USD	Millions	21,892	20,944	21,892	20,944	948	5
104	Amgen	Other Revenues			USD	Millions	1,099	718	1,099	718	381	53
105	Amgen	Total Revenues			USD	Millions	22,991	21,662	22,991	21,662	1,329	6
106	Astellas	Symbicort	Budesonide and Formoterol	Respiratory Disorders	Yen	Millions	38,400	36,900	346	332	14	4
107	Astellas	Xtandi	Enzalutamide	Oncology	Yen	Millions	253,200	231,100	2,279	2,080	199	10
108	Astellas	Lipitor	Atorvastatin Calcium	Cardiovascular Diseases	Yen	Millions	24,600	34,700	221	312	-91	-29
109	Astellas	Prograf	Tacrolimus	Immunology (Organ Transplant, Arthritis etc.)	Yen	Millions	188,300	204,400	1,695	1,840	-145	-8
110	Astellas	Vesicare	Solifenacin Succinate	Urology	Yen	Millions	120,100	135,800	1,081	1,222	-141	-12
111	Astellas	Ambisome	Amphotericin B	Infectious Diseases (HIV, Hepatitis etc.)	Yen	Millions	10,500	10,600	95	95	-1	-1
112	Astellas	Micardis	Telmisartan	Cardiovascular Diseases	Yen	Millions	93,700	97,500	843	878	-34	-4
113	Astellas	Betanis/Myrbetriq/Betmiga	Mirabegron	Renal Disorders	Yen	Millions	93,200	75,400	839	679	160	24
114	Astellas	Seroquel	Quetiapine Fumarate	Neurological/Mental Disorders	Yen	Millions	8,000	11,100	72	100	-28	-28
115	Astellas	Adenoscan/Lexiscan	Adenosine/Regadenoson	Diagnostic	Yen	Millions	69,900	75,800	629	682	-53	-8
116	Astellas	Myslee	Zolpidem	Sleep Disorders	Yen	Millions	15,300	18,500	138	167	-29	-17
117	Astellas	celecox	Celecoxib	Anti-Inflammatory	Yen	Millions	47,600	46,400	428	418	11	3
118	Astellas	Harnal/Omnic	Tamsulosin	Renal Disorders	Yen	Millions	47,300	54,900	426	494	-68	-14
119	Astellas	Funguard/Mycamine	Micafungin sodium	Anti-fungal	Yen	Millions	40,300	41,000	363	369	-6	-2
120	Astellas	Tarceva	Erlotinib	Oncology	Yen	Millions	36,800	49,200	331	443	-112	-25
121	Astellas	Vaccines	Vaccines	Vaccines	Yen	Millions	34,100	43,900	307	395	-88	-22
122	Astellas	Eligard	Leuprorelin	Oncology	Yen	Millions	16,000	18,100	144	163	-19	-12
123	Astellas	Protopic	Tacrolimus	Immunology	Yen	Millions	3,500	15,800	32	142	-111	-78
124	Astellas	Bonoteo	Minodronic acid	Oesteoprosis	Yen	Millions	13,900	14,200	125	128	-3	-2
125	Astellas	Gaster	Famotidine	Gastrointestinal Disorders	Yen	Millions	11,400	15,600	103	140	-38	-27
126	Astellas	Geninax	Garenoxacin	Anti-Bacterial	Yen	Millions	10,100	10,900	91	98	-7	-7
127	Astellas	Suglat	Ipragliflozin	Diabetes	Yen	Millions	9,100	6,300	82	57	25	44
128	Astellas	Cimzia	Certolizumab pegol	Anti-Inflammatory	Yen	Millions	7,600	6,200	68	56	13	23
129	Astellas	Argamate	Calcium polystyrene sulphonate	Hyperkalemia	Yen	Millions	5,900	6,100	53	55	-2	-3
130	Astellas	Cresemba	Isavuconazonium sulfate	Anti-fungal	Yen	Millions	5,000	1,590	45	14	31	214
131	Astellas	Gonax	Degarelix acetate	Oncology	Yen	Millions	4,300	3,800	39	34	5	13
132	Astellas	Dificlir	Fidaxomicin	Infectious Diseases (HIV, Hepatitis etc.)	Yen	Millions	2,200	2,500	20	23	-3	-12
133	Astellas	Qutenza	Capasaicin	Neuropathic pain	Yen	Millions	2,000	2,100	18	19	-1	-5
134	Astellas	Kiklin	Bixalomer	Renal Disorders	Yen	Millions	1,600	1,500	14	14	1	7
135	Astellas	Cefzon			Yen	Millions	Not Reported	1,100	Not Reported	10	-10	-100
136	Astellas	Total Sales			Yen	Millions	1,312,600	1,360,200	11,813	12,242	-428	-3
137	AstraZeneca	Crestor	Rosuvastatin Calcium	Cardiovascular Diseases	USD	Millions	3,401	5,017	3,401	5,017	-1,616	-32
138	AstraZeneca	Seloken/Toprol-XL	Metoprolol Hydrochloride	Cardiovascular Diseases	USD	Millions	737	710	737	710	27	4
139	AstraZeneca	Onglyza/Kombiglyze XR/Komboglyze	Saxagliptin/Saxagliptin+Metoprolol Hydrochloride	Diabetes	USD	Millions	720	786	720	786	-66	-8
140	AstraZeneca	Atacand	Candesartan	Cardiovascular Diseases	USD	Millions	315	358	315	358	-43	-12
141	AstraZeneca	Brilinta/Brilique	Ticagrelor	Cardiovascular Diseases	USD	Millions	839	619	839	619	220	36
142	AstraZeneca	Byetta	Exenatide	Diabetes	USD	Millions	254	316	254	316	-62	-20
143	AstraZeneca	Bydureon	Exenatide	Diabetes	USD	Millions	578	580	578	580	-2	0
144	AstraZeneca	Farxiga/Forxiga	Dapagliflozin	Diabetes	USD	Millions	835	492	835	492	343	70
145	AstraZeneca	Plendil, Tenormin and others	Felodipine, Atenolol	Cardiovascular Diseases	USD	Millions	437	611	437	611	-174	-28
146	AstraZeneca	Total Cardiovascular And Metabolic Diseases			USD	Millions	8,116	9,489	8,116	9,489	-1,373	-14
147	AstraZeneca	Zoladex	Goserelin Acetate	Oncology	USD	Millions	816	816	816	816	0	0
148	AstraZeneca	Faslodex	Fulvestrant	Oncology	USD	Millions	830	704	830	704	126	18
149	AstraZeneca	Iressa	Gefitinib	Oncology	USD	Millions	513	543	513	543	-30	-6
150	AstraZeneca	Arimidex	Anastrozole	Oncology	USD	Millions	232	250	232	250	-18	-7
151	AstraZeneca	Casodex	Bicalutamide	Oncology	USD	Millions	247	267	247	267	-20	-7
152	AstraZeneca	Lynparza	Olaparib	Oncology	USD	Millions	218	94	218	94	124	132
153	AstraZeneca	Tagrisso	Osimertinib	Oncology	USD	Millions	423	19	423	19	404	2,126
154	AstraZeneca	Other Products			USD	Millions	104	132	104	132	-28	-21
155	AstraZeneca	Total Oncology			USD	Millions	3,383	2,825	3,383	2,825	558	20
156	AstraZeneca	Symbicort	Budesonide And Formoterol	Respiratory Disorders	USD	Millions	2,989	3,394	2,989	3,394	-405	-12
157	AstraZeneca	Pulmicort	Budesonide	Respiratory Disorders	USD	Millions	1,061	1,014	1,061	1,014	47	5
158	AstraZeneca	Tudorza/Eklira	Aclidinium Bromide	Respiratory Disorders	USD	Millions	170	190	170	190	-20	-11
159	AstraZeneca	Daliresp/Daxas	Roflumilast	Respiratory Disorders	USD	Millions	154	104	154	104	50	48
160	AstraZeneca	Duaklir	Aclidinium Bromide/Formoterol Fumarate	Respiratory Disorders	USD	Millions	63	27	63	27	36	133
161	AstraZeneca	Other Products			USD	Millions	316	258	316	258	58	22
162	AstraZeneca	Total Respiratory, Inflammation And Autoimmunity			USD	Millions	4,753	4,987	4,753	4,987	-234	-5
163	AstraZeneca	Synagis	Palivizumab	Respiratory Disorders	USD	Millions	677	662	677	662	15	2
164	AstraZeneca	Flumist/Fluenz	Influenza Vaccine Live, Intranasal	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	104	288	104	288	-184	-64
165	AstraZeneca	Movantik/Moventig	Naloxegol	Gastrointestinal Disorders	USD	Millions	91	29	91	29	62	214
166	AstraZeneca	Seroquel XR	Quetiapine Fumarate	Neurological/Mental Disorders	USD	Millions	735	1,025	735	1,025	-290	-28
167	AstraZeneca	Nexium	Esomeprazole Magnesium	Gastrointestinal Disorders	USD	Millions	2,032	2,496	2,032	2,496	-464	-19
168	AstraZeneca	Losec/Prilosec	Omeprazole	Gastrointestinal Disorders	USD	Millions	276	340	276	340	-64	-19
169	AstraZeneca	Local Anaesthetics, Seroquel IR, Merrem, Diprivan and other Products			USD	Millions	1,152	1,500	1,152	1,500	-348	-23
170	AstraZeneca	Total Other			USD	Millions	5,067	6,340	5,067	6,340	-1,273	-20
171	AstraZeneca	Total Pharmaceuticals			USD	Millions	21,319	23,641	21,319	23,641	-2,322	-10
172	AstraZeneca	Total Externalisation Revenue			USD	Millions	1,683	1,067	1,683	1,067	616	58
173	AstraZeneca	Total Pharmaceuticals			USD	Millions	23,002	24,708	23,002	24,708	-1,706	-7
174	Baxter			Renal	USD	Millions	3,855	3,789	3,855	3,789	66	2
175	Baxter			Hospital Products	USD	Millions	6,308	6,179	6,308	6,179	129	2
176	Baxter	Total Revenue			USD	Millions	10,163	9,968	10,163	9,968	195	2
177	Bayer	Xarelto	Rivaroxaban	Cardiovascular Diseases	Euro	Millions	2,928	2,252	3,104	2,387	717	30
178	Bayer	Kogenate	Antihemophilic Factor (Recombinant)	Rare Diseases	Euro	Millions	1,166	1,155	1,236	1,224	12	1
179	Bayer	Betaferon/Betaseron	Interferon Beta-1B	Neurological/Mental Disorders	Euro	Millions	734	824	778	873	-95	-11
180	Bayer	Mirena Product Family	Levonorgestrel	Sexual Health	Euro	Millions	1,043	968	1,106	1,026	80	8
181	Bayer	Nexavar	Sorafenib	Oncology	Euro	Millions	870	892	922	946	-23	-2
182	Bayer	Yaz/Yasim/Yasminelle	Drospirenone And Ethinyl Estradiol	Sexual Health	Euro	Millions	678	706	719	748	-30	-4
183	Bayer	Eylea	Aflibercept	Ophthalmology	Euro	Millions	1,625	1,228	1,723	1,302	421	32
184	Bayer	Adalat	Nifedipine	Cardiovascular Diseases	Euro	Millions	624	633	661	671	-10	-1
185	Bayer	Aspirin Cardio	Acetylsalicylic Acid	Cardiovascular Diseases	Euro	Millions	538	524	570	555	15	3
186	Bayer	Xofigo	Radium Ra 223 Dichloride	Oncology	Euro	Millions	331	257	351	272	78	29
187	Bayer	Glucobay	Acarbose	Diabetes	Euro	Millions	515	523	546	554	-8	-2
188	Bayer	Avalox/Avelox	Moxifloxacin Hydrochloride	Anti-Bacterial	Euro	Millions	353	379	374	402	-28	-7
189	Bayer	Stivarga	Regorafenib	Oncology	Euro	Millions	275	313	292	332	-40	-12
190	Bayer	Gadavist/Gadovist	Ezetimibe	Cardiovascular Diseases	Euro	Millions	346	290	367	307	59	19
191	Bayer	Ultravist	Iopromide	Iodinated Contrast Agent	Euro	Millions	316	318	335	337	-2	-1
192	Bayer	Total Pharmaceuticals			Euro	Millions	16,420	15,308	17,405	16,226	1,179	7
193	Bayer			Consumer Health	Euro	Millions	6,037	6,076	6,399	6,441	-41	-1
194	Bayer			Crop Science	Euro	Millions	9,915	10,128	10,510	10,736	-226	-2
195	Bayer			Animal Health	Euro	Millions	1,523	1,490	1,614	1,579	35	2
196	Bayer	Total Life Science (Incl. Reconciliation)			Euro	Millions	34,943	34,103	37,040	36,149	890	2
197	Bayer	Covestro			Euro	Millions	11,826	11,982	12,536	12,701	-165	-1
198	Bayer	Total Group Sales			Euro	Millions	46,769	46,085	49,575	48,850	725	1
199	Biogen	Tecfidera	Dimethyl Fumarate	Neurological/Mental Disorders	USD	Millions	3,968	3,638	3,968	3,638	330	9
200	Biogen	Avonex	Interferon Beta-1A	Neurological/Mental Disorders	USD	Millions	2,314	2,630	2,314	2,630	-316	-12
201	Biogen	Plegridy	Peginterferon Beta-1A	Neurological/Mental Disorders	USD	Millions	482	339	482	339	143	42
202	Biogen	Tysabri	Natalizumab	Neurological/Mental Disorders	USD	Millions	1,964	1,886	1,964	1,886	78	4
203	Biogen	Fampyra	Fampridine	Neurological/Mental Disorders	USD	Millions	85	90	85	90	-5	-6
204	Biogen	Zinbryta	Daclizumab	Neurological/Mental Disorders	USD	Millions	8	Not Reported	8	Not Reported	8	New Launch
205	Biogen	Total Multiple Sclerosis			USD	Millions	8,820	8,583	8,820	8,583	237	3
206	Biogen	Eloctate	Antihemophilic Factor (Recombinant), Fc Fusion Protein	Blood Disorders	USD	Millions	513	320	513	320	193	60
207	Biogen	Alprolix	Coagulation Factor Ix (Recombinant), Fc Fusion Protein	Blood Disorders	USD	Millions	334	235	334	235	99	42
208	Biogen	Total Hemophilia			USD	Millions	847	554	847	554	293	53
209	Biogen	Spinraza	Nusinersen	Spinal Muscular Atrophy	USD	Millions	5	Not Reported	5	Not Reported	5	New Launch
210	Biogen	Benepali	Etanercept	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	101	Not Reported	101	Not Reported	101	New Launch
211	Biogen	Flixabi	Infliximab	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	0.1	Not Reported	0.1	Not Reported	0	New Launch
212	Biogen	Fumaderm	Fumapharm Ag	Anti-Fungal	USD	Millions	46	51	46	51	-5	-10
213	Biogen	Total Other Product Revenues			USD	Millions	151	51	151	51	100	196
214	Biogen	Total Product Revenues			USD	Millions	9,818	9,189	9,818	9,189	629	7
215	Biogen	Anti-Cd20 Revenues			USD	Millions	1,315	1,339	1,315	1,339	-24	-2
216	Biogen	Other Revenues			USD	Millions	316	236	316	236	80	34
217	Biogen	Total Sales			USD	Millions	11,449	10,764	11,449	10,764	685	6
218	Boehringer Ingelheim	Spiriva	Tiotropium Bromide	Respiratory Disorders	Euro	Millions	2,995	3,553	3,175	3,766	-591	-16
219	Boehringer Ingelheim	Pradaxa	Dabigatran Etexilate	Blood Disorders	Euro	Millions	1,385	1,287	1,468	1,364	104	8
220	Boehringer Ingelheim	Micardis	Telmisartan	Cardiovascular Diseases	Euro	Millions	959	956	1,017	1,013	3	0
221	Boehringer Ingelheim	Trajenta/Jentadueto	Linagliptin	Diabetes	Euro	Millions	1,128	909	1,196	964	232	24
222	Boehringer Ingelheim	Prescription Medicines			Euro	Millions	12,036	11,201	12,758	11,873	885	7
223	Boehringer Ingelheim	Dulcolax	Sodium Picosulphate	Gastrointestinal Disorders	Euro	Millions	237	225	251	239	13	5
224	Boehringer Ingelheim	Buscopan	Hyoscine Butylbromide	Anti-Inflammatory	Euro	Millions	236	223	250	236	14	6
225	Boehringer Ingelheim	Mucosolvan	Ambroxol	Respiratory Disorders	Euro	Millions	136	168	144	178	-34	-19
226	Boehringer Ingelheim	Pharmaton	Multivitamins	Dietary Supplement	Euro	Millions	145	140	154	148	5	4
227	Boehringer Ingelheim	Consumer Healthcare			Euro	Millions	1,578	1,513	1,673	1,604	69	4
228	Boehringer Ingelheim	Ingelvac Circo?ex	PCV2 Vaccine	Vaccines	Euro	Millions	283	281	300	298	2	1
229	Boehringer Ingelheim	Metacam	Meloxicam	Anti-Inflammatory	Euro	Millions	106	101	112	107	5	5
230	Boehringer Ingelheim	Ingelvac Prrs	Modified-Live Prrs Vaccine	Vaccines	Euro	Millions	114	99	121	105	16	15
231	Boehringer Ingelheim	Duramune	Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine	Vaccines	Euro	Millions	100	88	106	93	13	14
232	Boehringer Ingelheim	Animal Health			Euro	Millions	1,460	1,363	1,548	1,445	103	7
233	Boehringer Ingelheim	Biopharmaceuticals			Euro	Millions	613	576	650	611	39	6
234	Boehringer Ingelheim	Industrial Customers And Other Sales			Euro	Millions	163	145	173	154	19	12
235	Boehringer Ingelheim	Total Sales			Euro	Millions	15,850	14,798	16,801	15,686	1,115	7
236	Bristol Myers Squibb	Baraclude	Entecavir	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	1,192	1,312	1,192	1,312	-120	-9
237	Bristol Myers Squibb	Hepatits C Franchise	Daclatasvir And Asunaprevir	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	1,578	1,603	1,578	1,603	-25	-2
238	Bristol Myers Squibb	Reyataz	Atazanavir Sulphate	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	912	1,139	912	1,139	-227	-20
239	Bristol Myers Squibb	Sustiva	Efavirenz	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	1,065	1,252	1,065	1,252	-187	-15
240	Bristol Myers Squibb	Total Virology			USD	Millions	4,747	5,306	4,747	5,306	-559	-11
241	Bristol Myers Squibb	Empliciti	Elotuzumab	Oncology	USD	Millions	150	3	150	3	147	4,900
242	Bristol Myers Squibb	Erbitux	Cetuximab	Oncology	USD	Millions	Not Reported	501	Not Reported	501	-501	-100
243	Bristol Myers Squibb	Opdivo	Nivolumab	Oncology	USD	Millions	3,774	942	3,774	942	2,832	301
244	Bristol Myers Squibb	Sprycel	Dasatinib	Oncology	USD	Millions	1,824	1,620	1,824	1,620	204	13
245	Bristol Myers Squibb	Yervoy	Ipilimumab	Oncology	USD	Millions	1,053	1,126	1,053	1,126	-73	-6
246	Bristol Myers Squibb	Total Oncology			USD	Millions	6,801	4,192	6,801	4,192	2,609	62
247	Bristol Myers Squibb	Abilify	Aripiprazole	Neurological/Mental Disorders	USD	Millions	128	746	128	746	-618	-83
248	Bristol Myers Squibb	Total Neuroscience			USD	Millions	128	746	128	746	-618	-83
249	Bristol Myers Squibb	Orencia	Abatacept	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	2,265	1,885	2,265	1,885	380	20
250	Bristol Myers Squibb	Total Immunoscience			USD	Millions	2,265	1,885	2,265	1,885	380	20
251	Bristol Myers Squibb	Eliquis	Apixaban	Blood Disorders	USD	Millions	3,343	1,860	3,343	1,860	1,483	80
252	Bristol Myers Squibb	Total Cardiovascular			USD	Millions	3,343	1,860	3,343	1,860	1,483	80
253	Bristol Myers Squibb	Total Other Mature Products			USD	Millions	2,143	2,571	2,143	2,571	-428	-17
254	Bristol Myers Squibb	Total Excluding Diabetes Alliance			USD	Millions	Not Reported	16,364	Not Reported	16,364	-16,364	-100
255	Bristol Myers Squibb	Total Pharmaceuticals			USD	Millions	19,427	16,560	19,427	16,560	2,867	17
256	Celgene	Revlimid	Lenalidomide	Oncology	USD	Millions	6,974	5,801	6,974	5,801	1,173	20
257	Celgene	Abraxane	Paclitaxel Protein-Bound	Oncology	USD	Millions	973	968	973	968	5	1
258	Celgene	Pomalyst/Imnovid	Pomalidomide	Oncology	USD	Millions	1,311	983	1,311	983	328	33
259	Celgene	Otezla	Apremilast	Dermatology	USD	Millions	1,017	472	1,017	472	545	115
260	Celgene	Vidaza	Azacitidine	Oncology	USD	Millions	608	591	608	591	17	3
261	Celgene	Azacitidine For Injection	Azacitidine	Oncology	USD	Millions	66	84	66	84	-18	-21
262	Celgene	Thalomid	Thalidomide	Oncology	USD	Millions	152	185	152	185	-33	-18
263	Celgene	Istodax	Romidepsin	Oncology	USD	Millions	79	69	79	69	10	14
264	Celgene	Others			USD	Millions	4	8	4	8	-4	-50
265	Celgene	Total Net Product Sales			USD	Millions	11,185	9,161	11,185	9,161	2,024	22
266	Celgene	Other Revenues			USD	Millions	45	95	45	95	-50	-53
267	Celgene	Total Revenues			USD	Millions	11,229	9,256	11,229	9,256	1,973	21
268	Chugai			Oncology	Yen	Millions	220,300	215,700	1,983	1,941	41	2
269	Chugai			Bone And Joint Diseases	Yen	Millions	86,100	79,400	775	715	60	8
270	Chugai			Renal Disorders	Yen	Millions	41,100	45,400	370	409	-39	-9
271	Chugai			Immunology (Organ Transplant, Arthritis etc.)	Yen	Millions	13,700	15,900	123	143	-20	-14
272	Chugai	Others			Yen	Millions	18,500	21,700	167	195	-29	-15
273	Chugai	Overseas			Yen	Millions	79,500	82,200	716	740	-24	-3
274	Chugai	Domestic Sales (Excluding Tamiflu)			Yen	Millions	379,700	378,000	3,417	3,402	15	0
275	Chugai	Tamiflu Sales	Oseltamivir Phosphate	Anti-Viral	Yen	Millions	13,500	8,200	122	74	48	65
276	Chugai	Total Sales			Yen	Millions	472,700	468,400	4,254	4,216	39	1
277	Chugai	Royalties And Other Operating Income			Yen	Millions	19,100	30,400	172	274	-102	-37
278	Chugai	Total Revenues			Yen	Millions	491,800	498,800	4,426	4,489	-63	-1
279	Dainippon Sumitomo	Surepost	Repaglinide	Diabetes	Yen	Millions	4,200	3,400	38	31	7	24
280	Dainippon Sumitomo	Ambisome	Amphotericin B	Anti-fungal	Yen	Millions	4,500	4,200	41	38	3	7
281	Dainippon Sumitomo	Lunesta	Eszopiclone	Sleep Disorders	Yen	Millions	200	5,500	2	50	-48	-96
282	Dainippon Sumitomo	Xopenex	Levalbuterol	Respiratory Disorders	Yen	Millions	5,600	6,800	50	61	-11	-18
283	Dainippon Sumitomo	Ciclesonide	Ciclesonide	Respiratory Disorders	Yen	Millions	5,300	6,900	48	62	-14	-23
284	Dainippon Sumitomo	Aptiom	Eslicarbazepine	Neurological/Mental Disorders	Yen	Millions	10,200	6,300	92	57	35	62
285	Dainippon Sumitomo	Replagal	Agalsidase alfa	Renal Disorders	Yen	Millions	10,600	10,100	95	91	5	5
286	Dainippon Sumitomo	Avapro	Irbesartan	Cardiovascular Diseases	Yen	Millions	10,500	11,100	95	100	-5	-5
287	Dainippon Sumitomo	Lonasen	Blonanserin	Neurological/Mental Disorders	Yen	Millions	12,900	12,800	116	115	1	1
288	Dainippon Sumitomo	Trerief/Excegran	Zonisamide	Neurological/Mental Disorders	Yen	Millions	14,700	13,300	132	120	13	11
289	Dainippon Sumitomo	Metgluco	Biguanide	Diabetes	Yen	Millions	11,400	16,300	103	147	-44	-30
290	Dainippon Sumitomo	Aimix	Amlodipine, Irbesartan	Cardiovascular Diseases	Yen	Millions	16,100	14,800	145	133	12	9
291	Dainippon Sumitomo	Amlodin	Amlodipine	Cardiovascular Diseases	Yen	Millions	13,700	17,500	123	158	-34	-22
292	Dainippon Sumitomo	Brovana	Arformoterol	Respiratory Disorders	Yen	Millions	32,500	28,800	293	259	33	13
293	Dainippon Sumitomo	Latuda	Lurasidone	Neurological/Mental Disorders	Yen	Millions	128,700	112,000	1,158	1,008	150	15
294	Dainippon Sumitomo	Meropen	Meropenem Hydrate	Anti-bacterial	Yen	Millions	27,200	28,400	245	256	-11	-4
295	Dainippon Sumitomo	Gasmotin	Mosapride Citrate	Gastrointestinal Disorders	Yen	Millions	6,500	9,100	59	82	-23	-29
296	Dainippon Sumitomo	Prorenal	limaprost alfadex	Neurological/Mental Disorders	Yen	Millions	7,000	9,300	63	84	-21	-25
297	Dainippon Sumitomo	Ebastel	Ebastine	Anti-Allergic	Yen	Millions	1,000	3,400	9	31	-22	-71
298	Dainippon Sumitomo	Total Sales			Yen	Millions	404,200	396,770	3,638	3,571	67	2
299	Eli Lilly	Zyprexa	Olanzapine	Neurological/Mental Disorders	USD	Millions	725	940	725	940	-215	-23
300	Eli Lilly	Cymbalta	Duloxetine	Neurological/Mental Disorders	USD	Millions	931	1,028	931	1,028	-97	-9
301	Eli Lilly	Strattera	Atomoxetine	Neurological/Mental Disorders	USD	Millions	855	784	855	784	71	9
302	Eli Lilly	Prozac	Fluoxetine	Neurological/Mental Disorders	USD	Millions	182	155	182	155	27	17
303	Eli Lilly	Amyvid	Florbetapir	Neurological/Mental Disorders	USD	Millions	Not Reported	6	Not Reported	6	-6	-100
304	Eli Lilly	Other Neuroscience			USD	Millions	28	23	28	23	5	22
305	Eli Lilly	Total Neuroscience			USD	Millions	2,720	2,935	2,720	2,935	-215	-7
306	Eli Lilly	Taltz	Ixekizumab	Dermatology	USD	Millions	113	Not Reported	113	Not Reported	113	New Launch
307	Eli Lilly	Total Immunology			USD	Millions	113	Not Reported	113	Not Reported	113	Not Reported
308	Eli Lilly	Humalog	Insulin Lispro	Diabetes	USD	Millions	2,769	2,842	2,769	2,842	-73	-3
309	Eli Lilly	Humulin	Insulin Isophane	Diabetes	USD	Millions	1,366	1,307	1,366	1,307	59	5
310	Eli Lilly	Evista	Raloxifene	Bone Health	USD	Millions	173	237	173	237	-64	-27
311	Eli Lilly	Forteo	Teriparatide	Bone Health	USD	Millions	1,500	1,348	1,500	1,348	152	11
312	Eli Lilly	Humatrope	Somatropin	Hormonal Disorders	USD	Millions	304	312	304	312	-8	-3
313	Eli Lilly	Axiron	Testosterone	Hormonal Disorders	USD	Millions	145	155	145	155	-10	-6
314	Eli Lilly	Glucagon	Rdna Origin	Diabetes	USD	Millions	133	121	133	121	12	10
315	Eli Lilly	Trajenta	Linagliptin	Diabetes	USD	Millions	437	357	437	357	80	22
316	Eli Lilly	Jardiance	Empagliflozin	Diabetes	USD	Millions	202	60	202	60	142	237
317	Eli Lilly	Trulicity	Dulaglutide	Diabetes	USD	Millions	926	249	926	249	677	272
318	Eli Lilly	Basaglar	Insulin Glargine	Diabetes	USD	Millions	86	11	86	11	75	682
319	Eli Lilly	Other Endocrinology			USD	Millions	43	37	43	37	6	16
320	Eli Lilly	Total Endocrinology			USD	Millions	8,083	7,037	8,083	7,037	1,046	15
321	Eli Lilly	Alimta	Pemetrexed	Oncology	USD	Millions	2,283	2,493	2,283	2,493	-210	-8
322	Eli Lilly	Gemzar	Gemcitabine	Oncology	USD	Millions	111	147	111	147	-36	-24
323	Eli Lilly	Cyramza	Ramucirumab	Oncology	USD	Millions	614	384	614	384	230	60
324	Eli Lilly	Portrazza	Necitumumab	Oncology	USD	Millions	15	Not Reported	15	Not Reported	15	New Launch
325	Eli Lilly	Lartruvo	Olaratumab	Oncology	USD	Millions	12	Not Reported	12	Not Reported	12	New Launch
326	Eli Lilly	Erbitux	Cetuximab	Oncology	USD	Millions	687	485	687	485	202	42
327	Eli Lilly	Other Oncology			USD	Millions	-0.2	1	-0.2	1	-1	-120
328	Eli Lilly	Total Oncology			USD	Millions	3,722	3,510	3,722	3,510	212	6
329	Eli Lilly	Cialis	Tadalafil	Sexual Health	USD	Millions	2,472	2,311	2,472	2,311	161	7
330	Eli Lilly	Reopro	Abciximab	Cardiovascular Diseases	USD	Millions	87	98	87	98	-11	-11
331	Eli Lilly	Effient	Prasugrel	Cardiovascular Diseases	USD	Millions	535	523	535	523	12	2
332	Eli Lilly	Adcirca	Tadalafil	Cardiovascular Diseases	USD	Millions	82	76	82	76	6	8
333	Eli Lilly	Other Cardiovascular			USD	Millions	51	61	51	61	-10	-16
334	Eli Lilly	Total Cardiovascular			USD	Millions	3,225	3,068	3,225	3,068	157	5
335	Eli Lilly	Vancocin	Vancomycin Hydrochloride	Anti-Bacterial	USD	Millions	85	90	85	90	-5	-6
336	Eli Lilly	Others			USD	Millions	116	138	116	138	-22	-16
337	Eli Lilly	Other Pharmaceutical			USD	Millions	201	228	201	228	-27	-12
338	Eli Lilly	Total Pharmaceuticals			USD	Millions	18,064	16,778	18,064	16,778	1,286	8
339	Eli Lilly	Food And Other			USD	Millions	2,189	2,262	2,189	2,262	-73	-3
340	Eli Lilly	Companion			USD	Millions	970	919	970	919	51	6
341	Eli Lilly	Total Animal Health			USD	Millions	3,158	3,181	3,158	3,181	-23	-1
342	Eli Lilly	Total Revenues			USD	Millions	21,222	19,959	21,223	19,959	1,264	6
343	Fresenius Kabi	Fresenius Medical Care			USD	Millions	16,181	15,086	16,181	15,086	1,095	7
344	Fresenius Kabi	Fresenius Kabi			USD	Millions	6,007	5,950	6,007	5,950	57	1
345	Fresenius Kabi	Fresenius Helios			USD	Millions	5,843	5,578	5,843	5,578	265	5
346	Fresenius Kabi	Fresenius Vamed			USD	Millions	1,160	1,118	1,160	1,118	42	4
347	Fresenius Kabi	Total Revenues			USD	Millions	29,083	27,626	29,083	27,626	1,457	5
348	Gilead	Sovaldi	Sofosbuvir	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	4,001	5,276	4,001	5,276	-1,275	-24
349	Gilead	Atripla	Efavirenz, Emtricitabine, And Tenofovir Disoproxil Fumarate	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	2,605	3,134	2,605	3,134	-529	-17
350	Gilead	Truvada	Emtricitabine, And Tenofovir Disoproxil Fumarate	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	3,566	3,459	3,566	3,459	107	3
351	Gilead	Harvoni	Ledipasvir And Sofosbuvir	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	9,081	13,864	9,081	13,864	-4,783	-34
352	Gilead	Complera/Eviplera	Rilpivirine, Emtricitabine, And Tenofovir Disoproxil Fumarate	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	1,457	1,427	1,457	1,427	30	2
353	Gilead	Stribild	Cobicistat, Elvitegravir, Emtricitabine And Tenofovir Disoproxil Fumarate	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	1,914	1,825	1,914	1,825	89	5
354	Gilead	Viread	Tenofovir Disoproxil Fumarate	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	1,186	1,108	1,186	1,108	78	7
355	Gilead	Epclusa	Sofosbuvir And Velpatasvir	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	1,752	Not Reported	1,752	Not Reported	1,752	New Launch
356	Gilead	Odefsey	Emtricitabine, Rilpivirine, And Tenofovir Alafenamide	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	329	Not Reported	329	Not Reported	329	New Launch
357	Gilead	Descovy	Emtricitabine And Tenofovir Alafenamide	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	298	Not Reported	298	Not Reported	298	New Launch
358	Gilead	Genvoya	Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Alafenamide	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	1,484	45	1,484	45	1,439	3,198
359	Gilead	Other Antiviral			USD	Millions	72	69	72	69	3	4
360	Gilead	Total Antiviral Products			USD	Millions	27,745	30,207	27,745	30,207	-2,462	-8
361	Gilead	Letairis	Ambrisentan	Cardiovascular Diseases	USD	Millions	819	700	819	700	119	17
362	Gilead	Ranexa	Ranolazine	Cardiovascular Diseases	USD	Millions	677	588	677	588	89	15
363	Gilead	Ambisome	Amphotericin B	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	356	350	356	350	6	2
364	Gilead	Zydelig	Idelalisib	Oncology	USD	Millions	168	132	168	132	36	27
365	Gilead	Others			USD	Millions	188	174	188	174	14	8
366	Gilead	Total Other Products			USD	Millions	2,208	1,944	2,208	1,944	264	14
367	Gilead	Total Product Sales			USD	Millions	29,953	32,151	29,953	32,151	-2,198	-7
368	Gilead	Royalty Contract And Other Revenues			USD	Millions	437	488	437	488	-51	-10
369	Gilead	Total Revenues			USD	Millions	30,390	32,639	30,390	32,639	-2,249	-7
370	GlaxoSmithKline Plc	Anoro Ellipta	Umeclidinium And Vilanterol	Respiratory Disorders	GBP	Millions	201	79	249	98	151	154
371	GlaxoSmithKline Plc	Avamys/Veramyst	Fluticasone Furoate	Respiratory Disorders	GBP	Millions	277	229	343	284	60	21
372	GlaxoSmithKline Plc	Flixotide/Flovent	Fluticasone Propionate	Respiratory Disorders	GBP	Millions	637	623	790	773	17	2
373	GlaxoSmithKline Plc	Relvar/Breo Ellipta	Fluticasone Furoate	Respiratory Disorders	GBP	Millions	620	257	769	319	450	141
374	GlaxoSmithKline Plc	Seretide/Advair	Salmeterol	Respiratory Disorders	GBP	Millions	3,485	3,681	4,321	4,564	-243	-5
375	GlaxoSmithKline Plc	Incruse Ellipta	Umeclidinium	Respiratory Disorders	GBP	Millions	114	14	141	17	124	729
376	GlaxoSmithKline Plc	Nucala	Mepolizumab	Respiratory Disorders	GBP	Millions	102	1	126	2	124	6,200
377	GlaxoSmithKline Plc	Arnuity Ellipta	Fluticasone Furoate	Respiratory Disorders	GBP	Millions	15	3	19	4	15	375
378	GlaxoSmithKline Plc	Ventolin	Albuterol	Respiratory Disorders	GBP	Millions	785	620	973	769	205	27
379	GlaxoSmithKline Plc	Others			GBP	Millions	274	252	340	312	27	9
380	GlaxoSmithKline Plc	Total Respiratory			GBP	Millions	6,510	5,741	8,072	7,119	954	13
381	GlaxoSmithKline Plc	Avodart	Dutasteride	Urology	GBP	Millions	635	657	787	815	-27	-3
382	GlaxoSmithKline Plc	Eperzan/Tanzeum	Albiglutide	Diabetes	GBP	Millions	121	41	150	50	100	200
383	GlaxoSmithKline Plc	Other			GBP	Millions	104	201	129	249	-120	-48
384	GlaxoSmithKline Plc	Total Cardiovascular, Metabolic And Urology			GBP	Millions	860	858	1,066	1,064	2	0
385	GlaxoSmithKline Plc	Benlysta	Belimumab	Rare Diseases	GBP	Millions	306	230	379	285	94	33
386	GlaxoSmithKline Plc	Others			GBP	Millions	34	33	42	41	1	3
387	GlaxoSmithKline Plc	Total Immuno-Inflammation			GBP	Millions	340	263	422	326	95	29
388	GlaxoSmithKline Plc	Dermatology			GBP	Millions	393	412	487	511	-24	-5
389	GlaxoSmithKline Plc	Augmentin	Amoxicillin And Clavulanate Potassium	Anti-Bacterial	GBP	Millions	563	528	698	655	43	7
390	GlaxoSmithKline Plc	Other Anti-Bacterials			GBP	Millions	169	184	210	228	-19	-8
391	GlaxoSmithKline Plc	Rare Diseases			GBP	Millions	423	371	525	460	64	14
392	GlaxoSmithKline Plc	Oncology			GBP	Millions	161	255	200	316	-117	-37
393	GlaxoSmithKline Plc	Others			GBP	Millions	588	704	729	873	-144	-16
394	GlaxoSmithKline Plc	Total Other Pharmaceuticals			GBP	Millions	2,297	2,445	2,848	3,043	-195	-6
395	GlaxoSmithKline Plc	Bexsero	Meningococcal vaccine	Vaccines	GBP	Millions	390	115	484	143	341	239
396	GlaxoSmithKline Plc	Boostrix	Diphtheria, Tetanus Acellular, and Pertussis	Vaccines	GBP	Millions	470	358	583	444	139	31
397	GlaxoSmithKline Plc	Cervarix	Human Papillomavirus Bivalent	Vaccines	GBP	Millions	81	88	100	109	-9	-8
398	GlaxoSmithKline Plc	Fluarix, Flulaval	Influenza vaccine	Vaccines	GBP	Millions	414	268	513	332	181	54
399	GlaxoSmithKline Plc	Hepatitis	Vaccine	Vaccines	GBP	Millions	602	540	746	670	77	11
400	GlaxoSmithKline Plc	Infanrix, Pediarix	Diphtheria, Tetanus Acellular, and Pertussis	Vaccines	GBP	Millions	769	733	954	909	45	5
401	GlaxoSmithKline Plc	Menveo	Meningococcal vaccine	Vaccines	GBP	Millions	202	160	250	198	52	26
402	GlaxoSmithKline Plc	Rabipur/Rabivert	Vaccine	Vaccines	GBP	Millions	Not Reported	61	Not Reported	76	-76	-100
403	GlaxoSmithKline Plc	Rotarix	Vaccine	Vaccines	GBP	Millions	469	417	582	517	64	12
404	GlaxoSmithKline Plc	Priorix, Priorix Tetra, Varilrix	Vaccine	Vaccines	GBP	Millions	300	260	372	320	52	16
405	GlaxoSmithKline Plc	Synflorix	Vaccine	Vaccines	GBP	Millions	504	381	625	472	153	32
406	GlaxoSmithKline Plc	Others			GBP	Millions	391	536	485	665	-180	-27
407	GlaxoSmithKline Plc	Total Vaccines			GBP	Millions	4,592	3,656	5,694	4,535	1,159	26
408	GlaxoSmithKline Plc	Combivir	Lamivudine And Zidovudine	Infectious Diseases (HIV, Hepatitis etc.)	GBP	Millions	23	34	29	42	-14	-32
409	GlaxoSmithKline Plc	Epzicom/Kivexa	Abacavir And Lamivudine	Infectious Diseases (HIV, Hepatitis etc.)	GBP	Millions	568	698	704	866	-161	-19
410	GlaxoSmithKline Plc	Lexiva/Agenerase	Fosamprenavir	Infectious Diseases (HIV, Hepatitis etc.)	GBP	Millions	51	65	63	81	-17	-22
411	GlaxoSmithKline Plc	Selzentry	Maraviroc	Infectious Diseases (HIV, Hepatitis etc.)	GBP	Millions	125	124	155	154	1	1
412	GlaxoSmithKline Plc	Tivicay	Dolutegravir	Infectious Diseases (HIV, Hepatitis etc.)	GBP	Millions	953	588	1,182	729	453	62
413	GlaxoSmithKline Plc	Triumeq	Abacavir, Dolutegravir And Lamivudine	Infectious Diseases (HIV, Hepatitis etc.)	GBP	Millions	1,735	730	2,151	905	1,246	138
414	GlaxoSmithKline Plc	Trizivir	Abacavir, Lamivudine, And Zidovudine	Infectious Diseases (HIV, Hepatitis etc.)	GBP	Millions	16	26	20	32	-12	-38
415	GlaxoSmithKline Plc	Others			GBP	Millions	85	57	105	71	35	49
416	GlaxoSmithKline Plc	Total HIV			GBP	Millions	3,556	2,322	4,409	2,879	1,530	53
417	GlaxoSmithKline Plc	Coreg	Carvedilol	Cardiovascular Diseases	GBP	Millions	131	123	162	153	10	7
418	GlaxoSmithKline Plc	Hepsera	Adefovir	Infectious Diseases (HIV, Hepatitis etc.)	GBP	Millions	58	63	72	78	-6	-8
419	GlaxoSmithKline Plc	Imigran/Imitrex	Sumatriptan Succinate	Neurological/Mental Disorders	GBP	Millions	177	160	219	198	21	11
420	GlaxoSmithKline Plc	Lamictal	Lamotrigine	Neurological/Mental Disorders	GBP	Millions	614	531	761	658	103	16
421	GlaxoSmithKline Plc	Lovaza	Omega-3 Polyunsaturated Fatty Acids	Cardiovascular Diseases	GBP	Millions	43	93	53	115	-62	-54
422	GlaxoSmithKline Plc	Requip	Ropinirole	Neurological/Mental Disorders	GBP	Millions	116	93	144	115	29	25
423	GlaxoSmithKline Plc	Serevent	Salmeterol	Respiratory Disorders	GBP	Millions	96	93	119	115	4	3
424	GlaxoSmithKline Plc	Seroxat/ Paxil	Paroxetine Hydrochloride Hemihydrate	Neurological/Mental Disorders	GBP	Millions	206	165	255	205	51	25
425	GlaxoSmithKline Plc	Valtrex	Valacyclovir	Infectious Diseases (HIV, Hepatitis etc.)	GBP	Millions	118	165	146	205	-58	-28
426	GlaxoSmithKline Plc	Zeffix	Lamivudine	Infectious Diseases (HIV, Hepatitis etc.)	GBP	Millions	111	134	138	166	-29	-17
427	GlaxoSmithKline Plc	Others			GBP	Millions	871	908	1,080	1,126	-46	-4
428	GlaxoSmithKline Plc	Established Products			GBP	Millions	2,541	2,528	3,151	3,135	16	1
429	GlaxoSmithKline Plc	Total Pharmaceuticals			GBP	Millions	16,104	14,157	19,969	17,566	2,403	14
430	GlaxoSmithKline Plc	Consumer Healthcare Turnover			GBP	Millions	7,193	6,038	8,919	7,475	1,445	19
431	GlaxoSmithKline Plc	Total Sales			GBP	Millions	27,889	23,923	34,582	29,575	5,007	17
432	Ipsen	Decapeptyl	Triptorelin	Hormonal Disorders	Euro	Millions	340	334	360	354	6	2
433	Ipsen	Somatuline	Lanreotide	Oncology	Euro	Millions	538	402	570	426	144	34
434	Ipsen	Cabometyx	Cabozantinib	Oncology	Euro	Millions	7	Not Reported	7	Not Reported	7	New Launch
435	Ipsen	Other Oncology			Euro	Millions	20	17	21	18	3	18
436	Ipsen	Oncology			Euro	Millions	905	753	959	798	161	20
437	Ipsen	Dysport	Abobotulinumtoxin A	Lower Limb Spasticity	Euro	Millions	285	280	302	297	5	2
438	Ipsen	Neuroscience			Euro	Millions	285	280	302	297	5	2
439	Ipsen	Nutropin	Somatropin (Rdna Origin)	Hormonal Disorders	Euro	Millions	58	60	61	64	-2	-3
440	Ipsen	Increlex	Mecasermin	Metabolic Disorders	Euro	Millions	24	20	25	21	4	20
441	Ipsen	Endocrinology			Euro	Millions	81	80	86	85	1	1
442	Ipsen	Total Specialty Care			Euro	Millions	1,273	1,114	1,349	1,181	169	14
443	Ipsen	Smecta	Dioctahedral Smectite	Gastrointestinal Disorders	Euro	Millions	111	115	118	122	-4	-3
444	Ipsen	Fortrans	Macrogol	Gastrointestinal Disorders	Euro	Millions	23	24	24	25	-1	-4
445	Ipsen	Etiasa	Mesalazine	Gastrointestinal Disorders	Euro	Millions	29	26	31	28	3	12
446	Ipsen	Forlax	Macrogol	Gastrointestinal Disorders	Euro	Millions	39	40	41	42	-1	-3
447	Ipsen	Gastroenterology			Euro	Millions	219	227	232	241	-8	-4
448	Ipsen	Tanakan	Ginkgo Biloba Extract	Neurological/Mental Disorders	Euro	Millions	44	52	47	55	-8	-15
449	Ipsen	Cognitive Disorders			Euro	Millions	44	52	47	55	-8	-15
450	Ipsen	Other Primary Care			Euro	Millions	24	26	25	28	-2	-8
451	Ipsen	Drug-Related Sales			Euro	Millions	26	24	28	25	2	8
452	Ipsen	Total Primary Care			Euro	Millions	312	330	331	350	-19	-5
453	Ipsen	Total Sales			Euro	Millions	1,585	1,444	1,680	1,531	149	10
454	Johnson & Johnson	Remicade	Infliximab	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	6,966	6,561	6,966	6,561	405	6
455	Johnson & Johnson	Simponi/Simponi Aria	Golimumab	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	1,745	1,328	1,745	1,328	417	31
456	Johnson & Johnson	Stelara	Ustekinumab	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	3,232	2,474	3,232	2,474	758	31
457	Johnson & Johnson	Other Products			USD	Millions	25	39	25	39	-14	-36
458	Johnson & Johnson	Total Immunology			USD	Millions	11,968	10,402	11,968	10,402	1,566	15
459	Johnson & Johnson	Edurant	Rilpivirine	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	573	410	573	410	163	40
460	Johnson & Johnson	Olysio/Sovriad	Simeprevir	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	106	621	106	621	-515	-83
461	Johnson & Johnson	Prezista	Darunavir	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	1,851	1,810	1,851	1,810	41	2
462	Johnson & Johnson	Other Products			USD	Millions	678	815	678	815	-137	-17
463	Johnson & Johnson	Total Infectious Diseases			USD	Millions	3,208	3,656	3,208	3,656	-448	-12
464	Johnson & Johnson	Concerta	Methylphenidate	Neurological/Mental Disorders	USD	Millions	863	821	863	821	42	5
465	Johnson & Johnson	Invega	Paliperidone	Neurological/Mental Disorders	USD	Millions	311	573	311	573	-262	-46
466	Johnson & Johnson	Invega Sustenna/Xeplion	Paliperidone Palmitate	Neurological/Mental Disorders	USD	Millions	2,214	1,830	2,214	1,830	384	21
467	Johnson & Johnson	Risperdal Consta	Risperidone	Neurological/Mental Disorders	USD	Millions	893	970	893	970	-77	-8
468	Johnson & Johnson	Other Products			USD	Millions	1,804	2,065	1,804	2,065	-261	-13
469	Johnson & Johnson	Total Neuroscience			USD	Millions	6,085	6,259	6,085	6,259	-174	-3
470	Johnson & Johnson	Darzalex	Daratumumab	Oncology	USD	Millions	572	20	572	20	552	2,760
471	Johnson & Johnson	Imbruvica	Ibrutinib	Oncology	USD	Millions	1,251	689	1,251	689	562	82
472	Johnson & Johnson	Velcade	Bortezomib	Oncology	USD	Millions	1,224	1,333	1,224	1,333	-109	-8
473	Johnson & Johnson	Zytiga	Abiraterone Acetate	Oncology	USD	Millions	2,260	2,231	2,260	2,231	29	1
474	Johnson & Johnson	Other Products			USD	Millions	500	442	500	442	58	13
475	Johnson & Johnson	Total Oncology			USD	Millions	5,807	4,695	5,807	4,695	1,112	24
476	Johnson & Johnson	Invokana/Invokamet	Canagliflozin/ Canagliflozin And Metformin Hcl	Diabetes	USD	Millions	1,407	1,308	1,407	1,308	99	8
477	Johnson & Johnson	Procrit/Eprex	Epoetin Alfa	Blood Disorders	USD	Millions	1,105	1,068	1,105	1,068	37	3
478	Johnson & Johnson	Xarelto	Rivaroxaban	Cardiovascular Diseases	USD	Millions	2,288	1,868	2,288	1,868	420	22
479	Johnson & Johnson	Other Products			USD	Millions	1,596	2,174	1,596	2,174	-578	-27
480	Johnson & Johnson	Total Other Prescription Products			USD	Millions	6,396	6,418	6,396	6,418	-22	0
481	Johnson & Johnson	Total Pharmaceuticals			USD	Millions	33,464	31,430	33,464	31,430	2,034	6
482	Johnson & Johnson	Consumer Health Care			USD	Millions	13,307	13,507	13,307	13,507	-200	-1
483	Johnson & Johnson	Medical Devices			USD	Millions	25,119	25,137	25,119	25,137	-18	0
484	Johnson & Johnson	Total All Divisions			USD	Millions	71,890	70,074	71,890	70,074	1,816	3
485	Mallinckrodt Plc	Acthar	Corticotropin	Autoimmune Disorders	USD	Millions	1,160	1,037	1,160	1,037	123	12
486	Mallinckrodt Plc	Inomax	Nitric Oxide	Respiratory Disorders	USD	Millions	474	185	474	185	289	156
487	Mallinckrodt Plc	Ofirmev	Acetaminophen	Anti-Inflammatory	USD	Millions	284	263	284	263	21	8
488	Mallinckrodt Plc	Therakos Immunotherapy			USD	Millions	208	Not Reported	208	Not Reported	208	Not Reported
489	Mallinckrodt Plc	Hemostasis Products			USD	Millions	43	Not Reported	43	Not Reported	43	Not Reported
490	Mallinckrodt Plc	Others			USD	Millions	132	137	132	137	-5	-4
491	Mallinckrodt Plc	Specialty Brands			USD	Millions	2,301	1,623	2,301	1,623	678	42
492	Mallinckrodt Plc	Hydrocodone (API) And Hydrocodone-Containing Tablets	Hydrocodone Bitartrate	Anti-Inflammatory	USD	Millions	147	167	147	167	-20	-12
493	Mallinckrodt Plc	Oxycodone (Api) And Oxycodone-Containing Tablets	Oxycodone	Anti-Inflammatory	USD	Millions	126	155	126	155	-29	-19
494	Mallinckrodt Plc	Methylphenidate Er	Methylphenidate Hydrochloride	Neurological/Mental Disorders	USD	Millions	104	137	104	137	-33	-24
495	Mallinckrodt Plc	Other Controlled Substances			USD	Millions	468	572	468	572	-104	-18
496	Mallinckrodt Plc	Others			USD	Millions	181	221	181	221	-40	-18
497	Mallinckrodt Plc	Specialty Generics			USD	Millions	1,025	1,252	1,025	1,252	-227	-18
498	Mallinckrodt Plc	Others			USD	Millions	55	49	55	49	6	12
499	Mallinckrodt Plc	Total Sales			USD	Millions	3,381	2,923	3,381	2,923	458	16
500	Merck & Co.	Zetia	Ezetimibe	Cardiovascular Diseases	USD	Millions	2,560	2,526	2,560	2,526	34	1
501	Merck & Co.	Vytorin	Ezetimibe And Simvastatin	Cardiovascular Diseases	USD	Millions	1,141	1,250	1,141	1,250	-109	-9
502	Merck & Co.	Total Cardiovascular			USD	Millions	3,701	3,776	3,701	3,776	-75	-2
503	Merck & Co.	Januvia	Sitagliptin	Diabetes	USD	Millions	3,908	3,864	3,908	3,864	44	1
504	Merck & Co.	Janumet	Metformin And Sitagliptin	Diabetes	USD	Millions	2,201	2,151	2,201	2,151	50	2
505	Merck & Co.	Total Diabetes			USD	Millions	6,109	6,015	6,109	6,015	94	2
506	Merck & Co.	Nuvaring	Ethinyl Estradiol And Etonogestrel	Sexual Health	USD	Millions	777	731	777	731	46	6
507	Merck & Co.	Implanon/Nexplanon	Etonogestrel	Sexual Health	USD	Millions	606	588	606	588	18	3
508	Merck & Co.	Dulera	Formoterol And Mometasone	Respiratory Disorders	USD	Millions	436	536	436	536	-100	-19
509	Merck & Co.	Follistim Aq	Follicle Stimulating Hormone	Sexual Health	USD	Millions	355	383	355	383	-28	-7
510	Merck & Co.	Total General Medicine & Women'S Health			USD	Millions	2,174	2,238	2,174	2,238	-64	-3
511	Merck & Co.	Zepatier	Elbasvir And Grazoprevir	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	555	Not Reported	555	Not Reported	555	New Launch
512	Merck & Co.	Pegintron	Peginterferon Alfa-2B	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	Not Reported	182	Not Reported	182	-182	-100
513	Merck & Co.	Total Hepatitis			USD	Millions	555	182	555	182	373	205
514	Merck & Co.	Isentress	Raltegravir	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	1,387	1,511	1,387	1,511	-124	-8
515	Merck & Co.	Total HIV			USD	Millions	1,387	1,511	1,387	1,511	-124	-8
516	Merck & Co.	Cubicin	Daptomycin	Anti-Bacterial	USD	Millions	1,087	1,127	1,087	1,127	-40	-4
517	Merck & Co.	Cancidas	Caspofungin	Anti-Fungal	USD	Millions	558	572	558	572	-14	-2
518	Merck & Co.	Invanz	Ertapenem	Anti-Bacterial	USD	Millions	561	569	561	569	-8	-1
519	Merck & Co.	Noxafil	Posaconazole	Anti-Fungal	USD	Millions	595	487	595	487	108	22
520	Merck & Co.	Bridion	Sugammadex	Neurological/Mental Disorders	USD	Millions	482	353	482	353	129	37
521	Merck & Co.	Primaxin	Imipenem And Cilastatin	Anti-Bacterial	USD	Millions	297	313	297	313	-16	-5
522	Merck & Co.	Total Hospital Acute Care			USD	Millions	3,580	3,421	3,580	3,421	159	5
523	Merck & Co.	Remicade	Infliximab	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	1,268	1,794	1,268	1,794	-526	-29
524	Merck & Co.	Simponi	Golimumab	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	766	690	766	690	76	11
525	Merck & Co.	Total Immunology			USD	Millions	2,034	2,484	2,034	2,484	-450	-18
526	Merck & Co.	Keytruda	Pembrolizumab	Oncology	USD	Millions	1,402	566	1,402	566	836	148
527	Merck & Co.	Emend	Aprepitant	Oncology	USD	Millions	549	535	549	535	14	3
528	Merck & Co.	Temodar	Temozolomide	Oncology	USD	Millions	283	313	283	313	-30	-10
529	Merck & Co.	Total Oncology			USD	Millions	2,234	1,414	2,234	1,414	820	58
530	Merck & Co.	Singulair	Montelukast Sodium	Respiratory Disorders	USD	Millions	915	931	915	931	-16	-2
531	Merck & Co.	Nasonex	Mometasone Furoate	Respiratory Disorders	USD	Millions	537	858	537	858	-321	-37
532	Merck & Co.	Clarinex	Desloratadine	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	Not Reported	187	Not Reported	187	-187	-100
533	Merck & Co.	Total Respiratory			USD	Millions	1,452	1,976	1,452	1,976	-524	-27
534	Merck & Co.	Cozaar/Hyzaar	Losartan And Hydrochlorothiazide	Cardiovascular Diseases	USD	Millions	511	667	511	667	-156	-23
535	Merck & Co.	Arcoxia	Etoricoxib	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	450	471	450	471	-21	-4
536	Merck & Co.	Fosamax	Alendronate	Bone Health	USD	Millions	284	359	284	359	-75	-21
537	Merck & Co.	Zocor	Simvastatin	Cardiovascular Diseases	USD	Millions	186	217	186	217	-31	-14
538	Merck & Co.	Propecia	Finasteride	Dermatology	USD	Millions	Not Reported	183	Not Reported	183	-183	-100
539	Merck & Co.	Total Other			USD	Millions	1,431	1,714	1,431	1,714	-283	-17
540	Merck & Co.	Gardasil/Gardasil 9	Hpv Quadrivalent Vaccine	Oncology	USD	Millions	2,173	1,908	2,173	1,908	265	14
541	Merck & Co.	Proquad, M-M-R II And Varivax	Measles, Mumps, Rubella And Varicella Virus Vaccine Live	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	1,640	1,504	1,640	1,504	136	9
542	Merck & Co.	Zostavax	Zoster Vaccine Live	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	685	749	685	749	-64	-9
543	Merck & Co.	Rotateq	Rotavirus Vaccine	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	652	610	652	610	42	7
544	Merck & Co.	Pneumovax 23	Pneumococcal Vaccine Polyvalent	Infectious Diseases (HIV, Hepatitis etc.)	USD	Millions	641	542	641	542	99	18
545	Merck & Co.	Total Vaccines			USD	Millions	5,791	5,313	5,791	5,313	478	9
546	Merck & Co.	Other Pharmaceutical			USD	Millions	4,703	5,107	4,703	5,107	-404	-8
547	Merck & Co.	Animal Health			USD	Millions	3,478	3,331	3,478	3,331	147	4
548	Merck & Co.	Consumer Care			USD	Millions	Not Reported	3	Not Reported	3	-3	-100
549	Merck & Co.	Other Revenues			USD	Millions	1,178	1,389	1,178	1,389	-211	-15
550	Merck & Co.	Total Pharmaceuticals			USD	Millions	35,151	34,782	35,151	34,782	369	1
551	Merck & Co.	Total Sales			USD	Millions	39,807	39,498	39,807	39,498	309	1
552	Novartis	Gleevec/Glivec	Imatinib	Oncology	USD	Millions	3,323	4,658	3,323	4,658	-1,335	-29
553	Novartis	Tasigna	Nilotinib	Oncology	USD	Millions	1,739	1,632	1,739	1,632	107	7
554	Novartis	Subtotal Bcr-Abl Franchise			USD	Millions	5,062	6,290	5,062	6,290	-1,228	-20
555	Novartis	Sandostatin	Octreotide	Oncology	USD	Millions	1,646	1,630	1,646	1,630	16	1
556	Novartis	Afinitor/Votubia	Everolimus	Oncology	USD	Millions	1,516	1,607	1,516	1,607	-91	-6
557	Novartis	Exjade	Deferasirox	Oncology	USD	Millions	956	917	956	917	39	4
558	Novartis	Votrient	Pazopanib	Oncology	USD	Millions	729	565	729	565	164	29
559	Novartis	Tafinlar/Mekinist	Dabrafenib/ Trametinib	Oncology	USD	Millions	672	453	672	453	219	48
560	Novartis	Jakavi	Ruxolitinib	Oncology	USD	Millions	581	410	581	410	171	42
561	Novartis	Revolade/Promacta	Eltrombopag Olamine/ Eltrombopag	Oncology	USD	Millions	635	402	635	402	233	58
562	Novartis	Zykadia	Ceritinib	Oncology	USD	Millions	91	79	91	79	12	15
563	Novartis	Others			USD	Millions	902	951	902	951	-49	-5
564	Novartis	Total Oncology			USD	Millions	12,790	13,304	12,790	13,304	-514	-4
565	Novartis	Gilenya	Fingolimod	Neurological/Mental Disorders	USD	Millions	3,109	2,776	3,109	2,776	333	12
566	Novartis	Exelon/Exelon Patch	Rivastigmine	Neurological/Mental Disorders	USD	Millions	444	728	444	728	-284	-39
567	Novartis	Others			USD	Millions	124	141	124	141	-17	-12
568	Novartis	Total Neuroscience			USD	Millions	3,677	3,645	3,677	3,645	32	1
569	Novartis	Lucentis	Ranibizumab	Ophthalmology	USD	Millions	1,835	2,060	1,835	2,060	-225	-11
570	Novartis	Travoprost Group	Travoprost	Ophthalmology	USD	Millions	619	631	619	631	-12	-2
571	Novartis	Topical Olopatadine Group	Olopatadine	Ophthalmology	USD	Millions	335	457	335	457	-122	-27
572	Novartis	Systane Group	Propylene Glycol	Ophthalmology	USD	Millions	377	380	377	380	-3	-1
573	Novartis	Other			USD	Millions	2,297	2,395	2,297	2,395	-98	-4
574	Novartis	Total Ophthalmology			USD	Millions	5,463	5,923	5,463	5,923	-460	-8
575	Novartis	Neoral/Sandimmun(E)	Cyclosporine	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	515	570	515	570	-55	-10
576	Novartis	Myfortic	Mycophenolic Acid	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	383	441	383	441	-58	-13
577	Novartis	Zortress/Certican	Everolimus	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	398	335	398	335	63	19
578	Novartis	Cosentyx	Secukinumab	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	1,128	261	1,128	261	867	332
579	Novartis	Ilaris	Canakinumab	Rare Diseases	USD	Millions	283	236	283	236	47	20
580	Novartis	Others			USD	Millions	172	160	172	160	12	8
581	Novartis	Subtotal Immunology And Dermatology Excluding Everolimus Stent Drug			USD	Millions	2,879	2,003	2,879	2,003	876	44
582	Novartis	Everolimus Stent Drug	Everolimus	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	136	134	136	134	2	1
583	Novartis	Total Immunology And Dermatology			USD	Millions	3,015	2,137	3,015	2,137	878	41
584	Novartis	Ultibro Breezhaler	Indacaterol And Glycopyrronium Bromide	Respiratory Disorders	USD	Millions	363	260	363	260	103	40
585	Novartis	Onbrez Breezhaler/Arcapta Neohaler	Indacaterol Maleate	Respiratory Disorders	USD	Millions	143	166	143	166	-23	-14
586	Novartis	Seebri Breezhaler	Glycopyrronium Bromide	Respiratory Disorders	USD	Millions	149	150	149	150	-1	-1
587	Novartis	Subtotal Copd1 Portfolio			USD	Millions	655	576	655	576	79	14
588	Novartis	Xolair	Omalizumab	Respiratory Disorders	USD	Millions	835	755	835	755	80	11
589	Novartis	Others			USD	Millions	31	37	31	37	-6	-16
590	Novartis	Total Respiratory			USD	Millions	1,521	1,368	1,521	1,368	153	11
591	Novartis	Galvus	Vildagliptin	Diabetes	USD	Millions	1,193	1,140	1,193	1,140	53	5
592	Novartis	Entresto	Sacubitril And Valsartan	Cardiovascular Diseases	USD	Millions	170	21	170	21	149	710
593	Novartis	Others			USD	Millions	14	Not Reported	14	Not Reported	14	Not Reported
594	Novartis	Total Cardio-Metabolic			USD	Millions	1,377	1,161	1,377	1,161	216	19
595	Novartis	Diovan	Hydrochlorothiazide And Valsartan	Cardiovascular Diseases	USD	Millions	1,073	1,284	1,073	1,284	-211	-16
596	Novartis	Exforge	Amlodipine And Valsartan	Cardiovascular Diseases	USD	Millions	926	1,047	926	1,047	-121	-12
597	Novartis	Voltaren (Excluding Other Divisions)	Diclofenac	Anti-Inflammatory	USD	Millions	525	558	525	558	-33	-6
598	Novartis	Ritalin/Focalin	Dexmethylphenidate	Neurological/Mental Disorders	USD	Millions	282	365	282	365	-83	-23
599	Novartis	Others			USD	Millions	1,913	2,553	1,913	2,553	-640	-25
600	Novartis	Total Established Medicines			USD	Millions	4,719	5,807	4,719	5,807	-1,088	-19
601	Novartis	Total Division Net Sales			USD	Millions	32,562	33,345	32,562	33,345	-783	-2
602	Novartis	of Which Growth Products			USD	Millions	14,805	12,210	14,805	12,210	2,595	21
603	Novartis	of Which Rest of Portfolio			USD	Millions	17,757	21,135	17,757	21,135	-3,378	-16
604	Novartis	Net Sales By Alcon			USD	Millions	5,812	5,999	5,812	5,999	-187	-3
605	Novartis	Net Sales By Sandoz			USD	Millions	10,144	10,070	10,144	10,070	74	1
606	Novartis	Total Sales By Continuing Operation			USD	Millions	48,518	49,414	48,518	49,414	-896	-2
607	Novartis	Total Sales By Discontinuing Operation			USD	Millions	Not Reported	601	Not Reported	601	-601	-100
608	Novartis	Total Group Net Sales			USD	Millions	48,518	50,015	48,518	50,015	-1,497	-3
609	Novo Nordisk	New-Generation Insulin	Insulin	Diabetes	DKK	Millions	4,459	1,438	624	201	423	210
610	Novo Nordisk	Novorapid/Novolog	Insulin Aspart	Diabetes	DKK	Millions	19,945	20,720	2,792	2,901	-109	-4
611	Novo Nordisk	Novomix/Novolog Mix	Biphasic Insulin Aspart	Diabetes	DKK	Millions	10,482	11,144	1,467	1,560	-93	-6
612	Novo Nordisk	Levemir	Insulin Detemirn	Diabetes	DKK	Millions	17,083	18,300	2,392	2,562	-170	-7
613	Novo Nordisk	Total Modern Insulins	Insulin	Diabetes	DKK	Millions	47,510	50,164	6,651	7,023	-372	-5
614	Novo Nordisk	Human Insulins	Insulin	Diabetes	DKK	Millions	11,090	11,231	1,553	1,572	-20	-1
615	Novo Nordisk	Victoza	Liraglutide	Diabetes	DKK	Millions	20,046	18,027	2,806	2,524	283	11
616	Novo Nordisk	Other Diabetes And Obesity Care			DKK	Millions	5,844	4,730	818	662	156	24
617	Novo Nordisk	of Which Saxenda	Liraglutide	Weight Loss and Obesity	DKK	Millions	1,577	460	221	64	156	243
618	Novo Nordisk	Total Diabetes Care			DKK	Millions	88,949	85,590	12,453	11,983	470	4
619	Novo Nordisk	Haemophilia	Recombinant Human Coagulation Factor Viia	Blood Disorders	DKK	Millions	10,472	10,647	1,466	1,491	-25	-2
620	Novo Nordisk	Norditropin	Somatropin	Hormonal Disorders	DKK	Millions	8,770	7,820	1,228	1,095	133	12
621	Novo Nordisk	Other Biopharmaceuticals			DKK	Millions	3,589	3,870	502	542	-39	-7
622	Novo Nordisk	Total Biopharmaceuticals			DKK	Millions	22,831	22,337	3,196	3,127	69	2
623	Novo Nordisk	Total Sales			DKK	Millions	111,780	107,927	15,649	15,110	539	4
624	Otsuka	Abilify	Aripiprazole	Neurological/Mental Disorders	Yen	Millions	95,000	348,000	855	3,132	-2,277	-73
625	Otsuka	Abilify Maintena	Aripiprazole	Neurological/Mental Disorders	Yen	Millions	57,000	40,000	513	360	153	43
626	Otsuka	Rexulti	Brexpiprazole	Neurological/Mental Disorders	Yen	Millions	30,000	5,000	270	45	225	500
627	Otsuka	Nuedexta	Dextromethorphan & Quinidine	Respiratory Disorders	Yen	Millions	24,000	19,000	216	171	45	26
628	Otsuka	Pletaal/Pletal	Cilostazol	Cardiovascular Diseases	Yen	Millions	24,000	32,000	216	288	-72	-25
629	Otsuka	Mucosta	Rebamipide	Gastrointestinal Disorders	Yen	Millions	13,000	16,000	117	144	-27	-19
630	Otsuka	TS-1	Tegafur, Gimeracil, Oteracil Potassium	Oncology	Yen	Millions	27,000	29,000	243	261	-18	-7
631	Otsuka	UFT	Tegafur Uracil	Oncology	Yen	Millions	7,000	8,000	63	72	-9	-13
632	Otsuka	Uzel	Calcium Folinate	Oncology	Yen	Millions	10,000	11,000	90	99	-9	-9
633	Otsuka	Lonsurf	Trifluridine And Tipiracil	Oncology	Yen	Millions	30,000	9,000	270	81	189	233
634	Otsuka	Aloxi	Palonosetron	Oncology	Yen	Millions	14,000	13,000	126	117	9	8
635	Otsuka	Abraxane	Paclitaxel Protein-Bound	Oncology	Yen	Millions	21,000	21,000	189	189	0	0
636	Otsuka	E Keppra	Levetiracetam	Neurological/Mental Disorders	Yen	Millions	29,000	23,000	261	207	54	26
637	Otsuka	Samsca/Jinarc	Tolvaptan	Cardiovascular Diseases	Yen	Millions	49,000	42,000	441	378	63	17
638	Otsuka	Mucosta Ophthalmic Suspension	Rebamipide	Ophthalmology	Yen	Millions	5,000	5,000	45	45	0	0
639	Otsuka	Neupro Patch	Rotigotine	Neurological/Mental Disorders	Yen	Millions	11,000	8,000	99	72	27	38
640	Otsuka	Sprycel	Dasatinib	Oncology	Yen	Millions	29,000	31,000	261	279	-18	-6
641	Otsuka	Zosyn/Tazocin	Piperacillin And Tazobactam	Anti-Bacterial	Yen	Millions	9,000	13,000	81	117	-36	-31
642	Otsuka	Diagnostics			Yen	Millions	14,000	12,000	126	108	18	17
643	Otsuka	Parentral Nutrition			Yen	Millions	107,000	106,000	963	954	9	1
644	Otsuka	Pharmaceutical Business Total (Excluding Export)			Yen	Millions	388,000	386,000	3,492	3,474	18	1
645	Otsuka	Total Pharmaceuticals			Yen	Millions	753,000	974,000	6,777	8,766	-1,989	-23
646	Otsuka	Total Nutraceuticals			Yen	Millions	312,000	315,000	2,808	2,835	-27	-1
647	Otsuka	Total Consumer Products			Yen	Millions	35,000	39,000	315	351	-36	-10
648	Otsuka	Others			Yen	Millions	141,000	145,000	1,269	1,305	-36	-3
649	Otsuka	Total			Yen	Millions	1,241,000	1,473,000	11,169	13,257	-2,088	-16
650	Otsuka	Corporate/Eliminations			Yen	Millions	-46,000	-45,000	-414	-405	-9	2
651	Otsuka	Total Consolidated			Yen	Millions	1,196,000	1,427,000	10,764	12,843	-2,079	-16
652	Pfizer	Lyrica Ih	Pregabalin	Neurological/Mental Disorders	USD	Millions	4,165	3,655	4,165	3,655	510	14
653	Pfizer	Viagra Ih	Sildenafil Citrate	Sexual Health	USD	Millions	1,181	1,297	1,181	1,297	-116	-9
654	Pfizer	Chantix/Champix	Varenicline	Neurological/Mental Disorders	USD	Millions	842	671	842	671	171	25
655	Pfizer	Toviaz	Fesoterodine Fumarate	Urology	USD	Millions	258	267	258	267	-9	-3
656	Pfizer	BMP2	Bone Morphogenetic Proteins	Bone Health	USD	Millions	251	232	251	232	19	8
657	Pfizer	Alliance Revenues			USD	Millions	1,588	1,256	1,588	1,256	332	26
658	Pfizer	All Other Internal Medicine			USD	Millions	573	233	573	233	340	146
659	Pfizer	Internal Medicine			USD	Millions	8,859	7,610	8,859	7,610	1,249	16
660	Pfizer	Prevnar/Prevenar 13	Pneumococcal 13-Valent Conjugate	Anti-Bacterial	USD	Millions	5,718	6,246	5,718	6,246	-528	-8
661	Pfizer	Fsme-Immun/Ticovac	Tick-Borne Encephalitis Virus	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	114	104	114	104	10	10
662	Pfizer	All Other Vaccines			USD	Millions	239	104	239	104	135	130
663	Pfizer	Vaccines			USD	Millions	6,071	6,454	6,071	6,454	-383	-6
664	Pfizer	Sutent	Sunitinib Malate	Oncology	USD	Millions	1,095	1,120	1,095	1,120	-25	-2
665	Pfizer	Ibrance	Palbociclib	Oncology	USD	Millions	2,135	723	2,135	723	1,412	195
666	Pfizer	Inlyta	Axitinib	Oncology	USD	Millions	401	430	401	430	-29	-7
667	Pfizer	Xalkori	Crizotinib	Oncology	USD	Millions	561	488	561	488	73	15
668	Pfizer	Xtandi Alliance Revenues			USD	Millions	140	Not Reported	140	Not Reported	140	Not Reported
669	Pfizer	All Other Oncology			USD	Millions	231	194	231	194	37	19
670	Pfizer	Oncology			USD	Millions	4,563	2,955	4,563	2,955	1,608	54
671	Pfizer	Enbrel (Outside The U.S. And Canada)	Etanercept	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	2,910	3,333	2,910	3,333	-423	-13
672	Pfizer	Xeljanz	Tofacitinib Citrate	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	927	524	927	524	403	77
673	Pfizer	All Other I&I			USD	Millions	93	61	93	61	32	52
674	Pfizer	Inflammation & Immunology			USD	Millions	3,928	3,918	3,928	3,918	10	0
675	Pfizer	Benefix	Coagulation Factor Ix	Rare Diseases	USD	Millions	712	752	712	752	-40	-5
676	Pfizer	Genotropin	Somatropin	Rare Diseases	USD	Millions	579	617	579	617	-38	-6
677	Pfizer	Refacto Af/Xyntha	Antihemophilic Factor (Recombinant)	Rare Diseases	USD	Millions	554	533	554	533	21	4
678	Pfizer	Somavert	Pegvisomant	Hormonal Disorders	USD	Millions	232	218	232	218	14	6
679	Pfizer	Rapamune	Sirolimus	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	169	197	169	197	-28	-14
680	Pfizer	All Other Rare Disease			USD	Millions	122	108	122	108	14	13
681	Pfizer	Total Rare Disease			USD	Millions	2,369	2,425	2,369	2,425	-56	-2
682	Pfizer	Consumer Healthcare			USD	Millions	3,407	3,395	3,407	3,395	12	0
683	Pfizer	Pfizer Innovative Health (Ih)			USD	Millions	29,201	26,757	29,201	26,757	2,444	9
684	Pfizer	Lipitor	Atorvastatin Calcium	Cardiovascular Diseases	USD	Millions	1,758	1,860	1,758	1,860	-102	-5
685	Pfizer	Premarin Family	Conjugated Estrogens	Sexual Health	USD	Millions	1,017	1,018	1,017	1,018	-1	0
686	Pfizer	Norvasc	Amlodipine	Cardiovascular Diseases	USD	Millions	962	992	962	992	-30	-3
687	Pfizer	Xalatan/Xalacom	Latanoprost	Ophthalmology	USD	Millions	363	399	363	399	-36	-9
688	Pfizer	Zoloft	Sertraline	Neurological/Mental Disorders	USD	Millions	304	374	304	374	-70	-19
689	Pfizer	Relpax	Eletriptan Hydrobromide	Neurological/Mental Disorders	USD	Millions	323	352	323	352	-29	-8
690	Pfizer	Epipen	Epinephrine	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	386	339	386	339	47	14
691	Pfizer	Effexor	Venlafaxine	Neurological/Mental Disorders	USD	Millions	278	288	278	288	-10	-3
692	Pfizer	Zithromax/Zmax	Azithromycin	Anti-Bacterial	USD	Millions	272	275	272	275	-3	-1
693	Pfizer	Xanax/Xanax Xr	Alprazolam	Neurological/Mental Disorders	USD	Millions	222	224	222	224	-2	-1
694	Pfizer	Cardura	Doxazosin Mesylate	Cardiovascular Diseases	USD	Millions	192	210	192	210	-18	-9
695	Pfizer	Neurontin	Neurontin	Neurological/Mental Disorders	USD	Millions	182	196	182	196	-14	-7
696	Pfizer	Diflucan	Fluconazole	Anti-Fungal	USD	Millions	119	181	119	181	-62	-34
697	Pfizer	Tikosyn	Dofetilide	Cardiovascular Diseases	USD	Millions	153	179	153	179	-26	-15
698	Pfizer	Depo-Provera	Medroxyprogesterone	Sexual Health	USD	Millions	126	170	126	170	-44	-26
699	Pfizer	All Other Legacy Established Products			USD	Millions	4,538	4,689	4,538	4,689	-151	-3
700	Pfizer	Legacy Established Products			USD	Millions	11,194	11,745	11,194	11,745	-551	-5
701	Pfizer	Zyvox	Linezolid	Anti-Bacterial	USD	Millions	421	883	421	883	-462	-52
702	Pfizer	Celebrex	Celecoxib	Bone Health	USD	Millions	733	830	733	830	-97	-12
703	Pfizer	Pristiq	Desvenlafaxine	Neurological/Mental Disorders	USD	Millions	732	715	732	715	17	2
704	Pfizer	Lyrica Eh	Pregabalin	Neurological/Mental Disorders	USD	Millions	801	1,183	801	1,183	-382	-32
705	Pfizer	Vfend	Voriconazole	Anti-Fungal	USD	Millions	590	682	590	682	-92	-13
706	Pfizer	Viagra Eh	Sildenafil Citrate	Sexual Health	USD	Millions	383	411	383	411	-28	-7
707	Pfizer	Revatio	Sildenafil	Cardiovascular Diseases	USD	Millions	285	260	285	260	25	10
708	Pfizer	All Other Peri-Loe Products			USD	Millions	276	362	276	362	-86	-24
709	Pfizer	Peri-Loe Products			USD	Millions	4,220	5,326	4,220	5,326	-1,106	-21
710	Pfizer	Medrol	Methylprednisolone	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	450	402	450	402	48	12
711	Pfizer	Sulperazon	Cefoperazone And Sulbactam	Urology	USD	Millions	396	339	396	339	57	17
712	Pfizer	Fragmin	Dalteparin	Blood Disorders	USD	Millions	318	335	318	335	-17	-5
713	Pfizer	Tygacil	Tigecycline	Anti-Bacterial	USD	Millions	274	304	274	304	-30	-10
714	Pfizer	All Other Sterile Injectable Pharmaceuticals			USD	Millions	4,579	2,563	4,579	2,563	2,016	79
715	Pfizer	Sterile Injectable Pharmaceuticals			USD	Millions	6,018	3,944	6,018	3,944	2,074	53
716	Pfizer	Infusion Systems			USD	Millions	1,158	403	1,158	403	755	187
717	Pfizer	Inflectra/Remsima	Infliximab	Immunology (Organ Transplant, Arthritis etc.)	USD	Millions	192	30	192	30	162	540
718	Pfizer	All Other Biosimilars			USD	Millions	127	33	127	33	94	285
719	Pfizer	Biosimilars			USD	Millions	319	63	319	63	256	406
720	Pfizer	Pfizer Centreone			USD	Millions	718	612	718	612	106	17
721	Pfizer	Total Lyrica	Pregabalin	Neurological/Mental Disorders	USD	Millions	4,966	4,839	4,966	4,839	127	3
722	Pfizer	Total Viagra	Sildenafil Citrate	Sexual Health	USD	Millions	1,564	1,708	1,564	1,708	-144	-8
723	Pfizer	Total Alliance Revenues			USD	Millions	1,746	1,312	1,746	1,312	434	33
724	Pfizer	Pfizer Essential Health (Eh)			USD	Millions	23,627	22,094	23,627	22,094	1,533	7
725	Pfizer	Total Revenues			USD	Millions	52,824	48,851	52,824	48,851	3,973	8
726	Regeneron	Eylea (In United States)	Aflibercept	Ophthalmology	USD	Millions	3,323	2,676	3,323	2,676	647	24
727	Regeneron	Net Product Sales			USD	Millions	3,338	2,689	3,338	2,689	649	24
728	Regeneron	Sanofi Collaboration Revenue			USD	Millions	659	759	659	759	-100	-13
729	Regeneron	Bayer Collaboration Revenue			USD	Millions	744	580	744	580	164	28
730	Regeneron	Other Revenue			USD	Millions	119	75	119	75	44	59
731	Regeneron	Total Revenues			USD	Millions	4,860	4,104	4,860	4,104	756	18
732	Roche	Avastin	Bevacizumab	Oncology	CHF	Millions	6,783	6,684	6,715	6,617	98	1
733	Roche	Herceptin	Trastuzumab	Oncology	CHF	Millions	6,782	6,538	6,714	6,473	242	4
734	Roche	Mabthera/Rituxan	Rituximab	Oncology	CHF	Millions	5,823	5,640	5,765	5,584	181	3
735	Roche	Tarceva	Erlotinib	Oncology	CHF	Millions	1,024	1,181	1,014	1,169	-155	-13
736	Roche	Perjeta	Pertuzumab	Oncology	CHF	Millions	1,846	1,445	1,828	1,431	397	28
737	Roche	Xeloda	Capecitabine	Oncology	CHF	Millions	506	513	501	508	-7	-1
738	Roche	Kadcyla	Trastuzumab Emtansine	Oncology	CHF	Millions	831	769	823	761	61	8
739	Roche	Gazyva/Gazyvaro	Obinutuzumab	Oncology	CHF	Millions	196	128	194	127	67	53
740	Roche	Others			CHF	Millions	1,050	763	1,040	755	284	38
741	Roche	Total Oncology			CHF	Millions	24,841	23,661	24,593	23,424	1,168	5
742	Roche	Mabthera/Rituxan	Rituximab	Oncology	CHF	Millions	1,477	1,405	1,462	1,391	71	5
743	Roche	Actemra/Roactemra	Tocilizumab	Immunology (Organ Transplant, Arthritis etc.)	CHF	Millions	1,697	1,432	1,680	1,418	262	19
744	Roche	Xolair	Omalizumab	Immunology (Organ Transplant, Arthritis etc.)	CHF	Millions	1,498	1,277	1,483	1,264	219	17
745	Roche	Cellcept	Mycophenolate Mofetil	Immunology (Organ Transplant, Arthritis etc.)	CHF	Millions	741	785	734	777	-44	-6
746	Roche	Pulmozyme	Dornase Alfa	Rare Diseases	CHF	Millions	685	652	678	645	33	5
747	Roche	Esbriet	Pirfenidone	Idiopathic Pulmonary Fibrosis	CHF	Millions	768	563	760	557	203	36
748	Roche	Others			CHF	Millions	104	114	103	113	-10	-9
749	Roche	Total Immunology			CHF	Millions	6,970	6,228	6,900	6,166	735	12
750	Roche	Pegasys	Peginterferon Alfa-2A	Infectious Diseases (HIV, Hepatitis etc.)	CHF	Millions	259	538	256	533	-276	-52
751	Roche	Tamiflu	Oseltamivir Phosphate	Infectious Diseases (HIV, Hepatitis etc.)	CHF	Millions	794	705	786	698	88	13
752	Roche	Valcyte/Cymevene	Ganciclovir And Valganciclovir	Immunology (Organ Transplant, Arthritis etc.)	CHF	Millions	306	369	303	365	-62	-17
753	Roche	Rocephin	Ceftriaxone	Neurological/Mental Disorders	CHF	Millions	298	279	295	276	19	7
754	Roche	Others			CHF	Millions	116	160	115	158	-44	-28
755	Roche	Total Infectious Diseases			CHF	Millions	1,773	2,051	1,755	2,030	-275	-14
756	Roche	Lucentis	Ranibizumab	Ophthalmology	CHF	Millions	1,406	1,520	1,392	1,505	-113	-7
757	Roche	Total Opthalmology			CHF	Millions	1,406	1,520	1,392	1,505	-113	-7
758	Roche	Madopar	Levodopa And Benserazide	Neurological/Mental Disorders	CHF	Millions	290	275	287	272	15	5
759	Roche	Others			CHF	Millions	367	373	363	369	-6	-2
760	Roche	Total Neuroscience			CHF	Millions	657	648	650	642	9	1
761	Roche	Activase/Tnkase	Alteplase/Tenecteplase	Cardiovascular Diseases	CHF	Millions	1,108	935	1,097	926	171	19
762	Roche	Neorecormon/Epogin	Epoetin Beta And Epoetin Alfa	Blood Disorders	CHF	Millions	328	366	325	362	-38	-10
763	Roche	Mircera	Methoxy Polyethylene Glycol And Epoetin Beta	Blood Disorders	CHF	Millions	512	475	507	470	37	8
764	Roche	Others			CHF	Millions	1,508	1,447	1,493	1,433	60	4
765	Roche	Total Other Therapeutic Areas			CHF	Millions	3,456	3,223	3,421	3,191	231	7
766	Roche	Total Sales			CHF	Millions	39,103	37,331	38,712	36,958	1,754	5
767	Roche	Royalties And Other Operating Income			CHF	Millions	1,944	2,119	1,925	2,098	-173	-8
768	Roche	Total Pharmaceutical Sales			CHF	Millions	41,047	39,450	40,637	39,056	1,581	4
769	Roche	Diagnostic Division			CHF	Millions	11,473	10,814	11,358	10,706	652	6
770	Roche	Royalties And Other Operating Income			CHF	Millions	116	139	115	138	-23	-17
771	Roche	Total Diagnostic Sales			CHF	Millions	11,589	10,953	11,473	10,843	630	6
772	Roche	Total Group Sales			CHF	Millions	52,636	50,403	52,110	49,899	2,211	4
773	Sanofi	Lantus	Insulin Glargine	Diabetes	Euro	Millions	5,714	6,390	6,057	6,773	-717	-11
774	Sanofi	Apidra	Insulin Glulisine	Diabetes	Euro	Millions	367	376	389	399	-10	-2
775	Sanofi	Amaryl	Glimepiride	Diabetes	Euro	Millions	362	393	384	417	-33	-8
776	Sanofi	Insuman	Insulin	Diabetes	Euro	Millions	129	141	137	149	-13	-9
777	Sanofi	Blood Glucose Meters		Diabetes	Euro	Millions	66	63	70	67	3	5
778	Sanofi	Lyxumia	Lixisenatide	Diabetes	Euro	Millions	33	38	35	40	-5	-13
779	Sanofi	Afrezza	Insulin Human	Diabetes	Euro	Millions	Not Reported	7	Not Reported	7	-7	-100
780	Sanofi	Toujeo	Insulin Glargine	Diabetes	Euro	Millions	649	164	688	174	514	296
781	Sanofi	Other Diabetes			Euro	Millions	Not Reported	8	Not Reported	8	-8	-100
782	Sanofi	Total Diabetes			Euro	Millions	7,341	7,580	7,781	8,035	-253	-3
783	Sanofi	Praluent	Alirocumab	Cardiovascular Diseases	Euro	Millions	105	9	111	10	102	1,067
784	Sanofi	Multaq	Dronedarone	Cardiovascular Diseases	Euro	Millions	353	341	374	361	13	4
785	Sanofi	Total Cardiovascular			Euro	Millions	458	350	485	371	114	31
786	Sanofi	Taxotere	Docetaxel	Oncology	Euro	Millions	179	222	190	235	-46	-19
787	Sanofi	Jevtana	Cabazitaxel	Oncology	Euro	Millions	358	321	379	340	39	12
788	Sanofi	Eloxatine	Oxaliplatin	Oncology	Euro	Millions	170	227	180	241	-60	-25
789	Sanofi	Thymoglobulin	Anti-Thymocyte Globulin	Immunology (Organ Transplant, Arthritis etc.)	Euro	Millions	281	256	298	271	27	10
790	Sanofi	Mozobil	Plerixafor	Oncology	Euro	Millions	152	143	161	152	10	6
791	Sanofi	Zaltrap	Aflibercept	Oncology	Euro	Millions	65	77	69	82	-13	-16
792	Sanofi	Other Oncology			Euro	Millions	Not Reported	258	Not Reported	273	-273	-100
793	Sanofi	Total Oncology			Euro	Millions	1,453	1,504	1,540	1,594	-54	-3
794	Sanofi	Aubagio	Teriflunomide	Neurological/Mental Disorders	Euro	Millions	1,295	871	1,373	923	449	49
795	Sanofi	Lemtrada	Alemtuzumab	Neurological/Mental Disorders	Euro	Millions	425	243	451	258	193	75
796	Sanofi	Total Multiple Sclerosis			Euro	Millions	1,720	1,114	1,823	1,181	642	54
797	Sanofi	Cerezyme	Imiglucerase	Rare Diseases	Euro	Millions	748	757	793	802	-10	-1
798	Sanofi	Cerdelga	Eliglustat	Rare Diseases	Euro	Millions	106	66	112	70	42	61
799	Sanofi	Myozyme	Alglucosidase Alfa	Rare Diseases	Euro	Millions	725	650	769	689	80	12
800	Sanofi	Fabrazyme	Agalsidase Beta	Rare Diseases	Euro	Millions	674	592	714	628	87	14
801	Sanofi	Aldurazyme	Laronidase	Rare Diseases	Euro	Millions	201	195	213	207	6	3
802	Sanofi	Other Rare Diseases Products			Euro	Millions	Not Reported	290	Not Reported	307	-307	-100
803	Sanofi	Total Rare Diseases			Euro	Millions	2,777	3,664	2,944	3,884	-940	-24
804	Sanofi	Sanofi Genzyme (Speciality Care)			Euro	Millions	5,950	6,282	6,307	6,659	-352	-5
805	Sanofi	Plavix	Clopidogrel Bisulfate	Cardiovascular Diseases	Euro	Millions	1,544	1,929	1,637	2,045	-408	-20
806	Sanofi	Lovenox	Enoxaparin Sodium	Blood Disorders	Euro	Millions	1,636	1,719	1,734	1,822	-88	-5
807	Sanofi	Renagel/Renvela	Sevelamer Hydrochloride And Sevelamer Carbonate	Urology	Euro	Millions	922	935	977	991	-14	-1
808	Sanofi	Aprovel	Irbesartan / Irbesartan+Hydrochlorothiazide	Cardiovascular Diseases	Euro	Millions	681	762	722	808	-86	-11
809	Sanofi	Allegra	Fexofenadine Hydrochoride	Respiratory Disorders	Euro	Millions	186	194	197	206	-8	-4
810	Sanofi	Myslee/Ambien/Stilnox	Zolpidem	Sleep Disorders	Euro	Millions	304	306	322	324	-2	-1
811	Sanofi	Synvisc/Synvisc One	Hylan G-F 20	Bone Health	Euro	Millions	408	413	432	438	-5	-1
812	Sanofi	Depakine	Valproate Sodium	Neurological/Mental Disorders	Euro	Millions	416	422	441	447	-6	-1
813	Sanofi	Tritace	Ramipril	Cardiovascular Diseases	Euro	Millions	245	274	260	290	-31	-11
814	Sanofi	Lasix	Furosemide	Cardiovascular Diseases	Euro	Millions	148	162	157	172	-15	-9
815	Sanofi	Targocid	Teicoplanin	Anti-Bacterial	Euro	Millions	149	160	158	170	-12	-7
816	Sanofi	Orudis	Ketoprofen	Bone Health	Euro	Millions	103	156	109	165	-56	-34
817	Sanofi	Cordarone	Amiodarone Hydrochloride	Cardiovascular Diseases	Euro	Millions	122	130	129	138	-8	-6
818	Sanofi	Xatral	Alfuzosin	Urology	Euro	Millions	100	95	106	101	5	5
819	Sanofi	Other Rx Drugs			Euro	Millions	3,347	3,635	3,548	3,853	-305	-8
820	Sanofi	Total Established Rx Products			Euro	Millions	10,311	11,633	10,930	12,331	-1,401	-11
821	Sanofi	Consumer Healthcare			Euro	Millions	3,330	3,492	3,530	3,702	-172	-5
822	Sanofi	General Medicine & Emerging Market			Euro	Millions	14,498	Not Reported	15,368	Not Reported	15,368	Not Reported
823	Sanofi	Generics			Euro	Millions	1,854	1,917	1,965	2,032	-67	-3
824	Sanofi	Total Pharmaceuticals			Euro	Millions	29,244	29,799	30,999	31,587	-588	-2
825	Sanofi	Polio/Pertussis/Hib			Euro	Millions	1,495	1,348	1,585	1,429	156	11
826	Sanofi	Adult Booster Vaccines			Euro	Millions	417	496	442	526	-84	-16
827	Sanofi	Meningitis/Pneumonia			Euro	Millions	633	614	671	651	20	3
828	Sanofi	Influenza Vaccines			Euro	Millions	1,521	1,322	1,612	1,401	211	15
829	Sanofi	Travel And Other Endemics Vaccines			Euro	Millions	368	375	390	398	-7	-2
830	Sanofi	Dengue			Euro	Millions	55	Not Reported	58	Not Reported	58	Not Reported
831	Sanofi	Other Vaccines			Euro	Millions	Not Reported	588	Not Reported	623	-623	-100
832	Sanofi	Vaccines			Euro	Millions	4,577	4,743	4,852	5,028	-176	-3
833	Sanofi	Total Group			Euro	Millions	33,821	34,542	35,850	36,615	-764	-2
834	Sanofi	Companion Animals			Euro	Millions	1,781	1,629	1,888	1,727	161	9
835	Sanofi	Production Animals			Euro	Millions	927	886	983	939	43	5
836	Sanofi	Total Animal Health			Euro	Millions	2,708	2,515	2,870	2,666	205	8
837	Sanofi	Total Aggregate Group Sales			Euro	Millions	36,529	37,057	38,721	39,280	-560	-1
838	Shire	Cinryze	Complement C1 Esterase	Cardiovascular Diseases	USD	Millions	680	618	680	618	62	10
839	Shire	Elaprase	Idursulfase	Genetic Disorders	USD	Millions	589	553	589	553	36	7
840	Shire	Firazyr	Icatibant	Rare Diseases	USD	Millions	579	445	579	445	134	30
841	Shire	Replagal	Agalsidase Alfa	Rare Diseases	USD	Millions	452	441	452	441	11	2
842	Shire	Vpriv	Velaglucerase Alfa	Metabolic Disorders	USD	Millions	346	342	346	342	4	1
843	Shire	Kalbitor	Ecallantide	Dermatology	USD	Millions	52	Not Reported	52	Not Reported	52	Not Reported
844	Shire	Genetic Diseases			USD	Millions	2,698	2,399	2,698	2,399	299	12
845	Shire	Vyvanse	Lisdexamfetamine Dimesylate	Neurological/Mental Disorders	USD	Millions	2,014	1,722	2,014	1,722	292	17
846	Shire	Adderall Xr	Amphetamine, Dextroamphetamine	Neurological/Mental Disorders	USD	Millions	364	363	364	363	1	0
847	Shire	Other Neuroscience			USD	Millions	113	115	113	115	-2	-2
848	Shire	Neuroscience			USD	Millions	2,491	2,200	2,491	2,200	291	13
849	Shire	Hemophilia			USD	Millions	1,789	Not Reported	1,789	Not Reported	1,789	Not Reported
850	Shire	Inhibitor Therapies			USD	Millions	452	Not Reported	452	Not Reported	452	Not Reported
851	Shire	Hematology			USD	Millions	2,241	Not Reported	2,241	Not Reported	2,241	Not Reported
852	Shire	Lialda/Mezavant	Mesalamine	Anti-Inflammatory	USD	Millions	792	684	792	684	108	16
853	Shire	Pentasa	Mesalazine	Gastrointestinal Disorders	USD	Millions	309	306	309	306	3	1
854	Shire	Gattex/Revestive	Teduglutide	Gastrointestinal Disorders	USD	Millions	219	142	219	142	77	54
855	Shire	Natpara	Parathyroid Hormone	Hormonal Disorders	USD	Millions	85	24	85	24	61	254
856	Shire	Other Internal Medicine			USD	Millions	349	344	349	344	5	1
857	Shire	Internal Medicine			USD	Millions	1,756	1,501	1,756	1,501	255	17
858	Shire	Immunoglobulin Therapies			USD	Millions	1,144	Not Reported	1,144	Not Reported	1,144	Not Reported
859	Shire	Bio Therapeutics			USD	Millions	372	Not Reported	372	Not Reported	372	Not Reported
860	Shire	Immunology			USD	Millions	1,516	Not Reported	1,516	Not Reported	1,516	Not Reported
861	Shire	Oncology			USD	Millions	131	Not Reported	131	Not Reported	131	Not Reported
862	Shire	Ophthalmology			USD	Millions	54	Not Reported	54	Not Reported	54	Not Reported
863	Shire	Total Product Sales			USD	Millions	10,886	6,100	10,886	6,100	4,786	78
864	Shire	Total Royalties And Other Revenues			USD	Millions	511	317	511	317	194	61
865	Shire	Total Revenues			USD	Millions	11,397	6,417	11,397	6,417	4,980	78
866	Takeda	Adcetris	Brentuximab Vedotin	Oncology	Yen	Millions	28,100	26,900	253	242	11	4
867	Takeda	Amitiza	Lubiprostone	Gastrointestinal Disorders	Yen	Millions	34,500	38,100	311	343	-32	-9
868	Takeda	Uloric	Febuxostat	Rheumatoid Arthiritis	Yen	Millions	41,900	41,100	377	370	7	2
869	Takeda	Colcrys	Colchicine	Anti-Inflammatory	Yen	Millions	41,800	49,300	376	444	-68	-15
870	Takeda	Nesina	Alogliptin	Diabetes	Yen	Millions	48,700	48,700	438	438	0	0
871	Takeda	Azilva	Azilsartan	Cardiovascular Diseases	Yen	Millions	65,700	57,700	591	519	72	14
872	Takeda	Dexilant	Dexlansoprazole	Gastrointestinal Disorders	Yen	Millions	65,500	73,700	590	663	-74	-11
873	Takeda	Candesartan	Candesartan	Cardiovascular Diseases	Yen	Millions	45,300	91,000	408	819	-411	-50
874	Takeda	Entyvio	Vedolizumab	Anti-Inflammatory	Yen	Millions	129,700	87,100	1,167	784	383	49
875	Takeda	Prevacid/Lansoprazole	Lansoprazole	Gastrointestinal Disorders	Yen	Millions	53,400	95,200	481	857	-376	-44
876	Takeda	Pantoprazole	Pantoprazole	Gastrointestinal Disorders	Yen	Millions	78,800	104,800	709	943	-234	-25
877	Takeda	Leuprorelin	Leuprorelin	Oncology	Yen	Millions	116,700	125,200	1,050	1,127	-77	-7
878	Takeda	Velcade	Bortezomib	Oncology	Yen	Millions	139,100	164,800	1,252	1,483	-231	-16
879	Takeda	Ninlaro	Ixazomib	Oncology	Yen	Millions	20,800	4,000	187	36	151	420
880	Takeda	Takecab	Vonoprazan Fumarate	Gastrointestinal Disorders	Yen	Millions	30,700	5,600	276	50	226	448
881	Takeda	Trintellix/Brintellix	Vortioxetine	Neurological/Mental Disorders	Yen	Millions	29,200	32,400	263	292	-29	-10
882	Takeda	Lotriga	omega-3-acid ethyl esters	Cardiovascular Diseases	Yen	Millions	26,600	21,000	239	189	50	27
883	Takeda	Vectibix	Panitumumab	Oncology	Yen	Millions	18,800	18,400	169	166	4	2
884	Takeda	Reminyl	Galantamine	Neurological/Mental Disorders	Yen	Millions	17,200	15,900	155	143	12	8
885	Takeda	Contrave	Bupropion and Naltrexone	Weight Loss and Obesity	Yen	Millions	4,310	6,940	39	62	-24	-38
886	Takeda	Enbrel	Etanercept	Immunology (Organ Transplant, Arthritis etc.)	Yen	Millions	40,700	41,700	366	375	-9	-2
887	Takeda	Benet	Risedronate Sodium Hydrate	Bone And Joint Diseases	Yen	Millions	8,600	10,100	77	91	-14	-15
888	Takeda	Basen	Voglibose	Diabetes	Yen	Millions	1,700	9,300	15	84	-68	-82
889	Takeda	Actos	Pioglitazone	Diabetes	Yen	Millions	1,600	12,600	14	113	-99	-87
890	Takeda	Rozerem	Ramelteon	Neurological/Mental Disorders	Yen	Millions	7,900	7,300	71	66	5	8
891	Takeda	Alinamin	Fursultiamine	Nutritional Deficiency	Yen	Millions	23,800	24,900	214	224	-10	-4
892	Takeda	Alinamin Health Tonic	Fursultiamine	Nutritional Deficiency	Yen	Millions	15,800	15,000	142	135	7	5
893	Takeda	Biofermin	Bifidobacterium	Gastrointestinal Disorders	Yen	Millions	7,200	10,300	65	93	-28	-30
894	Takeda	Benza	Isopropamide Iodide	Anti-Cholinergic	Yen	Millions	11,700	7,900	105	71	34	48
895	Takeda	Borraginol	Prednisolone Acetate, Lidocaine, Allantoin and Vitamin E	Hemorrhoids	Yen	Millions	4,500	4,400	41	40	1	2
896	Takeda	Calcium	Calcium	Bone And Joint Diseases	Yen	Millions	Not Reported	5,200	Not Reported	47	-47	-100
897	Takeda	Actovegin	Deproteinised Ultrafiltrate of Calf Blood		Yen	Millions	Not Reported	4,200	Not Reported	38	-38	-100
898	Takeda	Tachosil	Human Thrombin/Human Fibrogen		Yen	Millions	Not Reported	4,400	Not Reported	40	-40	-100
899	Takeda	Total Revenues			Yen	Millions	1,851,200	1,835,100	16,661	16,516	145	1
900	Teva	Copaxone	Glatiramer	Neurological/Mental Disorders	USD	Millions	4,223	4,023	4,223	4,023	200	5
901	Teva	Azilect	Rasagiline	Neurological/Mental Disorders	USD	Millions	410	384	410	384	26	7
902	Teva	Nuvigil	Armodafinil	Sleep Disorders	USD	Millions	200	373	200	373	-173	-46
903	Teva	Others			USD	Millions	450	433	450	433	17	4
904	Teva	Total Neuroscience			USD	Millions	5,283	5,213	5,283	5,213	70	1
905	Teva	Treanda And Bendeka	Bendamustine	Oncology	USD	Millions	661	741	661	741	-80	-11
906	Teva	Others			USD	Millions	478	460	478	460	18	4
907	Teva	Total Oncology			USD	Millions	1,139	1,201	1,139	1,201	-62	-5
908	Teva	Proair	Albuterol Sulfate	Respiratory Disorders	USD	Millions	565	549	565	549	16	3
909	Teva	Qvar	Beclomethasone	Respiratory Disorders	USD	Millions	462	392	462	392	70	18
910	Teva	Others			USD	Millions	247	188	247	188	59	31
911	Teva	Total Respiratory			USD	Millions	1,274	1,129	1,274	1,129	145	13
912	Teva	Women'S Health			USD	Millions	458	461	458	461	-3	-1
913	Teva	Other Specialilty Medicines			USD	Millions	520	334	520	334	186	56
914	Teva	Speciality Medicines			USD	Millions	8,674	8,338	8,674	8,338	336	4
915	Teva	All Others			USD	Millions	1,239	774	1,239	774	465	60
916	Teva	Generic Medicines			USD	Millions	11,990	10,540	11,990	10,540	1,450	14
917	Teva	Total Sales			USD	Millions	21,903	19,652	21,903	19,652	2,251	11
918	Valeant	Bausch + Lomb/International			USD	Millions	4,607	4,603	4,607	4,603	4	0
919	Valeant	Branded Rx			USD	Millions	3,148	3,582	3,148	3,582	-434	-12
920	Valeant	Wellbutrin	Bupropion	Neurological/Mental Disorders	USD	Millions	279	306	279	306	-27	-9
921	Valeant	Isuprel	Isoprenaline	Cardiovascular Diseases	USD	Millions	178	224	178	224	-46	-21
922	Valeant	Xenazine	Tetrabenazine	Rare Diseases	USD	Millions	157	223	157	223	-66	-30
923	Valeant	Nitropress	Sodium Nitroprusside	Blood Disorders	USD	Millions	130	219	130	219	-89	-41
924	Valeant	Cuprimine	Penicillamine	Genetic Disorders	USD	Millions	104	70	104	70	34	49
925	Valeant	Zegerid	Omeprazole	Gastrointestinal Disorders	USD	Millions	98	Not Reported	98	Not Reported	98	Not Reported
926	Valeant	Syprine	Trientine Hydrochloride	Genetic Disorders	USD	Millions	88	89	88	89	-1	-1
927	Valeant	Mephyton	Phytonadione	Blood Disorders	USD	Millions	56	58	56	58	-2	-3
928	Valeant	Migranal	Dihydroergotamine Mesylate	Neurological/Mental Disorders	USD	Millions	54	34	54	34	20	59
929	Valeant	Aplenzin	Bupropion Hydrobromide	Neurological/Mental Disorders	USD	Millions	42	40	42	40	2	5
930	Valeant	Other Products			USD	Millions	713	967	713	967	-254	-26
931	Valeant	Other Revenues			USD	Millions	20	32	20	32	-12	-38
932	Valeant	The U.S. Diversified Revenues			USD	Millions	1,919	2,262	1,919	2,262	-343	-15
933	Valeant	Total Revenues			USD	Millions	9,674	10,447	9,674	10,447	-773	-7
934	Vertex	Kalydeco	Ivacaftor	Respiratory Disorders	USD	Millions	703	632	703	632	71	11
935	Vertex	Orkambi	Lumacaftor/ Ivacaftor	Respiratory Disorders	USD	Millions	980	351	980	351	629	179
936	Vertex	Total Product Revenues			USD	Millions	1683	982	1683	982	701	71
937	Vertex	Royalty Revenues			USD	Millions	16.6	24	16.6	24	-7	-31
938	Vertex	Collaborative Revenues			USD	Millions	2	8	2	8	-6	-76
939	Vertex	Total Sales			USD	Millions	1702	1,032	1702	1,032	670	65

Product Sales Data From Annual Reports of Major Pharmaceutical Companies // 2016